
ALT Figure 1 – Differential protein changes between biologically determined AD compared to non-AD (cohort 1) in plasma (A), serum (B) and CSF (C). In the volcano plots the red coloured dots indicate proteins significantly different between groups after FDR correction for multiple comparisons, whilst blue coloured dots indicate proteins nominally significant. The horizontal dashed line indicates the unadjusted P value threshold of 0.05.

ALT Figure 2 – Differential plasma protein changes between MCI+ and MCI- (A), LB+ vs AD (B) and GRN+ and GRN- (C). In the volcano plots the red coloured dots indicate proteins significantly different between groups after FDR correction for multiple comparisons, whilst blue coloured dots indicate proteins nominally significant. The horizontal dashed line indicates the unadjusted P value threshold of 0.05.
















