Giel van Dooren and his team of Toxo Avengers. Doing Toxo Research since 2012!
Canberra, Australia
Joined February 2020
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Come join our fabulous department to undertake a PhD!
Want to undertake a cutting-edge PhD in molecular sciences? Are you a high-achieving student (Australian or New Zealand citizen or PR)? Contact one of our award-winning research Group Leaders to express your interest: rb.gy/uhtyfc / Info: rb.gy/g9jjgf
A new paper from our group investigating the essential role of an iron-sulfur (Fe-S) protein in the cytochrome c oxidase complex (Complex IV) of the Toxoplasma mitochondrial electron transport chain! 1/9
journals.plos.org/plospathog…
What might the role of the Fe-S clusters on Complex IV be? We don’t know for certain. The lability of ApiCox13 when lacking its Fe-S clusters could mean that ApiCox13 regulates Complex IV and ETC function in response to iron availability or levels of reactive oxygen species. 8/9
Check out this Research Officer position in our department with Alex Maier's group!
Exciting opportunity for a Research Officer to join the team at BSB! Contribute to the development of a novel drug delivery system to target parasitic infections and related diseases affecting millions globally. bit.ly/3Ttgy3V#researchjobs #parasiticinfections #drugdelivery
A really cool new manuscript from Adele Lehane’s lab @ANU_RSB_BSB , demonstrating that a single amino acid change in the sodium pump of Plasmodium parasites confers >1000-fold resistance to a leading new anti-malarial drug called cipargamin. 1/8
nature.com/articles/s41467-0…
As cipargamin and other PfATP4 inhibitors make it to the field, it will be important to monitor for the G358S mutation as a marker for emerging resistance. 7/8
Great work by Deyun, Victor and James, and many collaborators including @CorryLab , @fidocklab , @PhotiniSinnis17 and Marcus Lee. Glad we could contribute on the Toxo side of things! 8/8