@AliseMuok

Post-doc at Leiden University in the Briegel lab, specializing in structural biology. Chaotic good. https://xitter.cf/t.co/DnqBseP0ke

 Leiden, Netherlands
Joined March 2020
  • Tweets266
  • Following111
  • Followers234
9Media
Don’t miss the new podcast about squids and vibrios! Matters Microbial #12: Shedding light on symbiosis with Ruth Isenberg - YouTube youtube.com/watch?v=oovPHVFH…

Matters Microbial #12: Shedding light on symbiosis with Ruth Isenberg

Today Dr. Ruth Isenberg, postdoctoral scholar (and former #DocMarti...

youtube.com
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Alise Muok retweeted
Zhulin Lab@zhulinlab21 Sep 2023
CheA histidine kinase, the "brain" of bacterial chemosensory systems, is a five-domain protein, as seen in E. coli and B. subtilis. Well, more often than not, this is not true! biorxiv.org/content/10.1101/…
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My name is Alise Muok and I just published my first fiction book! Six Fantasy/SciFi/Horror tales with illustrations and music included. Curious? You can take a look here: barnesandnoble.com/w/books/1…
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How does a pathogenic bacterium search for food? @BriegelAriane and @AliseMuok studied the Treponema denticola, a bacterium that lives in dental plaque 🦷 Their results could have direct medical implications to treat diseases such as Lyme and syphilis edu.nl/b783g

How a pathogenic bacterium searches for food

Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about...

universiteitleiden.nl
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Having this work published is a symbol of perseverance. From getting married, taking a leave for health, and moving to a different country, this work was there the whole way through! Thank you @BriegelAriane @CKeithCassidy @flory_olsthoorn @ortega_science journals.asm.org/doi/10.1128…

A new class of protein sensor links spirochete pleomorphism, persistence, and chemotaxis | mBio

A new class of bacterial protein sensors monitors intracellular levels of S-adenosylmethionine to modulate cell morphology, chemotaxis, and biofilm formation. Simultaneous regulation of these...

journals.asm.org
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Alise Muok retweeted
Zhulin Lab@zhulinlab9 Aug 2023
Bacterial chemoreceptor signaling complexes control kinase activity by stabilizing the catalytic domain of CheA | PNAS pnas.org/doi/10.1073/pnas.22…
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Een passie voor videogames, beeld en wetenschap: het lijkt bijna onmogelijk samen te brengen. Toch heeft wetenschappelijk animator Vera Williams die droomcombinatie gevonden bij het microscopielab van @NeCEN_2p0 🖥️🎨🔬edu.nl/e3m49
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Such a cool article about microbial hitchhiking from Small Things Considered--and they used my paintings!
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Alise Muok retweeted
Zhulin Lab@zhulinlab4 Feb 2023
A new insight into the chemosensory signaling complex machinery by Keith Cassidy and Oxford and Salt Lake City teams! biorxiv.org/content/10.1101/…

Structure of the Native Chemotaxis Core Signalling Unit from E-gene lysed E. coli cells

Motile bacteria detect ambient chemical gradients and control their locomotion via conserved chemotaxis signaling networks, enabling cells to locate nutrients, potential hosts and other important...

biorxiv.org
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Alise Muok retweeted
Sean Booth@ImDrBooth9 Dec 2022
Suicidal chemotaxis in bacteria! Now officially published! We found that Pseudomonas aeruginosa crawls towards lethal antibiotcs. This was a super cool project to work on and I'm stoked to see it out! Check out the preprint thread for details! nature.com/articles/s41467-0…
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Mutations are NOT random. Check out our discoveries published today in @Nature! nature.com/articles/s41586-0… Feeling super lucky to work with an amazing group of scientists on this unexpected and exciting line of research 🙏

Mutation bias reflects natural selection in Arabidopsis thaliana

Nature - Data on de novo mutations in Arabidopsis thaliana reveal that mutations do not occur randomly; instead, epigenome-associated mutation bias reduces the occurrence of deleterious mutations.

nature.com
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Happy to share my newest preprint on spirochete chemosensing! Did you know that an alternative chemotaxis protein also alters biofilm and persister formation? Well you can read more about it here! biorxiv.org/content/10.1101/…

A new class of protein sensor links spirochete pleomorphism, persistence, and chemotaxis

Pathogenic spirochetes can alter their morphologies and behaviors to infect and survive within their hosts. Previous reports demonstrate that the formation of so-called ‘round bodies’ and biofilms,...

biorxiv.org
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Alise Muok retweeted
Xin😼@EnViruSoil13 Dec 2021
You might already know "fungal highway" for motile soil bacteria ( pubs.acs.org/doi/10.1021/es0… ), but how about phages? Can they also be co-transported (or hitchhike, as suggested by @AliseMuok @BriegelAriane doi.org/10.1016/j.tim.2020.1… ) on the fungal highway? (2/8)
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Intermicrobial Hitchhiking: How Nonmotile Microbes Leverage Communal Motility @TrendsMicrobiol #transport @BriegelAriane @AliseMuok hubs.ly/H0Zln_w0
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Day 3 of #microber2021 “No worries, StreptoMike, I can give you a ride!” - said the Bacillus #Flagella (Motivated by… )
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I am very excited to announce that my first, first-author review has just been published in @royalsociety Open Biology with @BriegelAriane and @ClaessenLAB 🎉 doi.org/10.1098/rsob.210199

Cell wall deficiency as an escape mechanism from phage infection

Abstract. The cell wall plays a central role in protecting bacteria from some environmental stresses, but not against all. In fact, in some cases, an elabo

royalsocietypublishing.org
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I am so excited to finally share "I'm a Neutrino"! Featuring modern physics experiments beautifully illustrated by my mother, Ilze Lemesis. She inspired me to pursue my #STEM dreams growing up, now I aspire to encourage kids to do the same. Cute neutrino story time, here we come!
MIT Kids Press@MITKidsPress24 Aug 2021
Before you finish reading this sentence, trillions of neutrinos will have passed through your body. I'M A NEUTRINO by @EveVavagiakis and Ilze Lemesis uses rhyming text and watercolor art to explain these tiny particles to small readers! Coming spring 2022.
Book cover for I'M A NEUTRINO by Dr. Eve M. Vavagiakis, illustrated by Ilze Lemesis. The cover features the title and colorful neutrino characters against a watercolor background.

ALT Book cover for I'M A NEUTRINO by Dr. Eve M. Vavagiakis, illustrated by Ilze Lemesis. The cover features the title and colorful neutrino characters against a watercolor background.

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Thank you @markowenmartin for the wonderful knitted moss piglet! He's so happy with his E. coli and B. burgdorferi friends
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So deeply thankful for the privilege of having a home lab. Without it, given my spinal injury + no formal degree of any kind, I would not be able to work and pay bills. Big huge shout-out to all who hired my services and continue to support my efforts. My little CRO saved me.
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In high school biology, I was paired up with a boy and told to draw what we thought our baby would look like, and that’s the only genetics lesson I ever had until college. Scientists are rare in rural USA and it can cause a divide. So I helped with this: sciencedirect.com/science/ar…
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