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JCP keeps clinician-scientists and trainees up-to-date on the latest clinical developments in psychopharmacologic agents. Our podcast: https://xitter.cf/t.co/iXWmMM85rV
Lippincott Williams & Wilkins
Joined January 2011
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Do #pharmacogenomic tests improve patient-centered outcomes in #depression? This study found similar improvements in well-being and symptoms over 12 months regardless of whether clinicians had access to combinatorial pharmacogenomic testing results.
🔗 ovid.com/jnls/psychopharmaco…
Psychopharmacology is more than matching diagnoses to guidelines. RCTs and guidelines inform treatment, but they do not replace clinical judgment. Our podcast discussion of a new editorial focuses on this topic.
🎧 jcpjournal.libsyn.com/interm…
🧾 ovid.com/jnls/psychopharmaco…
GLP-1s and lithium: what could go wrong? In a new report from @MayoClinic, the authors discuss a case of severe #lithium toxicity requiring hemodialysis after #tirzepatide initiation in a patient with bipolar I disorder.
🎧 jcpjournal.libsyn.com/tirzep…
📰 ovid.com/jnls/psychopharmaco…
New pharmacovigilance data suggest that #olanzapine and #clozapine may be more strongly associated with pulmonary embolism than other antipsychotics. Whether this reflects medication effects, underlying severe mental illness, or both remains unclear.
🔗 ovid.com/jnls/psychopharmaco…
The Journal of Clinical Psychopharmacology is building a presence on @Bluesky, and we’d love for our @X community to be part of it.
Follow us on Bluesky Social for early updates, featured research, and insight into psychopharmacology trends. 📲 psychopharm.bsky.social
Could psychiatry be looking beyond #neurons? A new review argues that #astrocytes and neuron-glia networks may play a central role in mental illness and discusses how findings from #GLP-1 therapies challenge traditional neurotransmitter-based models.
🔗 ovid.com/jnls/psychopharmaco…
For patients with treatment-resistant #schizophrenia who refuse oral clozapine, intramuscular #clozapine may provide a bridge to treatment. A systematic review found successful transitions to oral therapy were commonly achieved within days.
🔗 Read more: ovid.com/jnls/psychopharmaco…
Can boosting #serotonin #synthesis improve outcomes when SSRIs are not enough? Our latest review and podcast explore five decades of evidence for serotonin synthesis amplification as an #augmentation strategy.
🎧Podcast: jcpjournal.libsyn.com/seroto…
📜Article: journals.lww.com/psychopharm…
Obsessive-compulsive symptoms are common and difficult to treat in #bipolar disorder. A new RCT found that adjunctive #memantine significantly reduced #OCD symptom severity, supporting further study of #glutamatergic approaches in BD-OCD.
🔗Read more: ovid.com/jnls/psychopharmaco…
Toward #precision #psychiatry: In older adults with depression, lower venlafaxine metabolite exposure and lack of early response predicted poor outcomes, but biomarker-informed models performed similarly to clinical predictors alone.
🔗 Read more in JCP: ovid.com/jnls/psychopharmaco…
What do we know about #cariprazine during #breastfeeding? Analysis of milk samples from 5 lactating women found low infant exposure, though reports of infant lethargy and concerns about metabolite accumulation warrant further study.
🔗Read more in JCP: ovid.com/jnls/psychopharmaco…
📢 Our September/October 2026 issue (Volume 46, issue 5) is now available online: ovid.com/jnls/psychopharmaco…
High-dose #propranolol is sometimes used to treat severe aggression and self-injurious behavior in #autism spectrum disorders. In a retrospective review of 52 patients receiving up to 1200 mg/day, no serious cardiologic adverse events were observed.
🔗 ovid.com/jnls/psychopharmaco…
A reminder that #serotonin syndrome can masquerade as delirium in older adults. This case highlights the dangers of serotonergic #polypharmacy and the importance of coordinated prescribing across specialties.
Read more in JCP: 🔗 ovid.com/jnls/psychopharmaco…
Can #cognition improve during routine treatment for #bipolar I disorder? A prospective cohort study found significant gains in both self-reported and objectively measured cognition over 3-4 months, regardless of medication regimen.
Read more in JCP: 🔗 ovid.com/jnls/psychopharmaco…
Journal of Clinical Psychopharmacology retweeted
Pleased to share our new systematic review and meta-analysis, published in the Journal of Clinical Psychopharmacology, on alpha-lipoic acid as an adjunctive therapy for schizophrenia.
pubmed.ncbi.nlm.nih.gov/4253…
Grateful to all co-authors for their rigorous and thoughtful collaboration.
@JCPjournal
Can boosting #serotonin #synthesis improve outcomes when SSRIs are not enough? Our latest review and podcast explore five decades of evidence for serotonin synthesis amplification as an #augmentation strategy.
🎧Podcast: jcpjournal.libsyn.com/seroto…
📰Article: journals.lww.com/psychopharm…
How common is #liver disease in patients with schizophrenia receiving #antipsychotics? A study using FibroScan found that one-third of patients had MASLD and hepatic steatosis, and more than one-quarter had hepatic fibrosis.
🔗 Read more in JCP: ovid.com/jnls/psychopharmaco…
With no FDA-approved medications currently available for #methamphetamine use disorder, new research offers encouraging safety data for #mirtazapine.
Read more in JCP: 🔗 ovid.com/jnls/psychopharmaco…
Can high-dose #propranolol be used safely in #autism spectrum and related developmental disorders? In a retrospective review of 52 patients receiving doses up to 1200 mg/day, investigators found no serious cardiac adverse events over 8 years.
Read more: 🔗 ovid.com/jnls/psychopharmaco…
