Led by Michael Brehm, PhD, our lab uses novel humanized mouse models to investigate type 1 diabetes & cancer in vivo @umasschan @umassdiabetes
UMass Chan Diabetes Center
Joined May 2023
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Brehm_Lab_UMassChan retweeted
Truly phenomenal meeting. Great talks and panels. Hard questions. Exciting new ideas and directions. Thank you to the Levine-Riggs Diabetes Research Symposium for bringing us all together and helping drive progress in the field! #immunologymatters #changingwhatspossible #endt1d
Brehm_Lab_UMassChan retweeted
Delighted to speak at the Rachmiel Levine-Arthur Riggs Diabetes Research Symposium! Bracing myself for an avalanche of knowledge! #immunologymatters #endt1d
Brehm_Lab_UMassChan retweeted
I got my first R01! $3M dollars. 5 y. NIAID. Huge thank you to my co-investigators Holger Russ & Michael Brehm, my lab members & the foundations who believed in me, the Medical University of South Carolina & Hollings Cancer Center for an outstanding environment.#immunologymatters
Brehm_Lab_UMassChan retweeted
The Food and Drug Administration is a critical partner in accelerating cures and therapies for type 1 diabetes. The nominee to run FDA knows first-hand how important that is. Dr. Heidi Overton, nominee to be the next FDA Commissioner, has shared with us that she lives with type 1 diabetes.
Brehm_Lab_UMassChan retweeted
Incredibly proud of @leeanadenise1, a new K99/R00 recipient, for leading this work. JCI - Immune dysregulation and stem-like CD8+ T cell enrichment in type 1 diabetes pancreatic lymph nodes jci.org/articles/view/196445
Brehm_Lab_UMassChan retweeted
Happy to share a recent publication with our collaborators at Wilmer on crystalline drug delivery to the eye to treat wet age-related macular degeneration @JCRnEDITORS!
sciencedirect.com/science/ar…
& Recent press release:
bme.jhu.edu/news-events/news…
@JHUBME @TTECJHU @HopkinsMedicine
Brehm_Lab_UMassChan retweeted
Two interdisciplinary teams of UMass Chan faculty were awarded $45,000 each from the Dan and Diane Riccio Fund for Neuroscience to support their groundbreaking research in neuroscience: direc.to/o_H4
#AdvancingTogether #neuroscience @summerbthyme @UMassChanGiving @UMass
ALT Summer Thyme, PhD, and Brian Kelch, PhD
ALT Stephanie Puig, PhD, and Andrea Reboldi, PhD
Brehm_Lab_UMassChan retweeted
Can mRNA vaccination induce tolerance rather than immunity? 🧬 Autoantigen mRNA-LNPs reduced disease in mouse models of MS and type 1 diabetes. A modular platform—but durability and safety remain preclinical.
doi.org/10.1002/advs.76382
#Autoimmunity #Tregs
Brehm_Lab_UMassChan retweeted
MD/PhD student Melanie Barbini has received an @NIH award that could have implications for multiple sclerosis and Alzheimer’s patients. Read about why she credits mentors Dorothy Schafer, PhD, and Chancellor David McManus: direc.to/oBqX #StudentSpotlight @UMassMDPhD
Brehm_Lab_UMassChan retweeted
Based on a new NOA recieved this month, we are looking for a postdoctoral fellow with solid foundation of molecular skills, creativity, and translational passion to help us develop innovative CARs for targeting discrete subsets of T cells. DM or email me if interested
Brehm_Lab_UMassChan retweeted
We are recruiting a postdoc to work on an NIH funded project to determine the role of aging and oncogene-induced stromal senescence on prostate cancer initiation and therapy resistance. See job posting and recent publication below.
ummsjobs.com/job/11591/
aacrjournals.org/cancerdisco…
Brehm_Lab_UMassChan retweeted
MISSION POSSIBLE. Overjoyed to speak at the Breakthrough T1D 2026 South Carolina Gala!
#immunologymatters #maketype1typenone
m.youtube.com/watch?v=Tc7-0a…
Brehm_Lab_UMassChan retweeted
Raymond M. Welsh, Jr. (1945–2024)—a life in viral immunology, immune regulation, and scientific mentorship @JVirology @randyb_IUSM @VargaLab @BrehmLab @CloudyMediaBlog
doi.org/10.1128/jvi.00663-26
Brehm_Lab_UMassChan retweeted
New commentary Immune-competent new approach methodologies for a hybrid future (w/ animal models) just out @NatImmunol! Congrats to co-1st authors @VanceSoares & @victorquiroz68! And co-corresponding authors @MTrapecar & @deokkim1!
nature.com/articles/s41590-0…
@JHUBME @TTECJHU
Brehm_Lab_UMassChan retweeted
Congratulations to Dr. Marcus Ruscetti of @UMassChan Medical School on receiving the prestigious 2026 Pershing Square Sohn Cancer Prize — which recognizes scientists who are accelerating cures for cancer through innovative research. #CancerResearch
🔗 brnw.ch/21x2wcV
Brehm_Lab_UMassChan retweeted
New @NIH support for #diabetes-relevant #research @UMassChan: Louis Messina, MD, has received a 5-year, $3 million grant to study how aging changes immune cells and impairs wound healing. More here: umassmed.edu/news/articles/2…
UMass Chan Medical School +1 – at Worcester, MA
Brehm_Lab_UMassChan retweeted
Summer Internship Opportunity @TheBartonCenter (Jul 5–Aug 10) offering hands-on experience in glucose monitoring, insulin management, CGMs/pumps & education while mentoring kids with #T1D. Housing/meals & academic credit. Apply/share! Other openings too! [email protected] – at Worcester, MA
