@ChingHoChang
Joined September 2014
  • Tweets126
  • Following165
  • Followers229
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I’m thrilled to announce the launch of the Evolution of Chromosomes and Genomes (ECG) Lab at the Institute of Molecular Biology, Academia Sinica, Taiwan.Our lab website is now live—come check it out! sites.google.com/view/ecg-la…

ECG LAB

"The only constant in life is change." — Heraclitus Genetic conflicts — the good, the bad, and the ugly — shape our lives over time We aim to understand why even the most essential genes and chromo...

sites.google.com
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We’re actively recruiting at all levels: RAs, MS students, PhD students, and postdocs. If you’re passionate about evolutionary biology and excited to explore how lives are shaped by genetic conflicts, we’d love to hear from you! sites.google.com/view/ecg-la…

ECG LAB - JOIN US

We are always excited to welcome motivated and curious people to join us! Please check our VALUES first!

sites.google.com
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Finally, a huge thank you to my mentors Chau-Ti Ting, @AmLarracuente and @HarmitMalik, collaborators, and friends for their support. Special credit to Harmit for the lab name and logo inspiration.
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Ching-Ho Chang retweeted
PLOS Biology@PLOSBiology22 Nov 2024
Rapid centromere evolution: @CecileCourret @AmLarracuente &co's study of #centromere #evolution over short timescales in #Drosophila reveals dramatic #centromere reorganization involving recurrent shifts between retroelements & satellites #PLOSBiology plos.io/3CBwHQe
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Exciting news, fellow #Drosophila researchers! Ever wondered about the genome sequence of your lab strain or the balancers? Check out our Drosophila Laboratory Pangenome Database, featuring a growing collection of reference genome assemblies for popular D. melanogaster strains!
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Curious how diet may influence the regulation of transposable elements? Join us! We have an NIH-funded technician position available immediately. Especially ideal for post-bac wanting more research experience before grad school. Please help spread the word. Thank you!
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Ching-Ho Chang retweeted
Tera Levin@tera_levin3 Sep 2024
Hello folks! With exciting new grants and new projects in our lab, ✨we are hiring!✨ Please share with prospective Ph.D. students and/or postdocs interested in evolution, genetics, and microbes!
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Ching-Ho Chang retweeted
Mahul Chakraborty@mahulchak3 Sep 2024
We're recruiting a postdoc. Lab works on diverse topics related to genetic variation. More here: chakrabortylab.org/research/ Competitive salary & strong support for trainee’s career growth!Informal inquiries are welcome. chakrabortylab.org/join-us/ #Genetics #Postdoc #ResearchOpportunity
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Ching-Ho Chang retweeted
Gavin Rice@gavinrrice6 Mar 2024
Posting for @mobilepurin The Lee lab @mobilepurin is excited to be at #TAGC24!! We have multiple presentations about how transposons shape genome evolution through epigenetic mechanisms! Would love to chat science!! We are also recruiting!
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Gavin Rice@gavinrrice6 Mar 2024
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Paul Talbert@PaulTalbert1015 Nov 2023
Human satellite centromere expansions and contractions can be measured in ~20 cell generations and depend on RAD52 and PIF1, suggesting break-induced replication biorxiv.org/content/10.1101/…

Expansion of human centromeric arrays in cells undergoing break-induced replication

Human centromeres are located within α-satellite arrays and evolve rapidly, which can lead to individual variation in array lengths. Proposed mechanisms for such alterations in lengths are unequal...

biorxiv.org
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Thrilled to be part of this exciting project, learning a lot from the brilliant minds of Dr. Dubruille and Dr. Loppin. The experimental designs are as elegant as art, unveiling unexpected, fundamental discoveries. science.org/doi/10.1126/scie…

Histone removal in sperm protects paternal chromosomes from premature division at fertilization

Histone retention in Drosophila sperm chromatin jeopardizes paternal chromosome integrity during female meiosis.

science.org
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Excited to share our latest study on fungal-bacterial competition! What drives their competition and how does it impact microbial evolution? We found Mg2+ is the key. Grateful for my mentors’ support! (1/11) @HarmitMalik @ajai_dandekar @thehoganlab biorxiv.org/cgi/content/shor…
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Widespread fungal-bacterial competition for magnesium enhances antibiotic resistance biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Ching-Ho Chang retweeted
bioRxiv@biorxivpreprint24 Oct 2023
Germline novelty through recurrent copy-number, protein, and regulatory evolution of the synaptonemal complex biorxiv.org/cgi/content/shor… #bioRxiv
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Check out the full story on bioRxiv! biorxiv.org/content/10.1101/…

The diverse evolutionary histories of domesticated metaviral capsid genes in mammals

Selfish genetic elements and their remnants comprise at least half of the human genome. Active transposons duplicate by inserting copies at new sites in a host genome. Following insertion, transpos...

biorxiv.org
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Ching-Ho Chang retweeted
Harmit S. Malik@HarmitMalik4 May 2023
We have 2 res. tech. openings in our lab starting soon. Please RT & bring this to the attention of students interested in getting hands-on experience in the lab before heading to grad/ med school. We value curiosity, mentorship, & diversity. 1st position: jobrxiv.org/job/research-tec…

Research Technician I- Malik Lab

Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

jobrxiv.org
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Happy coincidence! Lab renovation and website are done on the same day! Check out our lab website. chakrabortylab.org/ We're recruiting postdocs (formal ad coming soon). If you're into any of these: CRISPR, genomes, SVs, complex traits, experimental evolution, write to us.
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Struggle between sex chromosomes underlies evolutionary paradox. ⁦@HutchBasicSci⁩ Work by ⁦@ChingHoChang⁩ and ⁦@isamess10⁩ now out in ⁦@eLife⁩; check out the nice writeup by Sabrina Richards ⁦@fredhutch⁩ fredhutch.org/en/news/center…

Struggle between sex chromosomes underlies evolutionary paradox

Fred Hutchinson Cancer Center scientists have discovered that an arms race between sex chromosomes, each jockeying to pass itself to the next generation, lies behind the unexpectedly fast evolution...

fredhutch.org
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