@AThomasLab

We are a synthetic methods group at Texas A&M University. We use rapid injection NMR (RI-NMR) to study mechanisms and reactivity. Student ran account.

 College Station, TX
aathomasgroup.com
Joined September 2021
  • Tweets316
  • Following234
  • Followers851
81Media
Check out our recently developed Rapid-Injection Paper out now in Organic Letters! A Modular Rapid-Injection NMR for Structure Elucidation and Kinetic Analysis pubs.acs.org/orlef7/article/…

A Modular Rapid-Injection NMR for Structure Elucidation and Kinetic Analysis

Abstract. Rapid-injection nuclear magnetic resonance (RI-NMR) spectroscopy transforms a standard NMR tube into a reaction vessel within the NMR spectromete

pubs.acs.org
3
12
1,265
The Thomas group has graduated PhD #5! Congratulations to Dr. Seokmin Kang on a successful PhD defense!
1
21
691
The Thomas group is very proud to call Griffin a member of our group!
Rusty Surette
@RustySuretteTVSep 30
💬 “Hi Rusty, I don't know if you've heard about this, but earlier this month at the 1720 apartments in College Station, an Amazon driver passed out while delivering a package due to the heat. Griffin Batson, stepped in and saved the day. He not only called 911, but also gave the man water and cold towels. On top of ALL of that, he safely delivered the package for the Amazon man. Truly a local boy turned hero. Best, Kennedy Barnes” #SendItToRusty
6
264
The Thomas group has graduated PhD #4! Congratulations to Dr. Han-Hsiang Hsu on a successful PhD defense!!
2
2
19
521
The Thomas Group 🦖 retweeted
Boron-Chem-Research@Boron_ChemistryApr 15
Direct Access to Carbenoids from Alkyl and α-Acyloxy Halides for Boron Homologations ( @ChemRxiv ): chemrxiv.org/doi/full/10.264… ( @AThomasLab ).
6
59
2,889
Check out our newest paper out now in ACS Catalysis! Mechanistically Driven Development of Kumada Catalyst-Transfer Polymerizations: A Rapid Injection NMR Study | ACS Catalysis pubs.acs.org/doi/10.1021/acs…

Mechanistically Driven Development of Kumada Catalyst-Transfer Polymerizations: A Rapid Injection...

Abstract. Transmetalation is a pivotal step in the Kumada–Tamao–Corriu cross-coupling reaction, yet its mechanistic details have remained relatively unexpl

pubs.acs.org
9
62
3,398
Check out our newest paper in Nature Communications where we developed a LED Rapid Injection NMR! nature.com/articles/s41467-0…

Design of a combined LED and rapid-injection NMR system for structure elucidations and kinetic...

Nature Communications - NMR spectroscopy is a powerful tool for studying chemical reactions, but short-lived intermediates are hard to capture. The authors present a system combining LED and...

nature.com
5
20
1,732
The Thomas Group 🦖 retweeted
Lupita S. Ramirez@ls_aguirre30 Jun 2025
Have you ever run a rxn using a gas reagent? Did you wish you could monitor it in real time? Now you can😎! Check out our new GRI-NMR system to monitor rxns using a continuous flow of a gas reagent at 1atm. ⁦⁩@AThomasLab⁩ ⁦@jeanettephos⁩ ⁦⁦⁦@ChemMethods⁩
1
4
23
1,124
New Paper Alert! Congratulations to @ls_aguirre, @jeanettephos, and Raquel! Design of a Gas Rapid Injection Nuclear Magnetic Resonance System for Structure Elucidations and Kinetic Analyses - Aguirre - Chemistry–Methods - Wiley Online Library chemistry-europe.onlinelibra…

Design of a Gas Rapid Injection Nuclear Magnetic Resonance System for Structure Elucidations and...

A gas rapid injection nuclear magnetic resonance (GRI-NMR) device was designed and constructed for the precise delivery of gases at atmospheric pressures for real-time data acquisition. The GRI-NMR...

chemistry-europe.onlinelibrary.wiley.com
6
25
1,938
The Thomas group has graduated PhD #3! Congratulations to Dr. Lupita Aguirre @ls_aguirre on a successful PhD defense! She will be heading west to the University of California-Los Angeles. Where she will join Prof. Osvaldo Gutierrez's lab as a Post Doc!
8
4
1
69
5,804
The Thomas group has graduated PhD #2! Congratulations to Dr. Danniel Arriaga on an amazing defense. He will be taking his talents to the University of Wisconsin-Madison, where he will be working with Prof. Julian Cooper as a Post-Doc!
2
37
3,475
Development of a Highly Selective Synthesis of 4-Substituted Tetrahydroquinolines: Substrate Scope and Mechanistic Study (Andy A. Thomas @AThomasLab and co-workers) #openaccess 🔓 onlinelibrary.wiley.com/doi/…

Development of a Highly Selective Synthesis of 4‐Substituted Tetrahydroquinolines: Substrate Scope...

A general and selective deprotonation capture sequence of tetrahydroquinolines with alkyl halides and aromatic halides at the 4-position using organolithiums and phosphoramide ligands is described....

chemistry-europe.onlinelibrary.wiley.com
3
16
1,710
The Thomas Group 🦖 retweeted
J. Am. Chem. Soc.@J_A_C_S1 Apr 2025
Future JACS authors from Texas A&M (D. Chattapadhyay, P. Castro Castro, L. Aguirre, S. Malavika, J. Pina, J. Nicholson) @TAMUChemistry @TAMU
1
12
1
76
26,209
The Thomas group has graduated PhD #1! Congratulations to Dr. Jeanette Piña @jeanettephos on an amazing defense yesterday. She will be heading to Savannah River National Lab!
3
4
2
67
5,155
New Paper Alert! Congrats to @jeanettephos, @ls_aguirre, Levi, Hi, and @CrockettChem! Development of a Highly Selective Synthesis of 4–Substituted Tetrahydroquinolines: Substrate Scope and Mechanistic Study - A European Journal - Wiley Online Library chemistry-europe.onlinelibra…

Development of a Highly Selective Synthesis of 4‐Substituted Tetrahydroquinolines: Substrate Scope...

A general and selective deprotonation capture sequence of tetrahydroquinolines with alkyl halides and aromatic halides at the 4-position using organolithiums and phosphoramide ligands is described....

chemistry-europe.onlinelibrary.wiley.com
1
5
21
1,833
New Year New Paper! Congrats to @HanHsiang_Hsu, Seokmin, Cheng-Chun, and @MdRajaSk1994! Functionalization of Pyridines at the C4 Position via Metalation and Capture - Thomas - Angewandte Chemie International Edition - Wiley Online Library onlinelibrary.wiley.com/doi/…

Functionalization of Pyridines at the C4 Position via Metalation and Capture

n-Butylsodium can be used to selectively deprotonate pyridine at the C4 position, in sharp contrast to organolithium reagents which lead to nucleophilic addition at the C2 position. A wide range of...

onlinelibrary.wiley.com
1
4
49
4,133
The Thomas Group 🦖 retweeted
Chemistry at Thieme
@thiemechemistry3 Jan 2025
Interested in organolithium chemistry? Andy Thomas (@AThomasLab), @CrockettChem, @ls_aguirre, Shu-Kai Chen and Raja SK have compiled a #ScienceOfSynthesis review on practical advances in the application of Li in organic synthesis (Ed: Renzo Luisi @Luisi_Lab) @TAMUChemistry 🧐
8
1
46
4,673
We are excited to share that our book chapter titled "Advances in Lithium Metal Sources: Synthesis and Applications." has been published in Science of Synthesis Knowledge Updates! Congratulations to @CrockettChem, @ls_aguirre, Shu-Kai and Raja! DOI: 10.1055/sos-SD-108-00398
1
2
13
1,614
Our newest paper is available on ChemRxiv! Congrats to @jeanettephos, @ls_aguirre, Levi, Hai, and @CrockettChem! Development of a Highly Selective Synthesis of 4-Substituted Tetrahydroquinolines: Substrate Scope and Mechanistic Study | ChemRxiv - go.shr.lc/3CoHwoG

Development of a Highly Selective Synthesis of 4-Substituted Tetrahydroquinolines: Substrate Scope...

Herein, we describe a general and selective deprotonation functionalization reaction of tetrahydroquinolines at the 4–position using organolithiums and phosphoramide ligands. In addition to the...

chemrxiv.org
1
8
792
The Thomas Group 🦖 retweeted
Organic Syntheses@OrgSynth25 Oct 2024
Preparation of Highly Reactive Lithium Metal Dendrites and the Synthesis of (Trimethylsilyl)methyllithium Raquel M. Gonzalez, Han-Hsiang Hsu, and Andy A. Thomas @AThomasLab orgsyn.org/demo.aspx?prep=v1…
5
30
3,682
Load more