Pinned Tweet
The SerTRaline for AnxieTy in adults with a diagnosis of Autism (STRATA) study aims to assess whether Sertraline reduces anxiety & improves autistic adults' quality of life.
STRATA is funded by @NIHRresearch, and receives no funding from pharmaceutical companies (1/5)
NEW 🚨 Now available as a pre-print:
"Implementation of the QuinteT Recruitment Intervention to facilitate recruitment in a placebo-controlled complex trial with autistic adults" osf.io/preprints/psyarxiv/fd…
After several years of work, over 40 researchers, clinicians, & members of our Autistic Advisory Group met at the @BristolUni Medical School for the STRATA results reveal (n.b. the main trial results are currently embargoed outside of this group)... (1/4)
... hearing from our Autistic Advisory Group about their experiences of being involved in STRATA, from initial conception all the way back in 2018 to the present day, learning the main results of the trial, and discussing potential implications for clinical practice (3/4)
The STRATA Central Research Team would like to warmly thank all presenters and attendees.
Updates on our publications will be available here: strata.blogs.bristol.ac.uk/l…
(4/4)
STRATA RCT- anxiety in autism study retweeted
As we analyse the data from the STRATA trial, you can read our publications as they are published here: strata.blogs.bristol.ac.uk/l…
Protocol paper: link.springer.com/article/10…
As we analyse the data from the STRATA trial, you can read our publications as they are published here: strata.blogs.bristol.ac.uk/l…
Protocol paper: link.springer.com/article/10…
We are now able to share that all data collection has been finalised on STRATA, and the data are now being analysed.
We are looking forward to being able to share the results of the study in 2025.
STRATA RCT- anxiety in autism study retweeted
An excellent day of shared learning with @BristolStrata and @adept_2 PPI/ autistic advisory groups and researchers at @BristolUni Botanical gardens.
STRATA RCT- anxiety in autism study retweeted
Special thanks to our @BristolStrata advisory group who celebrated their 6th year supporting all aspects of the study - from conception, now to planning dissemination. Thanks @Autistica for helping set up the group in 2018- still going strong!
STRATA RCT- anxiety in autism study retweeted
Collectively, @BristolStrata and @adept_2 have randomised almost 600 #autistic adults - the largest RCTs of #MentalHealthSupport interventions for autistic adults ever done. Both studies are in follow up stage and findings will be known by this time next year. Watch this space.
We are very pleased to share that we have achieved a retention rate of 92% for our primary outcome at 16 weeks
👇
This means that 92% of our participants in the STRATA trial returned the main questionnaire 16 weeks after enrollment. This asks key questions about participants' mental health, which will be used to determine whether sertraline is effective in treating anxiety in autistic adults
STRATA RCT- anxiety in autism study retweeted
Sertraline for anxiety in adults with a diagnosis of autism
Read the STRATA study protocol published in #Trialsjournal @BristolStrata
#ISRCTN: isrctn.com/ISRCTN15984604
trialsjournal.biomedcentral.…
WE DID IT. 4 weeks ahead of target and 12 more participants than planned (to respect commitment of those whose GP checks were in process whe we reached required 306). Now 12 months of follow up of our last participant before we work on results. More facts and figures to follow 🎊
DELIGHTED to announce that @BristolStrata has completed recruitment. 318 autistic adults randomised to sertraline/placebo. 🙏 to our participants, advisory group, trial team, sites, researchers, PIs/prescribers, funders, and supporters! @NIHRresearch @nhmrc @BrsTrialsCentre
STRATA RCT- anxiety in autism study retweeted
DELIGHTED to announce that @BristolStrata has completed recruitment. 318 autistic adults randomised to sertraline/placebo. 🙏 to our participants, advisory group, trial team, sites, researchers, PIs/prescribers, funders, and supporters! @NIHRresearch @nhmrc @BrsTrialsCentre