You all. I found a beautiful study to write about @Sensible__Med. A new way to analyze observational studies. Gosh, I am excited. Not only to find this study but also to talk with senior author @DenaZera Post here sensible-med.com/p/the-defin… Podcast tomorrow.

🚨 Excited to share our new paper in @LancetRespirMed 🚨 Our systematic review & network meta-analysis compares preoxygenation strategies for critically ill patients needing intubation. NIPPV tops HFNC & facemask in reducing hypoxaemia. 🔍 Study Highlights • Systematic review & network meta-analysis of 15 RCTs (n=3420) • Compared HFNC, NIPPV, and facemask oxygen for preoxygenation • NIPPV likely best at reducing hypoxaemia during intubation   – vs HFNC: RR 0.73 (moderate certainty)   – vs facemask: RR 0.51 (high certainty) • HFNC better than facemask: RR 0.69 (high certainty) • No strategy improved first-attempt intubation success • NIPPV may reduce serious adverse events vs HFNC/facemask • No clear mortality difference between methods • Data used to inform upcoming international airway guidelines 🧠 Implications: NIPPV may be preferred in high-risk or critically ill patients; findings support evidence-based guideline updates kwnsfk27.r.eu-west-1.awstrac… @UofT_DoM @MacDeptMed @Bram_Rochwerg @DenaZera @HEI_mcmaster