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A few thoughts on AI, latent space, the geometry of knowledge, and why the humanities may become more—not less—important in the age of agentic AI.
Link: open.substack.com/pub/albert…
Alberto Mencarelli retweeted
Should Europe leave frontier AI to the Americans and the Chinese?
The idea has gained ground in Europe. It is a fundamental mistake.
Build or surrender: for now, the choice is still ours.
Full article below.
Alberto Mencarelli retweeted
Meet Mistral Large 4, aka Le Chonk.
• 1T parameters, natively multimodal. 49B active.
It is the best open weights model from US or Europe on aggregated benchmarks.
• State-of-the-art on critical workloads, including cyber defense, manufacturing and finance and it surpasses closed frontier models on visual grounding.
• Forged in Europe end-to-end and is deployable from Europe via our own Mistral Cloud infrastructure.
• Available to all via API today. Working with cybersecurity partners privately.
Open weights release end of October.
🤖 Made with AI
Introducing Griffin, the first model to pass the video Turing test.
48% of people who talked to it live thought it was a real human. Previous systems have had a pass rate <3%. It is #1 on NVIDIA's benchmark for full-duplex AI video.
It’s the first Human Interaction Model (HIM).
Readers added context they thought people might want to know
The 48% figure and "video Turing test" claim are from Tavus's own study of 54 one-minute calls, not independently verified or using a standard protocol. Griffin-Lite leads NVIDIA's VideoFDB benchmark on their public leaderboard.
cellcog.ai/blog/tavus-gri…
research.nvidia.com/labs/amri/proj…
tech-ish.com/2026/10/02/tav…
Your dot can do simple things like book a table—or take on your most ambitious work with the initiative of a high-agency engineer or chief of staff.
It has its own computer and works across 4,000+ apps through ChatGPT, using the plugins you connect.
It learns what you need and gets to work before you ask, quietly in the background, 24/7.
openai.com/index/introducing…
We heard you loud and clear. ChatGPT Voice can now:
- Use plugins like your email, calendar, and Slack.
- Be powered by GPT-6 Astra, Sol, and Luna.
- Be used in ChatGPT Work on web and mobile, so you can create docs, decks, sites, and spreadsheets or tackle complex tasks in the browser, just by talking.
Rolling out globally today in the latest version of the app.
Alberto Mencarelli retweeted
Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR.
We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use.
Read more: anthropic.com/news/claude-di…
Alberto Mencarelli retweeted
Today we proposed the EU KIDS Act.
No social media under the age of 13. No personal accounts under the age of 15. That’s our recommendation.
As European Commission President, @vonderleyen said: “The question is not whether kids should have access to social media. The question is whether social media platforms should have access to our children.”
Words matter: Canada as the EU’s first associate member—an alliance, as Carney said today, that other countries may join in the future. This goes beyond a single association agreement; it lays the groundwork for something else, to run parallel to the ordinary enlargement process.
The EU AI Act was remarkably prescient in anticipating the terms of today’s frontier-AI safety debate. For signatories such as OpenAI and Anthropic, “pacing the frontier” now has a regulatory grounding in Art. 55 and, even more explicitly, in Measure 4.2 of the GPAI Code.
Alberto Mencarelli retweeted
I agree with Dario that we need to pace the frontier. This has been a primary topic of discussions we've had at OpenAI in recent weeks.
Committing to having independent evaluators with employee-like access is a great idea, and we will do the same. We'll have more to share soon.
We Must Pace the Frontier: I’ve written a new essay on why the AI industry should slow down, with a three-part plan for doing so.
Anthropic is unilaterally committing to the first of these steps. We’ll provide third-party evaluators with permanent, employee-level access to our systems, so that they can verify adherence to our safety measures, report on incidents, and assess models’ alignment during training.
You can read the full post here: darioamodei.com/post/we-must…
Alberto Mencarelli retweeted
We Must Pace the Frontier: I’ve written a new essay on why the AI industry should slow down, with a three-part plan for doing so.
Anthropic is unilaterally committing to the first of these steps. We’ll provide third-party evaluators with permanent, employee-level access to our systems, so that they can verify adherence to our safety measures, report on incidents, and assess models’ alignment during training.
You can read the full post here: darioamodei.com/post/we-must…
Alberto Mencarelli retweeted
We're publishing our most detailed threat intelligence report to date.
It covers how people tried to misuse Claude—for cyberattacks, influence operations, surveillance, biology, and building weapons—and how we found and stopped them.
We disrupted every operation in the report, and used the lessons from them to strengthen our safeguards. Where appropriate, we also shared what we found with authorities and other AI companies.
These cases are not typical: we’re highlighting some of the most sophisticated misuse we’ve seen. But they’re especially important to discuss, because they show us where AI misuse is headed, where our safeguards work, and where they need to improve.
We’re publishing this report so others can spot the same activity on their own platforms, and so we can give the public a clearer view of how emerging threats develop.
Read the report: anthropic.com/threat-intelli…
The problem is that the explosion of the AI revolution coincides with a time when global relations are falling apart. But an international regulation (an AI Treaty?) is urgently needed.
A must-read
I wrote about the state of AI, why I’m concerned about the next few years, and the choices we need to make to keep the future in humanity’s hands.
An Alien Mind: openai.com/index/an-alien-mi…
As we prepare to release Astra, we’re focused on making increasingly capable AI safe and broadly accessible.
Astra represents a significant advance in cybersecurity capability, reaching the Critical threshold under our Preparedness Framework.
We're previewing how we evaluated the model, how its safeguards have advanced alongside its capabilities, and what we'll continue to learn and improve.
openai.com/index/path-to-ast…
Alberto Mencarelli retweeted
For those looking for my views on Europe: I wrote with @bengtmit and @CompetitionProf a manifesto on where Europe went wrong and what we need to do: Europe needs to center its aim squarely and uniquely on creating prosperity for its citizens constitutionofinnovation.eu/
Alberto Mencarelli retweeted
Moderna and @Merck today announced positive topline results from the Phase 3 INTerpath-001 trial evaluating adjuvant treatment with intismeran autogene, a novel investigational mRNA-based individualized neoantigen therapy jointly developed by Merck and Moderna, in combination with KEYTRUDA® (pembrolizumab), Merck's anti-PD-1 therapy, in patients with completely resected Stage IIB-IV melanoma.
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