@DimPapad02

Biologist, Postdoc researcher, Assay development for drug discovery projects, in vivo experiments, writing for funding support and patent fillings

 BSRC AL. FLEMING,VARI, GR
Joined February 2020
  • Tweets7
  • Following48
  • Followers48
Dimitra Papadopoulou retweeted
George Kollias@KolliasLab27 Feb 2024
A wonderful collaboration with the medicinal chemistry lab of Alexios Matralis and valued colleagues! First small molecule leads targeting #fibroblast activation driving chronic #inflammatorydisease and #fibrosis.
Angewandte Chemie@angew_chem27 Feb 2024
Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation (George Kollias and co-workers) @KolliasLab onlinelibrary.wiley.com/doi/…

Discovery of the First‐in‐Class Inhibitors of Hypoxia Up‐Regulated Protein 1 (HYOU1) Suppressing...

A multidisciplinary pipeline consisting of medicinal chemistry, molecular phenotyping, chemoproteomics, RNA-sequencing, short hairpin RNAs (shRNAs)-mediated gene silencing and in vivo studies led to...

onlinelibrary.wiley.com
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Dimitra Papadopoulou retweeted
George Kollias@KolliasLab30 Sep 2023
Yes! It's public! Our lab's new work providing the first evidence of spatial spreading of intestinal inflammation via distinct fibroblast subsets. Amazing work .. all because of amazing Lida et al! @BSRC_Fleming @CrohnsColitisFn @ERC_Research biorxiv.org/content/10.1101/…

Cellular complexity and crosstalk in murine TNF-dependent ileitis: Different fibroblast subsets...

Crohn’s disease represents a persistent inflammatory disorder primarily affecting the terminal ileum. Through the application of single-cell RNA sequencing, we unveil the intricate cellular complex...

biorxiv.org
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Dimitra Papadopoulou retweeted
Anastasios Liakos@AnastasiosLiak120 Jul 2023
Proud and extremely happy to see our recent work published  today @NAR_Open! Congratulations to all the (past and present) members of the #MFlab @BSRC_Fleming that contributed! academic.oup.com/nar/advance…

Enhanced frequency of transcription pre-initiation complexes assembly after exposure to UV irradi...

Abstract. In addition to being essential for gene expression, transcription is crucial for the maintenance of genome integrity. Here, we undertook a system

academic.oup.com
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An antipsychotic drug reduces arthritis in a fibroblast dependent model! Take a look on our work from @KolliasLab at @BSRC_Fleming published now in @JCI_insight. Thanks to our collaborators @Biomedcode @JesperOlsenLab
JCI insight
@JCI_insight16 May 2023
Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis: buff.ly/42mYXhy @KolliasLab @BSRC_Fleming #Therapeutics
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Happy that our work at @KolliasLab in @BSRC_Fleming is now available as a preprint! @biorxivpreprint #arthritis #fibroblasts #DrugRepurposing
bioRxiv@biorxivpreprint3 Aug 2022
Repurposing of Amisulpride, a known antipsychotic drug, to target synovial fibroblasts activation in arthritis. biorxiv.org/cgi/content/shor… #bioRxiv
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The @KolliasLab @BSRC_Fleming is seeking motivated #postdocs to join a newly awarded #ERCAdG on “Contextual specification of #fibroblast driven causalities in #IBD and #fibrosis” @ERC_Research Info: bit.ly/3N8KIF3
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Dimitra Papadopoulou retweeted
Nature Immunology@NatImmunol15 Mar 2021
Kollias and colleagues examine FRC development during lymphoid organogenesis in gut PP: two separate mesenchymal cell lineages converge and form mosaic microenvironments that support immune cell activation and maintain intestinal homeostasis rdcu.be/cgNVz
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