Würzburg + Berlin University & CERU. Passionate about Critical Care Medicine, Cardiac Surgery, Nutrition and perioperative Care - Time to Improve!
Aachen, Deutschland
Joined April 2018
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🧠 Most burn treatments still rely on very low-level evidence, that must change…
jamanetwork.com/journals/jam…
#VICTORYtrial #JAMA #BurnCare #CriticalCare #ICU #EvidenceMatters
🔥💉 High-dose IV vitamin C for severe burns?
Our large intern. RCT says:
❌ no survival benefit
❌ no shorter hospital stay
❌ no less organ failure
📉 Another null result. Physiology ≠ clinical benefit.
🧵 Read the thread & trial 👇
ja.ma/49RpUzX
#CCR26 #VitaminC
Christian Stoppe retweeted
🚨 The 3rd trial for CCR Frankfurt is SWEET-WATER
5% Glucose or 0.9% saline for ICU drug dilution?
📅 22–23 February 2027
📍 Goethe University Frankfurt
Registration opens shortly
criticalcarereviews.com/meet…
Excellent summary!!!
Day1 at #CCR26
#LOGICALtrial: conservative O₂ after cardiac arrest
#MARCHtrial: carbocisteine +/or HTS for airway secretions
#VICTORYtrial: high-dose IV vitaminC in burns
None improved outcomes; MARCH and VICTORY➡️possible harm!
✅#TeleRehabTrial: in AHRF pts, ⬆️QoL+⬇️mortality
Christian Stoppe retweeted
➡️ Severe burns trigger profound inflammation, capillary leak & organ dysfunction
➡️ Could high-dose vitamin C modify this?
➡️ Join us at #CCR26 for the VICTORY trial results, presented by @CStoppe
Full, free livestream — but it’s better in person
criticalcarereviews.com/meet…
ALT Flyer for the VICTORY trial at CCR26
🕒 48h is the sweet spot.
…- More isn't better!
👉🏽 another reminder in critical care: knowing when to stop is as important as knowing when to start!
#AKi #health #protein
Timing matters. 🕒
IV amino acids for kidney protection in cardiac surgery:
✅ ≤48h → benefit
⚠️ >48h → possible harm (↑urea, ↑ICU mortality?)
❤️ A 48h window may be the sweet spot
#AKI #CardiacSurgery #TimingMatters ping @giovannilandoni @CStoppe bjanaesthesia.org/article/S0…
👉 Nutrition in the ICU is not a checkbox — it is a dynamic, physiology-driven intervent. that requires contin. reassessment. Further key messages @ISICEM :
🔹 Micronutrients: more ≠ better
🔹 Protein: we underdeliver, but pls. stay <1.3g!
🔹 Timing matters
🔹 Calories = a drug
Day -1 of #ISICEM2026 is off to a great start with the pre-courses! Deep dives into measuring metabolic tolerance & GI function to better guide enteral & parenteral feeding. Great discussions on optimizing icu nutrition 🏥💉📊 #ICU #CriticalCare #Nutrition
How should we really feed the injured brain? ⚡️🧠
💡Key takeaway: Start low, go slow. Early low-dose enteral nutrition is preferred—early full feeding may cause harm.
#NeuroCriticalCare #ICU #Nutrition #BrainInjury #health
👉🏽 link.springer.com/article/10…
Is nutrition just "supportive care" for the injured brain? 🧠 We argue it's a modifiable therapy that can influence recovery.
🥄 Why early low-dose EN is preferred
⚡ The role of ketogenic diets & lactate
📊 Urgent need for trials rdcu.be/e7NLv
#NeuroICU #MedTwitter
Christian Stoppe retweeted
Peri-operative fasting in adults: an international, multidisciplinary consensus statement
#anaesthesia #MedTwitter
doi.org/10.1111/anae.70130
👉How do you feed ECMO patients? New 2025 ELSO consensus statement fills a major guideline gap with 16 practical recommendations for nutrition therapy in adult ECMO patients.
#ECMO #ICU #CriticalCare #MedTwitter2025 ovid.com/jnls/asaiojournal/f…
Christian Stoppe retweeted
As 2025 comes to a close, the ERAS Cardiac Society thanks the global community advancing enhanced recovery after cardiac surgery.
Grounded in evidence and collaboration, we remain focused on improving patient recovery and expanding education and implementation in 2026.
Christian Stoppe retweeted
On the 8th day of Christmas, my true love gave to me…
🎄 8 ventilators humming
🎅 7 nurses charting
🫁 6 lungs oxygenating
💉 5 infusions avoided
📊 4 outcomes hierarchised
📞 3-month follow-up
🌬️ 2 sedation strategies
🐦 And a partridge asleep in a pear tree
#CCR26
Looking ahead to what promises to be an excellent and unique meeting in June 2026 in Belfast !#ClinicalTrials #FutureResearch #icu #trials
🎄 On the sixth day of Christmas my true love gave to me
🍊 five juicy oranges
🍏 four green apples
🐦 three burnt partridges
🏆 And finally a vitamin C trial ending in VICTORY....
#CCR26
criticalcarereviews.com/meet…
Christian Stoppe retweeted
For critically ill patients who had both severe metabolic acidemia and moderate to severe acute kidney injury, sodium bicarbonate therapy did not significantly decrease day 90 all-cause mortality.
ja.ma/48uJPnZ
Christian Stoppe retweeted
Original Article: A Pragmatic Trial of Glucocorticoids for Community-Acquired Pneumonia (SONIA trial) nej.md/47glh02
Editorial: Glucocorticoids for Pneumonia in Africa — Old Therapy, New Context nej.md/4qgjdxH
#Pulmonology #CriticalCare
ALT A graph of the cumulative risk of death from any cause.
Christian Stoppe retweeted
Presented at CCR Down Under 2025:
In a randomized trial involving critically ill patients undergoing intubation in EDs or ICUs, the use of ketamine for the induction of anesthesia did not lead to significantly lower in-hospital mortality than etomidate. Full trial results: nej.md/44EOlxB
@CritCareReviews
ALT CCR Down Under 2025 Original Article | Dec. 9, 2025 | NEJM.org Ketamine or Etomidate for Tracheal Intubation of Critically Ill Adults Figure 1. In-Hospital Death, According to Trial Group. The NEJM identity sits at the bottom.
Christian Stoppe retweeted
Co-Chief Investigators Jonathan Casey and Matthew Semler share their insights from the #RSI trial after presenting at #CCRdownunder
Livestream -> criticalcarereviews.com
@jama_current
A stepwise, phase-adapted strategy for #ICU nutrition seems the 💡.
1. Acute catabolic → Start low
2. Stabilization → Advance cautiously
3. Recovery → Increase for rehab
🔑 Start low, advance judiciously, individualize 🙋🏼♂️
journals.lww.com/co-clinical…
Christian Stoppe retweeted
Today's Paper of the Day is:
Pulmonary artery catheterisation
criticalcarereviews.com/late…
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
