PhD student at @Barkailab at the Weizmann Institute of Science
Israel
Joined May 2019
- Tweets20
- Following132
- Followers63
- Likes57
Divya Krishna Kumar retweeted
(1/8) Still wondering how low complexity intrinsically disordered regions (IDRs) guide transcription factors (TFs) to bind in genomes? Previous studies on sequence grammars; our new @MolCell paper takes the next step: de novo design of functional TF IDRs!
cell.com/molecular-cell/full…
Exciting work! @MindelVladimir @SagieBr
(1/13) Exciting findings from our latest study, now published in @NAR_Open as a breakthrough article! academic.oup.com/nar/advance…
Divya Krishna Kumar retweeted
New 📄 by @tamar_jana + @SagieBr
We introduce MPBA, a novel method allowing parallel measurement of TF binding to thousands of designed DNA sequences within cells. We use it to answer a fundamental question - how prevalent is TF binding cooperativity. 1/9 tinyurl.com/2s4bbu65
Divya Krishna Kumar retweeted
I am super excited to share our new paper in @NAR_Open about all the complex ways of how IDRs regulate the binding patterns of Gln3!🥳🎉
Thank you everyone for such an amazing work together, especially @Divya_KKumar @FJonas15 @BarkaiLab
🎉Happy to share our new paper! Intrinsically disordered regions (IDRs) in transcription factors (TFs) encode for complex binding patterns using diverse sequence grammars and interaction types. (1/9)
academic.oup.com/nar/advance…
@bhurieva @Divya_KKumar guided by @FJonas15 @NaamaBarkai
🔥New paper out in @NAR_Open! 🔥
Thrilled to have taken another step towards understanding the role of disordered regions in eukaryotic transcription factor binding specificity
Enjoyed working with the very best @bhurieva @FJonas15 @NaamaBarkai
🎉Happy to share our new paper! Intrinsically disordered regions (IDRs) in transcription factors (TFs) encode for complex binding patterns using diverse sequence grammars and interaction types. (1/9)
academic.oup.com/nar/advance…
@bhurieva @Divya_KKumar guided by @FJonas15 @NaamaBarkai
Divya Krishna Kumar retweeted
Check out our new paper: “Intrinsically disordered regions of the Msn2 transcription factor encode multiple functions using interwoven sequence grammars” published @NAR_Open. The work of @MindelVladimir and @SagieBr. academic.oup.com/nar/advance…
Amazing work by @OffirLupo @BarkaiLab now online in @CellSystemsCP 🔥
🔥Hot from the oven🔥! Our new paper led by @OffirLupo on the role of TF cooperativity in binding specificity is now out in @CellSystemsCP
see🧵below for highlights (1/10)
@WeizmannScience
authors.elsevier.com/c/1hVy6…
Divya Krishna Kumar retweeted
Read the newest chapter of the histone timer⏲️arc in our @NAR_Open paper investigating 🧐 the role of different histone chaperones and remodelers using the . Special thanks to Gilad, it was again great working with you👨🔬 and the other members of the @BarkaiLab👩👧👦. (🧵)
This Post is from an account that no longer exists. Learn more
Divya Krishna Kumar retweeted
New @NAR paper by @FJonas15 & Gilad defining main activities of histone chaperones & chromatin remodelers in nucleosome exchange 🐣
Do they mainly incorporate nucleosomes displaced by transcription? Increase exchange in promoters to enable TF binding?
doi.org/10.1093/nar/gkad615
🤩Our paper is online! We elucidate the role of IDR rich DBD external regions in directing promoter selection. I had great fun, and learned a great deal working with the best team @FJonas15 and @BarkaiNaama
🥳🎉We are delighted to share our new paper that deciphers the complementary strategies by DNA binding domains (DBDs) and IDRs in directing transcription factor (TF) target specificity. 🎉🥳
cell.com/molecular-cell/full…
@Divya_KKumar
@FJonas15
@BarkaiNaama
Divya Krishna Kumar retweeted
🥳🎉We are delighted to share our new paper that deciphers the complementary strategies by DNA binding domains (DBDs) and IDRs in directing transcription factor (TF) target specificity. 🎉🥳
cell.com/molecular-cell/full…
@Divya_KKumar
@FJonas15
@BarkaiNaama
Divya Krishna Kumar retweeted
Online Now: Complementary strategies for directing in vivo transcription factor binding through DNA binding domains and intrinsically disordered regions dlvr.it/Sn9dXZ
🤩Our paper is online! We elucidate the role of IDR rich DBD external regions in directing promoter selection. I had great fun, and learned a great deal working with the best team @FJonas15 and @BarkaiNaama
This quoted post is unavailable.
Divya Krishna Kumar retweeted
Proud to present our 🎉new paper🎉deciphering the IIDR grammar of transcription factor target specificity: doi.org/10.1093/nar/gkad184. Special shout out to my fellow code breakers 🕵️ @BennyKrupkin and MiriCarmi and the rest of the @BarkaiLab - follow 🧵 for highlights
Divya Krishna Kumar retweeted
Excited to share our newest preprint by @TamarGera @FJonas15 & Roye More: Evolution of binding preferences among whole-genome duplicated transcription factors
biorxiv.org/content/10.1101/…
Ever wondered how the transcriptional network evolves? Read more to find out! (1/7)
Divya Krishna Kumar retweeted
Our new paper, led by Gilad Yaakov and @FJonas15 just came out! @NatureBiotech
⏱We used molecular timers to measure histone exchange genome-wide. 1/5
nature.com/articles/s41587-0…
Divya Krishna Kumar retweeted
Thanks to support from @CapgeminiIndia @HFSP we have several positions to work on developing new methods/tests and ask challenging questions in infectious diseases. Please RT ! ! nanobiology.nanobiophotonics…
Divya Krishna Kumar retweeted
We, as citizens of India,
are 'Independent' every day but many of us don't understand it's true meaning.
Unfortunately for many it's 'just' a holiday or a person's birthday to remember once in 365 days. – at Bengaluru, India
Divya Krishna Kumar retweeted
Excited to share my latest work together with @tamar_jana published today @MolecularCell. We focused on how transcription factors that bind similar motifs in-vitro localize to distinct promoter sets in-vivo. @BarkaiLab @WeizmannScience (1/7) cell.com/molecular-cell/full…
