@BronstrupLab

Chemical Biology | Antinfectives Screen | Targeted Drug Conjugates | Metabolomics | Mode-of-Action Studies @Helmholtz_HZI @LeibnizUni @DZIF

 HZI Braunschweig
Joined November 2020
  • Tweets49
  • Following113
  • Followers294
4Media
Brönstrup Lab retweeted
DZIF (inaktiv)@DZIF_5 Nov 2024
🚀 Gemeinsamer Erfolg in der KI-Forschung! 🇩🇪🇫🇷 Ein deutsch-französisches Team, darunter DZIF-Wissenschaftler, erhält einen ERC Synergy Grant über 11 Mio. Euro. Ziel: Entwicklung eines KI-gestützten Ansatzes für die Suche nach neuen Antibiotika: dzif.de/de/erc-synergy-grant… #ERCSyG
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The HZI is looking for game changers in infection research and hiring Junior Research / Technology / Clinician-Scientist Group Leaders (with W1-professorship & tenure options). Join our program #HUMAN and study the complex interplay of humans & microbes! helmholtz-hzi.de/en/career/j…
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Our study on the last resort antibiotic colistin was just accepted by Angew Chem. (bit.ly/4dF8q9n). We reduce its renal cell toxicity by a two-component strategy and bioorthogonal chemistry. #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover
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Brönstrup Lab retweeted
SchulzLab@LabSchulz4 Mar 2024
Volatile salinilactones, produced by the bacterium Salinispora, target disulfide-isomerases. See doi.org/10.1002/advs.2023095… in Advanced Science, by K. Jerye et al. of the @BronstrupLab. This is one of the first studies describing how bacterial volatiles act.
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Full program available, few days and <40 seats left for registration: 3rd Helmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. helmholtz-hzi.de/de/hddc2023 (1)
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(2) Major topics (novel antiinfectives, computational methods, new concepts, two free-of-charge workshops) introduced by international speaker panel. @UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @UniHannover @tuBraunschweig @EuroMedChem
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Brönstrup Lab retweeted
Zach Reitz@ZachReitzPhD27 Apr 2023
Replying to @BronstrupLab
correct link: pubs.rsc.org/en/content/arti…

Siderophore conjugation with cleavable linkers boosts the potency of RNA polymerase inhibitors...

The growing antibiotic resistance, foremost in Gram-negative bacteria, requires novel therapeutic approaches. We aimed to enhance the potency of well-estab

pubs.rsc.org
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Our paper on siderophore conjugation with cleavable linkers to boost the potency of RNAP inhibitors has just appeared in Chemical Science (rsc.li/41WCR4Y). Thanks a lot to Carsten, Hazel, Anna et al. for the great work! (1)
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(2) @UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @EuroMedChem
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Abstract/talk submission closes this weekend: Please register for 3rdHelmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. helmholtz-hzi.de/de/hddc2023 (1)
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(2) Major topics (novel antiinfectives, computational methods, new concepts, two free-of-charge workshops) introduced by international speaker panel. @UniHannover #chemicalbiology #antibiotics #DrugDiscovery @helmholtz_hzi @_dzif @UniHannover @tuBraunschweig @EuroMedChem
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We announce the 3rd Helmholtz Drug Discovery conference HDDC 2023 on May 15/16 in Braunschweig, Germany. Major topics (novel antiinfectives, computational methods, novel concepts, success stories) introduced by international speaker panel. helmholtz-hzi.de/de/hddc2023
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(2) Low registration fees. Please submit abstracts for short talks/posters. #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover
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We are happy to enter the second round of the SPRIND challenge for novel antivirals. Thanks also to our partners, the Hilgenfeld lab, @biotechne and the Kikkert lab @LUMC_Leiden.
Helmholtz-Zentrum für Infektionsforschung –inaktiv
@Helmholtz_HZI26 Oct 2022
In einer @SPRIND-Challenge verfolgen Forscher:innen seit dem letzten Jahr innovative Ansätze für breitwirksame antivirale #Wirkstoffe. Sechs Teams, darunter drei mit HZI-Beteiligung, werden nun für die zweite Phase mit je 1,5 Millionen Euro gefördert. 1/2 helmholtz-hzi.de/de/aktuelle…
6 Leiter:innen der geförderten SPRIND-Teams

ALT 6 Leiter:innen der geförderten SPRIND-Teams

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Optical modulation of antibiotic resistance by photoswitchable cystobactamids (M. Bronstrup et al.) @BronstrupLab onlinelibrary.wiley.com/doi/…
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Our joint paper with Doron Shabat on enzyme-activated, chemiluminescent siderophore-dioxetane probes for highly sensitive bacterial pathogen detection has been published in Angew Chem: bit.ly/376CUUu #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover
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Federica Fiorini (postdoc in our group 2018-21, natural product metabolomics) received the Darlene Solomon Award for females in mass spectrometry today: wallstreet-online.de/nachric… Congratulations, Federica!! @helmholtz_hzi @_dzif @UniHannover @DGMet #metabolomics

Nachrichten - Weitere Nachrichten | wallstreetONLINE

wallstreet-online.de
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Brönstrup Lab retweeted
Simon Hilker@hilkers_9 Mar 2022
Very proud to say that I have been awarded a Kekulé-Fellowship by @chemieverband. Thank you for supporting my research into new, exciting targeted drug conjugates @BronstrupLab @Helmholtz_HZI
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Our study on the total synthesis and the mechanism of action of armeniaspirol antibiotics just appeared in Chemical Science, almost 10 years after our discovery paper: rsc.li/3EeaILk #chemicalbiology #antibiotics @helmholtz_hzi @_dzif @UniHannover

Total synthesis and mechanism of action of the antibiotic armeniaspirol A†

Emerging antimicrobial resistance urges the discovery of antibiotics with unexplored, resistance-breaking mechanisms. Armeniaspirols represent a novel clas

pubs.rsc.org
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