@LabGlover alum | Nuxalk Nation in Canada | she/her | https://xitter.cf/t.co/Z3IgaIjCgv
Cambridge, England
Joined February 2016
- Tweets323
- Following262
- Followers328
- Likes2.2K
Alexis L Sperling retweeted
🚨 We’re hiring! Oxford Biology is recruiting 3 new Associate Professors in:
🌱 Plant Sciences
🦉 Animal Behaviour
🔬 Molecular Cell Biology
Join us as we move into our new building with world-class research & teaching facilities.
Vacancies 👉 bit.ly/488CNW3
Alexis L Sperling retweeted
Expansion of chromosome F heterochromatin in parthenogenetic Drosophila mercatorum biorxiv.org/content/10.1101/… #biorxiv_evobio
Alexis L Sperling retweeted
Excited to share our new study revealing the intricate dynamics of pregnancy & postpartum physiology! We analyzed 40M lab tests from 300K pregnancies and 160K women (cross-sectional),
we mapped week-by-week changes starting from preconception to months-long postpartum recovery.
Alexis L Sperling retweeted
1/9 Glad to share the latest work from @VasadL. A collaborative effort to study the role of the electron transport chain in microglia during development.
nature.com/articles/s42255-0…
rdcu.be/dONoN
@NatMetabolism @ibis_sevilla @unisevilla @CSIC #Microglia #Mitochondria
Alexis L Sperling retweeted
New paper!
Our stick insects have weird chromosome segregation.
The major centromere protein, CenH3, binds to the autosomes in a monocentric pattern, but in a holocentric pattern on the X.
doi.org/10.1101/2024.06.30.6…
Alexis L Sperling retweeted
New paper!
Dosage compensation in male reproductive tissues is present only in the early nymphal stages. This is likely due to the establishment of meiotic sex chromosome inactivation during development.
doi.org/10.1101/2024.07.01.6…
Alexis L Sperling retweeted
Excited to share my first author postdoc paper in Developmental Cell cell.com/developmental-cell/… – at Agdal, Royaume du Maroc
We have our very detailed protocol out that walks through the process of going from an intact fly to an annotated genome assembly.
@DK_Fabian, @erikgarrison, and @LabGlover
Online now: Protocol for preparing Drosophila genomic DNA to create chromosome-level de novo genome assemblies dlvr.it/T5SXFY #protocol #starprotocols #cellpress
Alexis L Sperling retweeted
❗️Call for Group Leaders❗️
The @IJMonod, a leading center for fundamental interdisciplinary research in biology, is seeking to appoint at least two new group leaders.
➡️ijm.fr/?lang=en
Apply before February 16th 2024
Application form➡️urlz.fr/ordV
Alexis L Sperling retweeted
There can’t be a better time to present our recent review/perspective on Gastruloids — a minimalistic model to study complex developmental metabolism | Emerging Topics in Life Sciences | Portland Press portlandpress.com/emergtopli… – at Cambridge, England
Alexis L Sperling retweeted
!!!New paper alert with @AlexisLSperling !!!
@PlantMethods
Very nice new in situ protocol for plant-parasitic nematodes - un-ambiguous localisation of multiple transcripts within the same parasite.
plantmethods.biomedcentral.c…
I have a new parthenogenesis paper with @LabGlover!
We found that aneuploidy arises during development in natural Drosophila parthenogens and our genetically induced parthenogens
@HeredityJournal
doi.org/10.1038/s41437-023-0…
Interested in figuring out if an animal is secretly capable of facultative parthenogenesis?
@LabGlover and I made our detailed method available
It works in Drosophila and is worth a try in other animals!
New in: Protocol for screening facultative parthenogenesis in Drosophila #protocol #starprotocols #cellpress dlvr.it/Swh0j5
Alexis L Sperling retweeted
For an excellent start to the week, why not delve into this excellent new preprint by @AlexisLSperling @Seb_EvdA at @CropSciCentre ? 🪱
'Whole mount multiplexed visualization of DNA, mRNA, and protein in plant-parasitic nematodes'
biorxiv.org/content/10.1101/…
Alexis L Sperling retweeted
Wrap your eyeballs around this!
New in situ protocol by @AlexisLSperling
Multiple mRNA, in the same animal, sub-cellular resolution 🥲. Here is DG + SvG effector at the same time.
Preprint:
biorxiv.org/content/10.1101/…
@plantsci @CropSciCentre
There is a great primer by Jonathon Thomalla and @WolfnerLab for my, @DK_Fabian, @erikgarrison, and @LabGlover's work on #Drosophila #parthenogenesis (doi.org/10.1016/j.cub.2023.0…) out in the last issue of @CurrentBiology!
doi.org/10.1016/j.cub.2023.0…
Alexis L Sperling retweeted
Scientists alter the genomes of female fruit flies, allowing them to reproduce without any contribution from a male go.nature.com/458kBr2
Alexis L Sperling retweeted
📢#JobAlert Research Assistant position in my lab:
🪰🧬🧪🔬#Drosophila #genetics #devbio #imaging
In beautiful central Cambridge @GeneticsCam @Cambridge_Uni. Funded by @wellcometrust.
More details and to apply: jobs.cam.ac.uk/job/42219/
Deadline 27 August, please RT!
ALT Confocal microscopy image of the posterior of a blastoderm stage Drosophila embryo. DAPI staining in greyscale, wg transcript in green, cad intronic transcript in yellow, opa transcript in magenta, Opa protein in cyan.
Alexis L Sperling retweeted
Congratulations to first author, @AlexisLSperling, on their recently published paper.
For the first time, scientists have managed to induce virgin birth in fruit flies with the ability to pass this on through the generations 🪰
🔗 shar.es/afMW9e
I am excited to share the final version of our work on the genetic basis of virgin birth (parthenogenesis) in fruit flies! It was a joy working with @DK_Fabian @erikgarrison @LabGlover on this understudied phenomenon.
cell.com/current-biology/ful…
