studying gene regulation shaping human brains in UNC Chapel Hill's bioinformatics and computational biology PhD program (he/him)
Durham/Chapel Hill, NC
Joined January 2009
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Bran D Le retweeted
Another awesome #neurogenomics seminar released on YouTube: catch @BrandonDLe's fantastic talk on wnt activity dependent molecular QTLs here 👇
youtu.be/LSRxOPq3Svs
@UKDRI @ImperialBrains @ImperialMed
Bran D Le retweeted
Excited to share our new preprint, where we investigated context-specific gene regulation and QTLs by stimulating 🪄⚡️ the Wnt pathway in human neural progenitor cells🧠 (co-led with two wonderful grad students @brandonDLe @jmvalone4 in @jsteinlab) biorxiv.org/content/10.1101/… 1/🧵
🧠Our paper describing common genetic effects on lithium-induced neural progenitor proliferation is out @BiologicalPsyc1!🧠 Many thanks to @JustinWolter8 @NanaMatoba @mikelaff @NilAygun8 @danliang_unc @Songlaboratory @JoePiven @MarkZylka and @jsteinlab!
sciencedirect.com/science/ar…
In our new preprint, the Stein Lab discovered common genetic variation significantly associated with human neural progenitor cell’s (hNPCs) proliferative response to Lithium! biorxiv.org/content/10.1101/… 1/9
In our new preprint, the Stein Lab discovered common genetic variation significantly associated with human neural progenitor cell’s (hNPCs) proliferative response to Lithium! biorxiv.org/content/10.1101/… 1/9
…or in fetal NPCs, genetic effects on lithium-sensitive GNL3 expression and in turn proliferation might influence neurodevelopment to affect complex brain traits like intelligence and neuropsychiatric disorder risk. 8/9
Thanks to an awesome steinlab.org team led by @jsteinlab and featuring Justin Wolter @NanaMatoba @mikelaff @NilAygun8 @danliang_unc Kenan Courtney @JoePiven and @MarkZylka ! 9/9
Check out research from the @jsteinlab this afternoon at #SfN21 from 3-4pm EST. Looking forward to discussing common human genetic variation modulating lithium-induced neural progenitor proliferation with the world!
I wrote a new piece for @UNC_SWAC about how the summer's hottest party drug owns your brain. But is it safe for children? Find out here: thepipettepen.com/music-main…
Bran D Le retweeted
Teachers shouldn’t be forced to buy their own supplies while our police departments purchase combat vehicles.
Bran D Le retweeted
I am seriously all for no weapons, but this feels like a double standard. Remember rocket launcher guy in the Raleigh Subway (sandwiches) two weeks ago protesting masks and opening barber shops? – at Durham, NC
#RaleighProtest
If you are participating in the protest, you cannot bring weapons. If you are not participating in the protest, you may not bring a weapon near the protest.
#RaleighRiots #RaleighNC #Riot2020 #RaleighPolice
Here's another thing I wrote for @UNC_SWAC about GWAS feelings: thepipettepen.com/it-gwas-th…
Bran D Le retweeted
I am thrilled to announce our 'BioBank Japan Lifestyle GWAS for dietary habits including alcohol, drinks, food consumption' is out on @NatureHumBehav ! nature.com/articles/s41562-0…