Majumdar Lab. Fun with B cells and RNA. Here to help anyone doing science.
Burlington, Vermont
Joined May 2020
- Tweets593
- Following754
- Followers386
- Likes5.8K
Dev Majumdar retweeted
I'm not referring to any particular tool. I'm referring to how scientists are presenting their science and that of others. It's getting so bad that it's impossible for any non-domain expert to believe anything anyone claims. This is extremely troubling for credibility of science.
Dev Majumdar retweeted
Excellent example of the core issue I was trying to get at wrt "virtual cells" - optimizing a prediction objective will not necessarily provide an accurate representation of physical or biological phenomena. It's extremely important to be very clear about this. 1/
It was a dark time in the pre-Benchling era in my "ecosystem." Worth noting that people who say this exist. Long live @benchling and props to their VCs.
Dev Majumdar retweeted
TIL the best way to spread misinformation is by presenting it in LaTeX
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Dev Majumdar retweeted
✅ @Harraz_Lab has an open lab technician position ✅
Highly motivated individuals with relevant experience are encouraged to apply.
uvmjobs.com/postings/75843
📢 We explore brain blood flow, physiology and pathophysiology of ion channels. Learn more harrazlab.com
Plz RT
ALT view from the lab!
Dev Majumdar retweeted
Fascinating study @NatureComms from @RohacsTibor showing that phosphatidic acid can regulate PIEZO2, the mechanosensitive ion channel — and so glad to see yet another application “in the wild” of optoPLD, @ReikaTei’s optogenetic membrane editor for phosphatidic acid! #lipidtime
I always had a hunch that phosphatidic acid regulates ion channel function. This paper from @RohacsTibor and colleagues shows this nicely.
nature.com/articles/s41467-0…
#IonChannels
The best clickbait is google images molecular clickbait. How else do you read a calcium signaling paper with a "Parabolic Flight Experimental Design" methods section. mdpi.com/2227-9059/10/1/138
Dev Majumdar retweeted
Tried to express and purify your own Tn5 transposase only to run into stability or activity issues? Our new @biorxiv preprint describes OpenTn5: a robust, high-yield protocol for producing a stable pG-Tn5 transposase fusion. Spearheaded by @Jan_Soro.
biorxiv.org/content/10.1101/…
Incredibly cool. And now all I can think about is making homemade flag M2 antibody...
Our paper @MFPronker @JWBglnk on the structure of anti-FLAG-M2 in complex with the FLAG-peptide (DYKDDDDK) is now peer reviewed @JMolBiol 🎉
sciencedirect.com/science/ar…
Dev Majumdar retweeted
We posted a new preprint (biorxiv.org/content/10.1101/…). We've been thinking about how to characterize TF function. One challenge is that function and occupancy are difficult to disentangle. We use a simple model and a simple system to test how promoter features change function.
Dev Majumdar retweeted
We are looking for postdocs interested in working on this project to engineer polyclonal vectored antibody delivery!
I think this is my new favorite African livestream. Currently two lions playing as a rhino dozes nearby. youtube.com/watch?v=fZ6mUUZJ…
I love it. If we can agree Zirp was necessary & sufficient for the onset of the trend, is Zirp required for sustained maintenance?
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