Cancer biologist interested in the tumor microenvironment, cell-cell interactions, signal transduction, protein kinases, and kitty cats

Cologne, Germany
Joined April 2012
Beyond excited that the first paper of my PhD journey is out in @NeuroOnc today, reviewing the brain metastatic immune microenvironment. Super grateful for the great collaborative effort, particularly the guidance of @DimHien and @RolandGoldbrunn ! academic.oup.com/neuro-oncol…
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Hien Nguyen retweeted
Excited to share our @lewis_ri_ @HallekMichael perspective on double-refractory (2R) #CLL, now in @BloodJournal. 2R pts are a growing challenge with poor outcomes. We outline the current landscape and explore targets in the tumor microenvironment. #CLL doi.org/10.1182/blood.202302…
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Great pleasure to present our work on the role of RIPK1 in beta cell survival! Congratulations @onayyveli for this amazing piece of work. Thanks a lot to our collabs especially to @CardozoKupper @sfb_1403 @CECAD_ @UniCologne
🔬 Second paper from our lab! RIPK1 is not essential for cell death regulation in pancreatic β-cells. These cells bear a unique mechanism to resist TNF-induced cell death, which might depend on the anti-apoptotic cFLIP. Check out the full study: sciencedirect.com/science/ar…
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As promised, the second issue of our CLL review series is out now at Seminars in Hematology. Check it out if you are interested in CLL biology and mouse models! sciencedirect.com/journal/se…
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JAK inhibition enhances checkpoint blockade immunotherapy in patients with Hodgkin lymphoma | Science science.org/doi/10.1126/scie…
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Hien Nguyen retweeted
For 25 years, the Toll-like Receptor pathway was considered a series of distinct protein complexes that drive inflammation. Today, we report that the entire pathway, from receptor to transcription factor, is executed from within one complex—the myddosome. nature.com/articles/s41586-0…
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Hien Nguyen retweeted
Thrilled to share our characterization of the human tyrosine kinome. Try out the public website: kinase-library.mit.edu/home Wonderful collaboration with @CantleyLab @benturklab @LabYaffe. Many years of work led by Jared Johnson! nature.com/articles/s41586-0…
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📢Open position for Technical Assistant at #IBMG I am looking for the building blocks of my lab at @StuttgartUni. Interested? please apply here 🤩 stellenwerk.de/stuttgart/job… @peltzer_lab @srcsb #IBMG #SRCSB #openposition #Technician
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And a special thanks to @FabrizioMavilia and @vomSteinA #ESHYOUNGREPORTERS, for lively reporting this conference from a scientific perspective! #ESHCLL2024 #ESHCONFERENCES #HAEMATOLOGY #HEMATOLOGY #leusm #CLLsm
#ESHCLL2024: thank you so much Jennifer Brown, Paolo Ghia, @HallekMichael & all faculty for a superb meeting in Vienna & to all participants for engaging so actively with questions & comments! Don't miss upcoming ESH Conferences visit ➡ esh.org #ESHCONFERENCES
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A great way to close the #ESHCLL2024 Day1: a friendly get together, Mentored Poster Walks & informal scientific exchange between colleagues & friends. Thank you to all Poster Presenters & to H. Nguyen @etenhacken @carsten_niemann & A. Rawstron for your mentorship! #ESHCONFERENCES
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Please RT and register: West German Lymphoma Symposium ⁦@HamatologieUk⁩ ⁦⁦@UniklinikEssen ⁦@MedEssen ⁦@unidue⁩ @dgho_eV⁩ #sfb1530 lymphoma-symposium.de/
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Presented now at #ASH23 by @Othman_Al_Sawaf: In a phase 2 trial, anti-PD-1 inibitor tislelizumab + next gen BTK inhibitor zanubrutinib had an overall response rate of 58.3% in patients with Richter's transformation @UniCologne @UKKoeln #leusm #lymsm #CLL doi.org/10.1038/s41591-023-0…
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here is the correct link to apply for a Postdoc position in my lab to investigate cell death and metabolism! jobs-uk-koeln.de/index.php?a…
🔬Postdoc position available in our lab. If you are interested in cell death and metabolism, submit you application or reach out directly to me! Please repost🙏 jobvector.de/stellensuche/?k…öln&distance=50&sort=score&pn=1&jobId=205270
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🔬 Join our lab and explore how age-related epigenetic changes impact cancer development! If you're ready to become a master of iPSCs, apply now for this PhD opportunity. @FOR5504 @sfb1399 @DTG_Cologne @CECAD_ #CMMC jobs-uk-koeln.de/index.php?a…
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🔬Postdoc position available in our lab. If you are interested in cell death and metabolism, submit you application or reach out directly to me! Please repost🙏 jobvector.de/stellensuche/?k…öln&distance=50&sort=score&pn=1&jobId=205270
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Hien Nguyen retweeted
Congratulations Viktoria Kohlhas, opening the #iwCLL2023 YIM by presenting data from @HallekMichael-lab on LYN and CSK in the #CLL-TME. Looking forward to a great weekend with more inspiring CLL research!
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Please RT: We are recruiting a PhD student for a ⁦@dfg_public⁩-funded project in the context of #SFB1530. The focus will be placed on defective T cell function in #CLL ⁦@HamatologieUk⁩ ⁦@UniklinikEssen⁩ ⁦@MedEssen⁩ karriere.ume.de/job-finder/
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Drs. @HallekMichael and Phuong-Hien Nguyen's team at @UniCologne provide mechanistic evidence that LYN regulates the polarization of stromal #fibroblasts to support #leukemic progression. 💡 Learn more in @NatureComms. 👉 go.nature.com/3yMehqM
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