@BlowerLab
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Senior Principal Investigator at New England Biolabs and Honorary Professor at Durham University. Views my own. He/him.
New England Biolabs, MA
Joined September 2020
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New preprint from the MultiDefence consortium - continuing to expand the restriction-modification landscape with MANTIS. Full info here: biorxiv.org/content/10.64898… . Well done team!
Tim Blower retweeted
You can now apply for a #ListerPrize2027 Research Fellowship.
£300,000 flexible funding to support outstanding early-career researchers within the biomedical sciences field based in the UK and Ireland.
All details 👉 lister-institute.org.uk/rese…
Tim Blower retweeted
Phages invented sgRNAs before humans!!
Obviously, for mischief… 😈
Loved seeing this story unfold!
biorxiv.org/content/10.64898…
Tim Blower retweeted
NEB researchers systematically screened 186 MazF homologs, identifying >130 active endoribonuclease with diverse sequence preferences. Read more about how Tth-MazF1 can be a powerful tool for RNA analysis in Nucleic Acids Research: doi.org/10.1093/nar/gkag338
Tim Blower retweeted
Rejection is part of science. So is resilience. 🔬
@BlowerLab and @CJStewart7 share how setbacks helped shape their careers. We don't talk about this enough.
🔁Please repost and share your own stories of defeat or bouceback. Break the stigma!
lister-institute.org.uk/news…
ALT Head and shoulder photos of Chris Steward (left) and Tim Blower (right). Both are wearing dark navy jackets and navy ties against blurred backgrounds.
Postdoc position now open in my lab at New England Biolabs. Focus is on exploring phage defence systems through biochem and structural biology. @NEBiolabs provides an academic research environment with the freedom of industry. Please take a look! 🤓🧫🧬 tinyurl.com/49phcyh6
Rel/Par superfamily toxins have yet another activity - trimming off the 16S rRNA to kill tuberculosis. Thanks again to wonderful collab with @GenevauxPierre and team, out today shorturl.at/Rm8N4 @DurBiol @NEBiolabs @izaakbeck 🤓🎊🎉
Looking for great PhD candidates! Excited to collab with Prof Mark Szczelkun at Bristol UK, studying MADS phage defence. This will be a CASE studentship including research visits to New England Biolabs HQ in MA, USA 🤓 @NEBiolabs shorturl.at/KZGup deadline 3rd Dec
RptR is a new addition to the growing collection of phage defence-associated transcriptional regulators. Congrats to @YugengZ @TangLabOxford @_MarionSchuller @IvanAhelLab and thank you, it was a pleasure to help out the study! @NEBiolabs. academic.oup.com/nar/article…
Latest BREX story from the lab - turns out there is a nuclease after all! Congrats to Jenny Readshaw and the whole team, including wonderful collabs Barry Stoddard, Brett Kaiser and @DarrenSmithdx. @NAR_Open @NEBiolabs @DurBiol academic.oup.com/nar/article…
Tim Blower retweeted
We are delighted to host Professor Tim Blower @BlowerLab as keynote speaker to our MID symposium
@WarwickLifeSci
Date: 20th of June Venue: GLT1 We invite MBio, PhD students and Postdocs to submit abstracts for posters and talks by 11th of June to
@CRodriguesLab
Tim Blower retweeted
For those of you who approached me at @MicrobioSoc #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
The lab is now up and running at New England Biolabs @NEBiolabs! I'm looking for a postdoc to study phage defence systems. If you'd like the academic freedom to publish but the resources of industry, then take a look 🤓😃 neb.wd5.myworkdayjobs.com/en…
Super opportunity to join Giusy in Glasgow!
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
Tim Blower retweeted
The final version of our Serratia paper is now out! Congrats to @TomCX99 and (X-less) Suraj, and a big thank you to @BlowerLab and @StephenRG97. tinyurl.com/3vnyvufa
New pre-print from the lab, led from (for now Twitter-less) star-RA Tom Cummins. If you did receive his PhD application, you do not want to miss this chance, Tom is a star!
As always, fun collaboration with the amazing @BlowerLab and @StephenRG97
Tim Blower retweeted
Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow @UofGSii ! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!
Tim Blower retweeted
Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date).
@JohnInnesCentre @DurhamU34989 @MCB_UJ
Tim Blower retweeted
Thrilled to share my latest postdoc paper published in
@NatureComms
NTase toxin targeting serine tRNA 3'-ends by CMP addition in M. tuberculosis H37Rv. Thanks to all the co-authors,
@GenevauxPierre
@BlowerLab
@ONeyrolles
rdcu.be/dZle4
Tim Blower retweeted
When experiments don’t work... build a phage costume! 🎃
Happy PHAGEOWEEN!!! 👻🧬#Teamwork