All opinions are mine only.
Joined August 2012
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#SGLT2inhibitors vs #GLP1RAs in #BipolarDisorder with #CKD. Similar risk of Kidney replacement therapy in long-term. SGLT2is were in-fact superior among people with #CKD and #DM
sciencedirect.com/science/ar…
Balwinder Singh retweeted
GLP-1s and lithium: what could go wrong? In a new report from @MayoClinic, the authors discuss a case of severe #lithium toxicity requiring hemodialysis after #tirzepatide initiation in a patient with bipolar I disorder.
🎧 jcpjournal.libsyn.com/tirzep…
📰 ovid.com/jnls/psychopharmaco…
Balwinder Singh retweeted
A minute with Dr Singh as he explains the connection between thyroid function and depression.
bit.ly/4yb8S9q youtube.com/watch?v=OKH9PuYh…
SGLT2i users had a higher cardiovascular disease burden, whereas GLP-1 RA users were generally less medically complex and more likely to have overweight or obesity.
Balwinder Singh retweeted
In this longitudinal cohort study, abnormal thyrotropin levels were consistently associated with a significantly increased risk of clinically relevant depression across all temporal windows.
mayocl.in/4pYniqN
#BipolarDisorder #OlderAdults
Kudos to Dr. Asir & Dr. Al-Soleiti @majdsleitii for their outstanding contribution. #EvidenceBased #pharmacotherapy for this growing population @MayoPsych @EMC_ISBD4 @ISBD4 @BD2Discoveries
Proud to have co-authored this paper with my good friend and colleague Bashar and my mentor Dr. Singh, on treatment of bipolar disorder in the elderly..
link.springer.com/article/10…
The findings support the use of benzodiazepines as a first-line treatment option, the researchers said, adding that 88% of patients in this analysis received benzodiazepines either alone or in combination with another treatment. ow.ly/uRfj50YFeeF
Balwinder Singh retweeted
Excited about our latest publication in Bipolar Disorders! 🎉 SGLT2 inhibitors were associated with improved kidney function trajectories in lithium-treated patients 💊📈
Grateful to @MayoPsych, @BalSinghMD & all collaborators.
🔗 onlinelibrary.wiley.com/shar…
Prescribing or taking lithium + starting a GLP-1 agonist?
⚠️ Monitor lithium levels closely—GLP-1s may alter absorption and clearance.
#PsychiatryPearls #GLP1 #LithiumSafety
Glad to have published this alarming case series, where semaglutide initiation was followed by increased lithium level or toxicity, despite no clear side effects or decreased intake (in 2/3 cases).
Thanks to @DrSola1, @JGLPharmD, @BalSinghMD
@MayoPsych
journals.lww.com/psychopharm…
Balwinder Singh retweeted
Balwinder Singh, MD, MS, @BalSinghMD presented his collaborative work, "Sodium-glucose Cotransporter 2 inhibitors for Lithium-Associated Kidney Dysfunction in Mood Disorders: A Historical Cohort Proof-of-Concept Study" at #ISBD2025 @ISBD4 #Lithium #MoodDisorders
Balwinder Singh retweeted
🧠 Join the NNDC Best Practices!
For more information click on the following link:
nndc.org/2025-best-practices…
Balwinder Singh retweeted
Bipolar disorder affects over 40 million people worldwide. Yet diagnosis remains challenging, causing delays in effective treatment.
Recent advances in understanding & emerging therapies offer hope for more precise, patient-centred care.
Find out more: hubs.li/Q03GjB9W0
Balwinder Singh retweeted
A new study found that the loss of lithium, a naturally occurring element in the brain, could be an early sign of Alzheimer’s and a powerful driver of the disease.
Here’s a look at what lithium has been able to treat and how its being researched: wapo.st/4ouuucV
Balwinder Singh retweeted
Bipolar disorder affects over 40 million people worldwide. Yet diagnosis remains challenging, causing delays in effective treatment.
Recent advances in understanding & emerging therapies offer hope for more precise, patient-centred care.
Find out more: hubs.li/Q03zfhb00
Balwinder Singh retweeted
webmd.com/depression/news/20…
A new WebMD article featuring our recent review article on anhedonia. Thanks again to @BalSinghMD for his mentorship!
🔍 New in @TheLancet: A Comprehensive Update on #BipolarDisorder
Led by BD² investigator @BalSinghMD, this is a must-read for those working to improve outcomes for individuals with #bipolar disorder.
📖 Read the paper: authors.elsevier.com/a/1lTur…
▶️ Hear from @BalSinghMD:
Balwinder Singh retweeted
An overview describes anhedonia’s significance as both a symptom and diagnostic marker, prevalence, and pathophysiological underpinnings. bit.ly/4ipvTNP
RDoC depression phenotypes offer new insights into ketamine’s rapid antidepressant effects in TRD—shaping the future of precision psychiatry."
#RDoC #Ketamine #TRD #BioK @NNDC_official @MayoPsych
sciencedirect.com/science/ar…
Balwinder Singh retweeted
Monotherapy with antidepressants or antipsychotics in individuals with bipolar disorder was associated with increased risk of hospitalization for depression. ow.ly/NVFR50VqyFv
