We study how circadian time is processed in the brain. We do biology, some electronics, a bit of mathematics, and just a tint of philosophy.

Taipei City, Taiwan
Joined February 2017
Braintime Lab retweeted
Excited to announce Centaur -- the first foundation model of human cognition. Centaur can predict and simulate human behavior in any experiment expressible in natural language. You can readily download the model from @huggingface and test it yourself: huggingface.co/marcelbinz/Ll…
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Braintime Lab retweeted
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Physics to John J. Hopfield and Geoffrey E. Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”
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Braintime Lab retweeted
International Chronobiology Summer School 2024 will be in Japan! Aug 5-8, Nagoya University Great opportunity for trainees to learn and connect Apply before April 30 Also join Sapporo Symposium (Aug 9-10), Asian Forum on Chronobiology (Aug 11-12)bit.ly/4cCKxzg
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"The secret of happiness is: Find something more important than you are and dedicate your life to it." Daniel Dennett (March 28, 1942 - April 19, 2024)
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Braintime Lab retweeted
It's time to stop making t-SNE & UMAP plots. In a new preprint w/ Tara Chari we show that while they display some correlation with the underlying high-dimension data, they don't preserve local or global structure & are misleading. They're also arbitrary.🧵biorxiv.org/content/10.1101/…
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In their Review, Hazlerigg @ArcticSeasonal & co discuss the impact of extreme cycles of solar illumination on the biological clocks of birds and mammals that spend all or part of their lives in the polar regions journals.biologists.com/jeb/…
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A proteomics analysis of CSF (419 AD, 187 Cont) revealed 5 AD subtypes: 1. Neuronal hyperplasticity 2. Innate immune activation 3. RNA dysregulation 4. Choroid plexus dysfunction 5. BBB dysfunction. Each subtype exhibited distinct clinical characteristics. medrxiv.org/content/10.1101/…
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Braintime Lab retweeted
Choroid plexus mast cells drive tumor-associated hydrocephalus @CellCellPress cell.com/cell/fulltext/S0092…
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Braintime Lab retweeted
細静脈のfenestration: Glymphatics/Meningeal lymphに続く第3の脳排泄機構? ・φ15-200μmの領域に分布する静脈壁上の孔 ・脳内外物質排出速度が高い部位、具体的には静脈分岐点などに集中 ・管状構造形成箇所は動的に変化 Open Access #fenstration #glymphatics #papers doi.org/10.1002/EXP.20230029
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A prominent scientist, Prof. Takao Kondo passed away. Here are the sentences (translated to Eng.) by his mentee, Prof. Iwasaki On Nov. 16, my esteemed mentor, Prof. Takao Kondo(Special Prof. at Nagoya Univ) passed away. He had been suffering from bladder cancer for a long time.
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Braintime Lab retweeted
William Bialek@wbialek20 Nov 2023
Here is another quote from John Hopfield, one of the co-authors of the cited comment ... 3/5
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🚨 PhD opportunity 🚨 Interested in cannabinoids and circadian rhythms? Still time to apply! PhD project available with me, @NeuroEndo_Ex, and @HughPiggins. findaphd.com/phds/project/fu… – at Bristol, England
🚨 PhD opportunity alert 🚨 Project available with @NeuroEndo_Ex to investigate the role of cannabinoids in circadian timekeeping and feeding ⏰️ at the @BristolUni @UoBrisPPN. Funding through GW4 Studentship 🧠🧑‍🔬 Closes 1st Nov! 🗓 Apply today: gw4biomed.ac.uk/cannabinoids…
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Braintime Lab retweeted
Imagine you're a struggling early-career pseudoscientist. Then one morning, out of the blue, you find the work you care about compared to Integrated Information Theory. That's harsh!
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Hans Krebs who identified the citric acid cycle - also known as the Krebs cycle - was born on this day in 1900. The cycle is a series of reactions that convert nutrients into other molecules with a large amount of chemical energy.
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Braintime Lab retweeted
🌅 BMAL1 & Cellular Senescence We summarize linkage between BMAL1 & factors of cell senescence including oxidative stress, metabolism & genotoxic stress response. Dysregulated & dampened BMAL1 may serve as potential therapeutic target against #aging 👇 frontiersin.org/articles/10.…
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Why we get common cold in winter? We are likely to catch the virus in summer, but we are more susceptible to develop disease symptoms in winter. Human seasonal rhythm in immune function may fight off infection in summer but not in winter. cell.com/action/showPdf?pii=…
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Braintime Lab retweeted
I designed another #LEGO set inspired by the "model" organisms of biological research! This time, it's the tiny but mighty fruit fly #Drosophila melanogaster, which researchers have used to study all manner of biological processes. 1/n
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Braintime Lab retweeted
If you're interested in the latest developments in circadian clock modelling, have a look at our news article
In #biological rhythms research, #experiments inform models as much as #simulations inform experiments. Read about a #SIAMDS21 minisymposium that explored the interface between #circadian physiology and #DynamicalSystems modeling in SIAM News Online: sinews.siam.org/Details-Page…
Colorless green ideas sleep furiously #imagen
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