Laboratory of Salvador Aznar-Benitah. Stem cells and cancer lab at @IRBBarcelona. Account shared between all lab members.🧬🧫🔬
Joined June 2021
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New preprint from the lab out now!!💥💯
Our new manuscript is now available as a preprint!⛅️
biorxiv.org/content/10.1101/…
1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵
Check out our latest methods paper for studying protein palmitoylation in mammalian cells. Great collaborative work between the Fendt Lab (@vib_ccb) and @AznarLab (@IRBBarcelona), led by @anke_vandekeere and @Miguel_MartinP!! authors.elsevier.com/a/1kZOH…
Check out our lastest review on all things circadian clock communication, out this week in NRMCB!
Circadian clocks constantly communicate to preserve tissue homeostasis, but ageing compromises the mechanisms that enable this crosstalk. Want to learn more? In our new review, @JacobSmithSci, Pura, Salva and take a dive into all things clock communication nature.com/articles/s41580-0…
@GuillemPosas and @claudiabigas7, presented their work at Artificial Intelligence: Reshaping Biomedical and Healthcare Research at Nanyang Technological University, Singapore! 🌍 Excited to share how AI is transforming biomedicine. @ENABLE_conf @FEBSnews #AIinMedicine
We're proud of @claudiabigas7 for presenting her project on the epigenetic influence of early-life exposure to a high-fat diet on liver disease at the #Epigen24 @Fusion_Conf ! 🧬 Big thanks to the organizers for giving us this fantastic opportunity!
Our talented PhD student @GuillemPosas lead his first Preclinical Models of Cancer node seminar at @IRBBarcelona ! His talk on The role of Schwann cells in aging-dependent tissue decline was inspiring! 💡🌟
Congratulations to @MajemCavalle for delivering an inspiring talk as an invited speaker at the Cachexia mini-symposium, Barcelona! 🧬✨ @idibell_cat
Open position for Lab Manager in our lab!! Check out the offer below⬇️
📢 We are #hiring a Lab Manager for our Stem Cells & Cancer group (@AznarLab)!
Apply here ➡️shorturl.at/enQ34
#IRBJobs #Jobs #ScienceJobs #LabManager
Please head to this link for a deep dive into the content and conclusions of the brain-skin story nitter.cf/Mortimert91/status/178… @Mortimert91
Nearly five years and many a sleepless night later, it’s a pleasure to share my postdoctoral work exploring brain-skin circadian communication! So what did we do, what did we discover and what conclusions can we draw? 🧵1/17
cell.com/cell-stem-cell/abst…
@AznarLab @CellStemCell
Tremendous contributions also from Carmelo Laudanna, Oleg Deryagin, @GuillemPosas, @JacobSmithSci, Elisa García-Lara, @leo_assis13, Isabel Hyde, Henrik Oster and many others!
These studies has been a superb, productive collaboration between ourselves and our friends over at the Muñoz laboratory.
We are thrilled to share with you all our most recent studies dissecting circadian clock communication in the muscle and skin!
Brain-skin cell.com/cell-stem-cell/abst…
Brain-muscle science.org/doi/10.1126/scie…
Yesterday @claudiabigas7 and @JBonjoch7 presented their respective work at the 1st PhD Day organized by and for IRB PhD students. The event was a success, with lots of cool science and time for fun too. Congrats to all🥳
We're happy to see that one of the images from our recent skin aging paper was selected as image of the month!!
🎨 nature.com/articles/s43587-0…
📸 Introducing our #July #ImageoftheMonth: "Endless Roads of Differentiation"!
🔬By @JBonjoch7, @palomasocas & @guiosol (@aznarlab), this outstanding image shows #immunofluorescence of adult mouse skin, revealing the process of epidermal cell differentiation.
🌞Happy July! 🌊⛱
Even though our cover wasn't selected, we wanted to thank the very talented @rebeca_santano for this artwork! It depicts "aged" cells with surrounding IL-17, and "adult" cells with antibody-bound IL-17 🎨
📄: nature.com/articles/s43587-0…
Check out @guiosol in the local news talking about our latest paper!
👉doi.org/10.1038/s43587-023-0…
👇
📺La Dra. Guiomar Solanas del laboratori de Cèl·lules Mare i #Càncer de l'#IRBBarcelona parla a @IB3televisio sobre el recent article a @NatureAging sobre la proteïna IL-17 i el seu paper en l'#envelliment de la pell.
#IRBScience @guiosol @AznarLab
Have you checked out our latest paper already?! What are you waiting for💥
Online now! Solá, Mereu, and colleagues describe a chronic inflammatory state in the aging murine skin that is characterized by IL-17 production by dermal lymphoid cells, a potential therapeutic target to protect against skin aging. @AznarLab doi.org/10.1038/s43587-023-0…