Collateral Medical

People with persistent irreversible brain disorders come to us as a last resort. And we re-diagnose them. We turn their original diagnosis upside down and treat them. The brain disorder reverses. Patients get their lives back. New episode #MustWatch youtu.be/NJWos8prZhI?si=XDCj…

I just f**king love how the @BBCOne destroyed the "social drinking is pretty much ok" myth with this fantastic narrative which is only a bit over 60 seconds. We need more of this. Much more. Featuring marvellous Hepatologists from across the UK including Prof. @DebbieShawcros1 Remember. A woman can get severe liver disease with lower limits of alcohol use than men. It's not the liver disease I'm worried about, it's the terrifying breast cancer. And 20 other types of cancers including the most hellish of them all, pancreatic cancer (the pain cannot be described). Alcohol is not beneficial in any dose, or form. Prof. Debbie Shawcross mentioned liver failure in 20 year olds due to alcohol use. My youngest patient that fell victim to alcohol was only 19. He vomited nearly half his total blood volume...collapsed at home...hit his head on the floor...bled into his brain...went into a coma...died on the ventilator, all in 2 days time. Just 19 years old. Read more on this here: #mustread ‘I had no idea being a social drinker would damage my liver by 31’ by @hazelreporting for @BBCPanorama bbc.com/news/articles/c30pre…

Tips for liver health in six minutes Full video link: The Liver Doc x BeerBiceps on The Ranveer Show: Episode 1 youtu.be/Rg5lbQj62Og?feature…

Hey do you want to hear something really cool about the liver? You know that we have a 'body clock,' right? This internal biological clock is responsible for the 'circadian rythmn' that drives various body processes in a 24 hour period. Circadian rhythms are physical, mental, and behavioral changes that follow a 24-hour cycle. One of the most important and well-known circadian rhythms is the sleep-wake cycle. Circadian rhythms are influenced by light and dark, as well as other factors. But what controls these biological clocks? A master clock - which resides in the brain. In humans, the master clock is a group of about 20,000 nerve cells (neurons) that form a structure called the suprachiasmatic nucleus, or SCN. The SCN is in a part of the brain called the hypothalamus and receives direct input from the eyes. But a group of researchers from the University of Queensland has found that it was not just the brain, but also the liver - that functions as the master clock! To figure this out, they turned to our best lab buddies - mice. Mice are nocturnal animals...meaning, they are very active at night and mostly finish off their napping sessions (a mouse sleeps for 12h a day) during the day and late evenings. But these researchers did something strangely cool. They transplanted human liver cells into mice, to replace their mousy-liver cells. And the mice started behaving weird. They ate and slept at different times compared to mice without transplanted human cells. The mice started to eat and be active before night-time began, which was very unusual for a nocturnal animal. Basically, their biological clock became more "human." What does this mean? The liver is a master organ. It has more secrets in it, than we can ever imagine, but will unlock in due time. And any disease affecting the liver, can disrupt your circadian rythmn/ biological clock... ...which is why in patients with cirrhosis - their sleep-wake cycle is disrupted - they tend to sleep more during day, and are more active at night (like an actual mouse) - a condition called minimal (covert) hepatic encephalopathy. This is also the reason why patients with diabetes, when they have fatty livers, they have disrupted sleep - many people with type 2 diabetes experience poor sleep quality or insomnia. If the liver is healthy, your normal functioning, especially sleep-wake cycles, become better. So remember, keep yourselves healthy so that your liver, the master clock remains healthy. Here are fews tips on keeping a healthy liver in case you missed it before. Here xitter.cf/theliverdr/statu… and here xitter.cf/theliverdr/statu… Source: Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior science.org/doi/10.1126/scia…

HERE ARE NINE SIMPLE LIFE HACKS that you can include in your daily living and activities that improve liver-health as well as overall health and longevity. Please share widely so that everyone can benefit. And it does not feature any podcaster promoted supplements or crazy routines like cold showers or injecting blood of your children to look younger. DAILY WALKING Walking 8000 to 10,000 steps a day in young and 6000 to 8000 steps a day in elderly increases longevity and well-being and reduces death from all-causes including cancers. Walk for a minimum of 30 minutes to one hour and not lesser. The more steps, the better the results. pubmed.ncbi.nlm.nih.gov/3524… BRISK WALKING Walking 100 steps in a minute (brisk walking) reduces liver fat without even weight loss. Brisk walking for at least 150 minutes per week ensures this positive outcome. pubmed.ncbi.nlm.nih.gov/3670… RUNNING Running even once a week was associated with increased well-being, longevity and reduced risk of dying from lifestyle diseases including various cancers. Just once a week! The more you do it, the better it is for you. pubmed.ncbi.nlm.nih.gov/3168… ACTIVE VIDEO GAMING In elderly persons or those who cannot perform outdoor or trained physical activity, playing “Active-Video-Games,” i.e., gaming which requires active participation without being sedentary, improves balance, posture, gait speed and mobility. Such improvements can later be used to tolerate conventional physical activity. pubmed.ncbi.nlm.nih.gov/3493… CONVENTIONAL VIDEO GAMING Conventional and five days a week video gaming after work improves mindfulness, reduces post work fatigue and stress, and increases productivity. mental.jmir.org/2019/7/e1285… SLEEP Sleep at least 7 hours a night. Do not nap for more than one hour in the daytime (or try to completely avoid it) and try to catch up lost sleep hours (of weekdays) during the weekend. This reduces chances of getting fatty liver, improves fatty liver disease and reduces risk of developing progression of fatty liver. pubmed.ncbi.nlm.nih.gov/3591… pubmed.ncbi.nlm.nih.gov/3519… ncbi.nlm.nih.gov/pmc/article… COFFEE & TEA Three cups of black coffee without milk or sugar (may use zero calorie sweeteners as desired, but would advise avoiding that too) in a day reduces risk of fatty liver, reverses liver fibrosis, reduces risk of progression of fatty liver disease to cirrhosis and lowers liver fat especially in those with diabetes. ncbi.nlm.nih.gov/pmc/article… pubmed.ncbi.nlm.nih.gov/3661…. Unfortunately, the same cannot be said for tea because the quality of evidence is weak (ncbi.nlm.nih.gov/pmc/article…) ALCOHOL Complete abstinence from alcohol increases longevity, well-being, productivity and absolutely reduces the chances of getting almost 30 types of cancers and several other metabolic diseases. Which means, you get to spend more quality time with family on this earth. thelancet.com/article/S0140-… jamanetwork.com/journals/jam… NIGHT TIME EATING/SNACKING Night time eating or late-night snacking was associated with increased risk of metabolic disease, obesity, poor quality of sleep and longer but more inefficient duration of sleep. Avoid eating food at least within three hours before bedtime (weak evidence). ncbi.nlm.nih.gov/pmc/article… ncbi.nlm.nih.gov/pmc/article… pubmed.ncbi.nlm.nih.gov/3451… To summarize, walk at least 8000 steps a day, run at least once a week, try to brisk walk 150 minutes a week, sleep for minimum 7 hours a day, but not more than 9 hours, play active video games every day, play conventional video games five days a week to reduce work fatigue, avoid alcohol and drink 3 cups of unsweetened black coffee. See, none of these feature “actual medicines.”