Bright lights, big milestone. β¨
CTx001 is officially headed into the clinic!
@ComplementTx celebrates FDA IND clearance in the heart of Times Square β lighting up the @Nasdaq tower for the second time. π§¬π
π° Media coverage roundup β¬οΈ
#INDClearance #GeneTherapy #BiotechNews
Complement Therapeutics retweeted

BiotechTV@BiotechTV8 Oct 2025
United States
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ππ¨π¦π©ππ§π² πππ°π¬: @ComplementTx received IND clearance from U.S. FDA today to start a trial of its AAV gene therapy for geographic atrophy that delivers a truncated version of Complement Receptor 1 to the eye.
Full video: biotechtv.com/post/complemenβ¦
CTx001 is designed to modulate both classical and alternative complement pathways using a truncated CR1 (mini-CR1), delivered through AAV. A potentially durable, one-time treatment for GA, and this is just the start.
#Biotech #AMD #GeneTherapy #GeographicAtrophy #ClinicalTrial
π Big milestone for @ComplementTx:
Weβve received FDA IND clearance for CTx001, our lead gene therapy for Geographic Atrophy (GA).
Weβre now entering the clinic with Opti-GAIN, a first-in-human Phase I/II trial.
A huge step for the team, and for patients.
#INDClearance #CTx001
We welcome Kate to the team as our Vice President, Regulatory Affairs. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
Complement Therapeutics retweeted
Very pleased to present this online Tutorial around the role of the Complement System in Disease in conjunction with the Stephen J Ryan Initiative for Macular Research (RIMR) and the Doheny Eye Institute
youtu.be/AEkKDDYMcyk?si=FW7k⦠via @YouTube
#complement #Macula @DohenyEye
We welcome Jen to the team as our Vice President, Clinical Operations. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
Complement Therapeutics retweeted
Great to see @ComplementTx gaining recognition for its work on the Complement Precision Medicine (CPM) platform. Patient stratification should be a major focus for clinical success. @RDUnwin #complementbiology #complementsystem #immunology
ukt.news/is-biotechs-future-β¦
Please join us in extending a warm welcome to our Chief Technology Officer, Dr. Matthias Hebben! π
Read more about Matthias and our continued growth in the full release here: bit.ly/3TbgxDr
#biotech #ophthalmology #genetherapy #complement #chieftechnologyofficer #CTO
π’The first patient enrolled in our i-GAIN Natural History Study!
We will be recruiting 250 patients with geographic atrophy (#GA) secondary to age-related macular degeneration (#AMD) across the UK and US over the next 12 months.
Find out more here:Β bit.ly/465S2KW
We welcome Sofiya to the team as our Scientist, Pharmacology. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
We welcome Thanos to the team as our Director, Pharmacology. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
Complement Therapeutics retweeted
A comprehensive review by @ProfClark M. Ueffing et al discusses the role of #complementbiology in #ocular disease, provides overview of #therapeutics & raises awareness on #time of intervention, proper #delivery routes & #patient selection
Worth reading!
sciencedirect.com/science/arβ¦
We welcome Rachel to the team as our Director, Biomarker/Bioanalytical. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
We welcome Rachel to the team as our Senior Vice President, Development Operations. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
We welcome Nakul to the team as our Scientist, Analytical Development. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
We welcome Suhnrita to the team as our Senior Scientist, Pharmacology. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
Please join us in extending a warm welcome to our Chief Medical Officer, Dr. Parisa Zamiri, MD! π
Read more about Parisa and our continued growth in the full release here: bit.ly/44Vp9kS
#biotech #ophthalmology #genetherapy #complementbiology #chiefmedicalofficer #CMO
We welcome Patience to the team as our Business Administration Manager. π
#WelcomeAboard #GeneTherapy #ophthalmology #ComplementBiology #team #JobOpening #JoinUs
Complement Therapeutics retweeted
We've been recognised by @Labiotech_eu as one of six biotech spinouts around the world to keep an eye on! π
Read more here: bit.ly/44xM6Km
#biotechnews #innovation #genetherapy #research #AMD
















