@Amurtab

Pharmacist, Postdoctoral Fellow @UAlberta_Pharm 🇮🇷🇨🇦

Joined December 2015
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This will likely be my last thread here as I’m moving over to Bluesky (bsky.app/profile/jussherlab.…), but wanted to share exciting work from former PDF @Amurtab @UAlberta_Pharm ; cell.com/iscience/pdf/S2589-…
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Super excited for @SaedChristina for landing the @CIHR_IRSC postdoctoral fellowship and finishing her PhD at the same time! Way to go, so proud of you!
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New systematic review and meta-analysis: RCT data from 16,839 placebo- and 16,550 semaglutide-treated patients and 13,330 real-world study patients show no association between semaglutide and pancreatic cancer, thyroid cancer or all neoplasms👍🏻 sciencedirect.com/science/ar…
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Now free to read ⁦@NatRevCardiol⁩ #heartdisease #diabetes #T2D #obesity #heartfailure ⁦@JussherLab⁩ nature.com/articles/s41569-0…
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I’m pleased to share our recent review published in @NatureCVR about Ketones and the Cardiovascular System. A pleasure working on this with my friend and colleague, Gary Lopaschuk @LopaschukLab @UAlberta_FoMD @DyckLab nature.com/articles/s44161-0…

Ketones and the cardiovascular system

Nature Cardiovascular Research - Lopaschuk and Dyck review the bioenergetic and signaling effects of ketones on the cardiovascular system and discuss the potential application of ketones for...

nature.com
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Thank you @CIHR_ICRH for giving me this opportunity to pursue my passion and make a difference. This would have been impossible without the support of my brilliant mentor. I am forever grateful to @JussherLab for reshaping me into the person and researcher I am today.
John R. Ussher@JussherLab6 Feb 2023
some very exciting news to share that @Amurtab received a fellowship from @CIHR_IRSC and we look forward to sharing his current work on developing new pharmaceutical agents that decrease #ketone #oxidation to promote #glucose_lowering in the future!
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It’s been a while since I used Twitter for this, but our lab is looking to recruit a new #postdoc, if anyone is interested in studying either #cardiac or #skeletal_muscle #energy #metabolism in #obesity or #rare_genetic_diseases, please DM me and others please RT
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RESEARCH PROJECT: Development of succinyl-CoA:3-ketoacid CoA transferase (SCOT) inhibitors for the treatment of Type 2 diabetes AMIRHOSSEIN TABATABAEI Postdoctoral Fellow Learn more about Amirhossein's Research: bit.ly/3ONF0KS #diabetesawarenessmonth #ualberta
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RESEARCH PROJECT: Myocardial Ketone Body Oxidation as a Therapeutic Target for Diabetic Cardiomyopathy "Therapies specifically designed to treat diabetic cardiomyopathy or diabetes-related heart failure are exceptionally limited." bit.ly/3iphvvo #DiabetesAwarenessMonth
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"We believe that finding a better target for diabetic heart disease with less potential for adverse effects would improve the quality of life of people with diabetes." - KESHAV GOPAL, Research Associate Learn More: bit.ly/3gJ9wsR #DiabetesAwarenessMonth #UAlberta
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Just got back from #Seoul and missed this coming online, but really excited to share our lab’s latest research looking at the possible #repurposing of #diphenylbutylpiperidines for the treatment of #T2D doi.org/10.2337/db22-0221 Congrats to @amurtab !!!

The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in...

Despite significant progress in understanding the pathogenesis of type 2 diabetes (T2D), the condition remains difficult to manage. Hence, new therapeutic

diabetesjournals.org
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Online now! GTTs and ITTs: aim for shorter fasting times dlvr.it/S6tlK3
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I have to admit when first learning of the Michaelis-Menten equation decades ago (in Zimbabwe), my mental image was of two white guys. Never stopped to even consider a woman biochemist from this era! Pretty sure the teacher had no idea either.
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Congratulations to our @AlbertaDiabetes members and their teams who were awarded funding for the 2021 Spring @CIHR_IRSC Project Grant competition! Read the full results cihr-irsc.gc.ca/e/52598.html
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Really excited to share our manuscript "Rare variant contribution to human disease in 281,104 UK 2 Biobank exomes" now published in @Nature nature.com/articles/s41586-0… @AstraZeneca @kerencarss @DrAndrewHarper @ruth_march @SlavePetrovski @uk_biobank

Rare variant contribution to human disease in 281,104 UK Biobank exomes

Nature - The authors analyse rare protein-coding genetic variants for association with 18,780 traits in the UK Biobank cohort.

nature.com
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In the latest issue! An atlas of protein-protein interactions across mouse tissues dlvr.it/S4S3DZ
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This is how a vaccine works and it is genius. xitter.cf/neverseentit/status/14…
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Emma Allen-Vercoe: “You are not human. microbes outnumber human cells 1.3:1. But for a brief moment after a bowel movement, you are slightly more human.” @EmmaAllenVercoe @WomenMicrobes #WomenMicrobes2019 #womenshealth #probiotics
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Our new paper @Nature is an epic tale of obesity, calories, gut microbes, and C. difficile. Trainees interested in contributing to the sequel should ping @JordanBisanz to join his new lab @PennState bisanzlab.github.io nature.com/articles/s41586-0…
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