@AllThingsPhages

comments about actual #phage research, projects and selected papers. #bacteriophages #amr #phagetherapy

Joined June 2021
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AllThingsPhages retweeted
Paul Bollyky@bollykySep 21
I'm excited to share our newest publication on hydrogel wound dressings to deliver phage therapy. We show that topical, sustained phage delivery using hydrogels is more effective than intravenous phage delivery. Check it out here: rdcu.be/yrPRzjdC8qLa
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Sebastian Leptihn@LeptihnLabJul 3
New preprint on hypervirulent #Klebsiella #Phage 🔹 2 phages, shared receptor 🔹 Cocktail can be antagonistic 🔹 Order-aware sequential therapy limits resistance and improves efficacy Happy to be part of this study 😊 doi.org/10.64898/2026.06.10.…
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Illuminating the newly produced viruses within the virosphere with bioorthogonal noncanonical amino acid tagging and single-virus genomic sequencing technologies academic.oup.com/ismecommun/…

Illuminating the newly produced viruses within the virosphere with bioorthogonal noncanonical amino...

Abstract. Marine viruses impact biogeochemical cycles through cell lysis, releasing organic matter and nutrients that fuel ocean productivity. Identifying

academic.oup.com
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AllThingsPhages retweeted
Paul Bollyky@bollykyJun 3
Good news! The @NIH and NIAID have created the Centers for Accelerating Phage Therapy to Combat ESKAPE Pathogens (CAPT-CEP). Here at @StanfordDeptMed we are so excited to be part of this program with @PittTweet and @GladstoneInst
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Benchmarking of shotgun sequencing depth reveals the potential and limitations of shallow metagenomics and strain-level analysis dlvr.it/TS8TVG #MicroSky

Benchmarking of shotgun sequencing depth reveals the potential and limitations of shallow metagen...

Nature Microbiology - A comparison of sequencing of complex mock communities performed at multiple depths and analysed using different methods establishes minimum standards that can ensure the...

nature.com
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AllThingsPhages retweeted
Cell@CellCellPressApr 1
Now online! Phages communicate across species to shape microbial ecosystems dlvr.it/TRq3qC

Phages communicate across species to shape microbial ecosystems

Gallego-del-Sol et al. show that arbitrium-coding phages can sense non-cognate peptide signals from other phages to regulate lysis-lysogeny decisions. This crosstalk affects lysis-lysogeny outcomes...

cell.com
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AllThingsPhages retweeted
Sebastian Leptihn@LeptihnLabMar 31
We often hear: “Phage therapy is not approved.” But approval follows research, not the other way round. We explore alternatives like tailocins and built TattleTail, a tool to detect pyocins in P. aeruginosa genomes. biorxiv.org/content/10.64898…
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AllThingsPhages retweeted
Stephen Turner@strnrMar 20
PeGAS: a versatile bioinformatics pipeline for antimicrobial resistance, virulence and pangenome analysis academic.oup.com/bioinformat… 🧬🖥️🧪 github.com/liviurotiul/PeGAS
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AllThingsPhages retweeted
Tim Blower@BlowerLabMar 20
Postdoc position now open in my lab at New England Biolabs. Focus is on exploring phage defence systems through biochem and structural biology. @NEBiolabs provides an academic research environment with the freedom of industry. Please take a look! 🤓🧫🧬 tinyurl.com/49phcyh6
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Promising #phage 🦠 #antibiotic 💊combination prevents evolution of resistance in clinical Klebsiella isolates in vitro: nature.com/articles/s44259-0…

Phage-meropenem synergy against OXA-48-producing Klebsiella pneumoniae clinical isolates

npj Antimicrobials and Resistance - Phage-meropenem synergy against OXA-48-producing Klebsiella pneumoniae clinical isolates

nature.com
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Bacteriophage-based technologies for wastewater treatment and biogas production: Current evidence and technological prospects. onlinelibrary.wiley.com/doi/…

Bacteriophage‐Based Technologies for Wastewater Treatment and Biogas Production: Current Evidence...

Bacteriophages are emerging as precision tools for engineering microbial consortia in wastewater treatment and biogas production. This review outlines application strategies, ecological mechanisms,...

onlinelibrary.wiley.com
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Pleased to share our review in Water Environment Research on bacteriophage-based technologies for wastewater treatment and anaerobic digestion. The field shows strong potential, but translation to full-scale systems still requires careful validation. Supported by the @NCBR_pl
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nature
@NatureMar 17
Nature research paper: Capturing dynamic phage–pathogen coevolution by clinical surveillance go.nature.com/4saG9iC

Capturing dynamic phage–pathogen coevolution by clinical surveillance

Nature - The acquisition of a parasitic anti-phage mobile genetic element, PLE11, showing potent anti-phage activity against cocirculating ICP1, and the subsequent evolution of ICP1 to escape this...

nature.com
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AllThingsPhages retweeted
Vivek Mutalik@vivek_mutalikMar 15
New paper 🔔 Collaboration w Matt Sullivan Lab, Marissa Gittrich Klebsiella phage biology has focused almost entirely on capsulated strains, but capsule loss is the #1 resistance mechanism under phage predation. We used a naturally acapsular host to reveal the receptor landscape
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AllThingsPhages retweeted
Milan Gerovac@Milan_Gerovac31 Oct 2025
Use antisense oligomers (ASOs) to silence phage genes and discover new biology. @JoergLab, @Helmholtz_HIRI @Helmholtz_HZI @Uni_WUE in print: nature.com/articles/s41586-0… highlighted: nature.com/articles/s41579-0… research briefing: nature.com/articles/d41586-0…
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AllThingsPhages retweeted
Seth Shipman@seth_shipman23 Oct 2025
Been working on a really strange retron bacterial immune system, here's the preprint: biorxiv.org/content/10.1101/… Type VI retrons are unlike any other. Phage infection triggers reverse transcription of a DNA fragment that activates translation of a toxin to kill the infected cell.
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AllThingsPhages retweeted
Bruno Gonzalez Zorn
@_bgzorn_6 Oct 2025
Congrats @jaegc & @AlvSanMillan for this new Project 🫶🏻 ! Discovering activities of anti-microbial resistance genes beyond resistance (Beyond-AMR) fbbva.es/equipo/discovering-… @unicomplutense @CSIC @CNB_CSIC @SEMicrobiologia
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‼️ Already available at @NatureComms the last article of our PhD student @ConchaEloko 😊💪🏼 congrats to all the authors especially Robby and @pilardomingoc! @Rafa_Sanjuan_ Do not miss it ⏩ nature.com/articles/s41467-0…
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AllThingsPhages retweeted
Wendy Figueroa@wfigueroac326 Sep 2025
Thrilled to share our latest paper now out in @ScienceMagazine 🎉🤩 We investigated a century of plasmid evolution 🧬 and uncovered how they have adapted to the antibiotic era 💊 science.org/doi/10.1126/scie…

Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance

Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialization of antibiotics influenced their evolution is limited by a paucity of data...

science.org
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AllThingsPhages retweeted
Samuel King
@samuelhking17 Sep 2025
Many of the most complex and useful functions in biology emerge at the scale of whole genomes. Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵
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