Clinical Perfusion Scientist • 🫀🫁🫧 • Prev ICU & ECMO Nurse • Interests in CFD & resuscitation • 🏳️‍🌈

London, England
Joined August 2017
Kinetics of sevoflurane vaporized directly in #ECMO membrane lung  🔬ex-vivo trials using circuits primed with Ringer’s lactate; sevoflurane vaporized at concentrations of 1–8% with SGF of 1–10 L/min.  💨 sevoflurane effectively crossed PMP membranes, rapidly reaching reproducible peak concentrations to values consistent with clinical targets for deep sedation; clearance increased significantly with higher SGF  ⚠️ environmental concentrations well below occupational safety thresholds  Delivering sevoflurane vaporized directly into ECMO circuits feasible/safe alternative sedative strategy. These results provide a robust foundation for translating this into pilot clinical trial aimed at optimizing ECMO sedation with inhaled sevoflurane in patients with severe ARDS. 🔓 rdcu.be/fk2xq
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UK multisociety consensus statement on the emergency management and resuscitation of patients with left-sided Impella support 🫀Recognition of cardiac arrest 🏥 Team structure 🕵️ Early troubleshooting heart.bmj.com/content/early/…
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#ECMO following acute type A aortic dissection repair? 🔍 SR/MA 🪦 successful weaning 48.3%, but high in-hospital mortality = 72.4%; late mortality 5.8% per 100 pt/y 🫘 AKI requiring CRRT 60.5% 🧠 neuro complications due to stroke 24.4% 🦵🏻 limb ischemia 7.6% 🩸 bleeding requiring reoperation 29.2% #ECLS may be reasonable. Despite high morbidity and mortality (comparable with other PC-ECLS), myocardial recovery may be achieved with careful patient selection: young patients better candidates; pre-ECMO lactate peak appears strong predictor for mortality. @asaiojournal 🔗 bit.ly/4osNa
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The @ERC_resus 2025 Guidelines are here! These guidelines have helped inform the RCUK 2025 Guidelines which will be published on Monday 27 October at midday.
👏 The Wait is over 🚀 The 'ERC 2025 Cardio Pulmonary Resuscitation Guidelines' is Released. 🫀 Click the link to know more 👉 erc.edu/news/2025-erc-guidel… #ERC #CPR #Guidelines2025 #ERCGuidelines #savelives #RESUS25
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British societies guideline on management of emergencies in patients on ECMO 🫀Recognition of cardiac arrest 🏥 Team structure 🕵️ Early troubleshooting @BritishCardioSo @FICMNews @ICS_updates @BACCNUK @SCTSUK @BSHeartFailure @ResusCouncilUK @ACTACCUK link.springer.com/article/10…
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The @ELSOOrg ECMO Bedside Guide is now available globally FREE open access for everyone interested in #ECLS! Honoured being among leads for 📋 Checklists & ⚠️ Panic button sections Other topics ⚖️ assess candidacy 📦 equipment 🧮 calculators 💉 medications 📚 resources 📱 bit.ly/ELSOBedsideGuideA
📢 2️⃣ years & > 1️⃣0️⃣0️⃣ people from around ELSO world came together to create something useful for our community: ELSO's ECMO Bedside Guide, free, intended to be useful to everyone interested in #ECMO. We are thrilled to make this available globally! 📱 bit.ly/ELSOBedsideGuideA
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In Organ Donation Week, confirm your decision on the NHS Organ Donor Register, and share your wishes with your family and friends. You could save a life. Go to organdonation.nhs.uk #OrganDonationWeek
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Sharing this fab myth-busting infographic from @THINK__AORTA in the last ten mins of this year’s #AorticDissection Awareness Day! 🫀🚑 @ThinkAorta @AorticDissectUK @AorticDissectCT
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Coronary, renal & cerebral perfusion of VA #ECMO + #IABP in refractory cardiogenic shock 🔬in vitro study 🫀hemodynamic effects depend on CO, HR, site of #ECLS arterial cannulation If severe low CO, axillary artery (vs femoral) cannulation + IABP showed greatest benefit in terms of coronary/cerebral flow but renal perfusion negatively affected. #FOAMcc #FOAMecmo @asaiojournal 🔓 bit.ly/4jnn7jQ
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🎥 Recording of the webinar: Hot topics in NRP, perfusionist’s perspective, a joint @The_EBCP & @EuroELSO event, is now available, open access #FOAMcc at 🎥 youtube.com/watch?v=RPd5nugH… We discussed about: 🔥 Who should manage NRP 🔥 The circuit: #ECMO, #CPB or hybrid? 🔥 What the ideal perfusion targets? How to monitor perfusion? 🔥 Education & training #EuroELSOwebinar
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One important point about differential hypoxemia: People often think the R radial sat will be the first site to show drop. This isn’t true. The first vessel to experience hypoxemia It’s the coronary arteries. Watch for cardiac ischemia as a sign of differential hypoxemia!
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2024 @EACTS @EACTAIC @The_EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery: 🎓 training, education & service delivery 🛠️ heart-lung machine hardware 📦 CPB disposables 🖥️ monitoring 🫀🧠🫘🫁 organ protection ⚙️ preparation for CPB 🩸procedures during CPB 🔍 CPB for specific techniques & specific situations during #CPB ✂️ separation from CPB 🚧 gaps in knowledge 🔑 key messages Open access 🔓 bit.ly/3X06hz0
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Out now! Ep3 of the #THINKAORTA podcast re-unites survivor Anne Cotton with Dr. Martyn Bell, who diagnosed her acute #AorticDissection in @RoyalDevonNHS Barnstaple Hospital Emergency Department 9 years ago. Watch the full story here: youtu.be/MvHB_T34N9Q?feature… – at Norwich, England
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Blood cell salvage & transfusion requirements after decannulation from VV #ECMO 🔎 841 pts, 2 🇬🇧 centers 🩸BCS decreased PRBC transfusion, no changes in inflammatory & coagulation markers, nor in transfusion of other blood products in 2 days 🔓 rdcu.be/d2DRy
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Critical Care? Mastered it. ✅🎓🏴󠁧󠁢󠁳󠁣󠁴󠁿🥂 Endless thanks to the @Ed_CritCare_On & @RCPEdin teams for three wonderful years culminating in a fabulous graduation at McEwan Hall today.
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Many thanks to the @RCPEdin for a wonderful MSc Critical Care Graduates’ Reception this evening 🥂@Ed_CritCare_On
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Pristine views en route to Edinburgh for the @Ed_CritCare_On @RCPEdin MSc Critical Care graduation this weekend! 🎓
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Normothermic machine perfusion is increasingly used to approximate human physiology, preserve organs outside the body, provide dynamic graft assessment. Although NMP application is relatively new, its concept, foundation, development can be traced back to 1930s: 💡prototypical experimental surgeon-scientist 🩸Carrel & Lindbergh perfusion device 📜 legacy 💡 Carrel & Lindbergh’s lasting impression on NMP @asaiojournal 🔗 loom.ly/pOGycXI
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Thrilled to be finishing the @Ed_CritCare_On MSc Critical Care programme with distinction after three long but fabulous years! All thanks go to the @Ed_CritCare_On & @RCPEdin teams, my clinical colleagues & of course @billyjoefryer for tolerating my endless requests and demands.
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