@CadwellLab

We investigate the interface between the immune system and diverse infectious agents ranging from friendly gut microbes and viruses to disease-causing parasites

 Philadelphia, PA
med.upenn.edu/cadwell-lab
Joined September 2019
  • Tweets412
  • Following319
  • Followers1.8K
57Media
Cadwell Lab retweeted
Cadwell Lab@CadwellLab8 Mar 2025
Congratulations @YingHanChen7121 and Kim Zaldana for showing how B cells are altered when lab mice are released outdoors! science.org/doi/10.1126/scia… 1/n

Rewilding catalyzes maturation of the humoral immune system

Releasing laboratory mice into the natural environment enhanced maturation and activation of the humoral immune system.

science.org
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Donald Trump and @elonmusk are trying to rob us blind. This is the biggest scam in history and half the country thinks this is all a great idea. They are stealing your (our) money! Wake up! He set Social Security up for a huge dismantling last night. Just watch...
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Cadwell Lab retweeted
Penn Microbiology@PennMicro24 Sep 2024
The time has come for the annual PennCHOP Microbiome symposium! Registration is now open and we are accepting abstract submissions. The dates for the symposium are Thursday, December 5th and Friday December 6th 2024. To register: eventbrite.com/e/2024-pennch…
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Cadwell Lab retweeted
Penn IGG@IGGPenn10 Oct 2024
Oh hello! IGG is hosting our annual Virtual Admissions Open House on Nov 4 & 6 (7pm both nights). Register with the qr code or here: forms.gle/cG4DFAHkERac6PQn6 Attend both nights and you're eligible for feedback on your application from current students. Hope to see you there!!!
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Allison Cohen just won first prize for her talk & poster on Cryptosporidium invasion at today’s NIH Center for Molecular Studies in Digestive and Liver Diseases Symposium. Congrats - great job on research & presentation.
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New research out in @ScienceMagazine describes the development of a multivalent mRNA-LNP vaccine for Clostridioides difficile (#cdiff) infection ft. @MgAlameh, @_alexafluor, @joeyzacks (@PennPathLabMed/ @CHOP_Research) & @WeissmanLab (@PennMedicine) tinyurl.com/ykmfsa5u
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We are searching for an Asst Professor in Immunology and Molecular Medicine @berkeleyMCB @UCBerkeley. Any area of immunology, broadly defined. Deadline is Nov 1. Please help us spread the word and RT! Go Bears! aprecruit.berkeley.edu/JPF04…
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Cadwell Lab retweeted
Abt Lab@abt_lab3 Oct 2024
Check out this fantastic new article by the Zackular lab. Great work! @joeyzacks , @MgAlameh and team. A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection | Science science.org/doi/10.1126/scie…

A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection

Clostridioides difficile infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)–lipid nanoparticle (LNP) vaccine...

science.org
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My doctoral work is now published in @eLife! elifesciences.org/reviewed-p… We found that a protective microbiome and a female hormone enhanced Th17/neutrophil response confer resistance against gut colonization by the pathogen S. aureus
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The work is now out in @elife: Sex-dependent gastrointestinal colonization resistance to MRSA is microbiome and Th17 dependent doi.org/10.7554/eLife.101606… Great job by PhD studnet @AlannahLejeune! Awesome collaboration with @CadwellLab and Bo Shopsin (@nyugrossman).
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We are all living in a bubble that deprives us of experiences needed to understand the true magnitude of the threat posed by the rise of multi-drug resistant infections. It would be wise to allocate resources that match the severity of the threat. science.org/doi/10.1126/scie…
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Cadwell Lab retweeted
Alec Downie@ae_downie12 Sep 2024
We have a new paper out (actually for a little bit now) in @discovimmunol! In this one, we (@Grahammunology et al.) tackle the question of how to infer immune phenotypes in wild settings when you have limited techniques at your disposal. academic.oup.com/discovimmun…

Assessing immune phenotypes using simple proxy measures: promise and limitations

Abstract. The study of immune phenotypes in wild animals is beset by numerous methodological challenges, with assessment of detailed aspects of phenotype d

academic.oup.com
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We are hiring an Assistant Professor in Cancer Pathobiology at CHOP/Penn. This is a great opportunity to join the fantastic Penn community. Please apply & share. apply.interfolio.com/152601
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Fantastic @PennMicro seminar by Jon Kagan @jkagan1 on the beautiful recent study by his postdoc @DanielHFisch on the cell biology of TLR and Myddosome signaling! Thanks so much Jon for sharing your research and spending the day with us! 🙏
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Hear from a talented lineup of immunologists next Wednesday, Sept 18 featuring @zurisullivan, @alexwellsies, @DjenetBousbaine, @ValeriaMReyes, @CicaCanesso, @ScientistBecs, @Liwen_Deng811, & @NZanluqui. Register: bit.ly/ScrippsLeaders
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Join us at CHOP! Work alongside Drs @joeyzacks , @pauljplanet and myself. Be at the forefront of innovation with our newly launched Center of Emphasis—the Center for Microbial Medicine. careers.chop.edu/xxWP6tN
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Meet the Early-Career Scientists Selected for the 2024 IAI New Voices in Microbiology Collection. journals.asm.org/topic/sss-t…
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Cadwell Lab retweeted
Harry Sokol@h_sokol30 Jul 2024
Mucosal Single-Cell Profiling of Crohn's-Like Disease of the Pouch Reveals Unique Pathogenesis and Therapeutic Targets ⁦@AGA_Gastro⁩ sciencedirect.com/science/ar…
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1/9 Check out our new paper on "SARS-CoV-2 infection predisposes patients to coinfection with Staphylococcus aureus" in @mbiojournal journals.asm.org/doi/full/10…

SARS-CoV-2 infection predisposes patients to coinfection with Staphylococcus aureus | mBio

The COVID-19 pandemic has had an enormous impact on healthcare across the globe. Patients who were severely infected with SARS-CoV-2, the virus causing COVID-19, sometimes became infected with other...

journals.asm.org
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1/7 Happy to share a new publication from the team spearheaded by @Keenan__Lacey published today in @ScienceAdvances. This project was started at @nyugrossman and was completed @StJudeResearch by @APickrum and A. Castellaw. science.org/doi/10.1126/scia…

Dietary and water restriction leads to increased susceptibility to antimicrobial resistant pathogens

Dietary and water restriction increases susceptibility to antimicrobial resistant pathogens by disrupting macrophage function.

science.org
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