Building bottom-up synthetic cells @UOW. Husband / Dad. 🦘back in Aus. All views my own.
Wollongong, Australia
Joined November 2019
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Alex Mason retweeted
The Collection of Bespoke #Laboratory #Equipment (#COBLE): #3Dprint your own #lab equipment:
printables.com/de/model/4575…
#DIYbio #3Dprinted #3Dprinting #instruments #OpenSource #OpenHardware
Good news our work developing DIB-BOT is now available on @biorxivpreprint!
If you're interested in...
-artificial cells
-water/oil droplets
-3D printing
-open-source tech
-automating tedious tasks
... you should read the paper, and this thread 🧵
biorxiv.org/content/10.1101/…
In the end, it was actually pretty straightforward. Strap a nanoinjector to a 3D printer, do some rudimentary electronics, and learn gcode (the language that all 3D printers use to navigate x/y/z).
And it works really well! Particularly for making DIBs.
Alex Mason retweeted
Scientists, ethic ists, philosophers, writers, filmmakers, journalists: Join us in Rome for a discussion about what it really means to build life from scratch! Please share!
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Alex Mason retweeted
A new approach to visualize 🧬 #DNAorigami within living cells by @leochou0814 lab! 🧫🔬✨It was a great pleasure to write this #Newsandviews for @NatureNano ! Free access using this link! 👇🏿👇🏽👇🏿👇🏻
nature.com/articles/s41565-0…
Alex Mason retweeted
Can coacervates help form life’s building blocks?
In our new work in @NatureComms, Jiahua & @DrManzarsial show that ferricyanide-rich coacervate protocells are versatile oxidizing hubs that can enhance peptide bond formation and assembly of fibers.
nature.com/articles/s41467-0…
More awesome open science from @V_Saggiomo
I will definitely be using this to sort droplets by size!
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Alex Mason retweeted
New article on complex coacervate artificial cells now online. Thanks very much to Bruno (@ciqususc) for the collab, and of course @vanhest_lab! We looked at the effect of cationic polymer structure on coacervation and enzyme part./activity @MacroJrnls_ACS pubs.acs.org/doi/10.1021/acs…
Alex Mason retweeted
Out this week in @angew_chem: we introduce for the first time ELIDIS, an Enzyme-Linked DNA Displacement assay for the electrochemical detection of antibodies! A short thread below on why I think this is a very important step for our group. 1/7
Enzyme-Linked DNA Displacement (ELIDIS) Assay for Ultrasensitive Electrochemical Detection of Antibodies (Francesco Ricci and co-workers) @RicciLab @Simona_Ranallo @anadfdez onlinelibrary.wiley.com/doi/…
Alex Mason retweeted
New content online: Interlinking spatial dimensions and kinetic processes in dissipative materials to create synthetic systems with lifelike functionality dlvr.it/Szn7cz
Room for improvement - 3+ droplets. Working on this, but can already show potential for n "colour" droplet experiments
So, want to build one? well, here is the Github:
github.com/AFMason/DIB-BOT
It's incomplete but I will be updating it as I build another DIB-BOT here at @MolHorizons @uowresearch. And a preprint will be uploaded before xmas...
As @V_Saggiomo says, the Ender3 is the cheapest cartesian robot you can buy!
And Gcode (the code that tells 3D printers how to move) is surprisingly easy to learn.
Give it a go! I, for one, welcome our new robot overlords.