@AC_Williamson

Postdoc @QMUL leveraging human genomics to understand complex diseases 👩🏻‍🔬👩🏻‍💻| Previously PhD student @IMS_MRL @MRC_Epid | Views my own

 London, United Kingdom
Joined April 2017
  • Tweets88
  • Following430
  • Followers177
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Alice Williamson retweeted
Moneeza K Siddiqui@KsMoneeza26 Nov 2024
@GenesHealth, Sam Hodgson, @Sarah_Finer & I are very pleased to share the 1st study using partitioned polygenic scores to understand age of T2D onset, GDM, lean T2D & 💊 response. All this in a south Asian cohort – typically under-represented in 🧬 research @QMUL_WIPH @QMUL_CEG
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Great postdoc opportunity in @DPhaz lab @IMS_MRL working on an exciting collaborative project (jobs.cam.ac.uk/job/47744/ )⬇️
Daniel Fazakerley@DPhaz6 Aug 2024
We are looking for a Postdoc to investigate novel genes that regulate insulin-stimulated glucose transport (tinyurl.com/ycarykzh). MRC-funded collaboration with O'Rahilly (@StephenORahilly) @IMS_MRL & Langenberg groups (QMUL). Please RT. Link: tinyurl.com/57ea9p3f
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Alice Williamson retweeted
Daniel Fazakerley@DPhaz6 Aug 2024
We are looking for a Postdoc to investigate novel genes that regulate insulin-stimulated glucose transport (tinyurl.com/ycarykzh). MRC-funded collaboration with O'Rahilly (@StephenORahilly) @IMS_MRL & Langenberg groups (QMUL). Please RT. Link: tinyurl.com/57ea9p3f
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Pleased to see our perspective piece out in @ScienceMagazine Published along side the huge multi-ancestry GWAS effort in MVP from Verma et al (science.org/doi/10.1126/scie…), @SFatumo and I discuss the importance of increased diversity in genomic studies.
Segun Fatumo@SFatumo19 Jul 2024
Excited to share our new perspective @ScienceMagazine We highlight the need for broader representation in genomic research to ensure global health equity The new MVP cohort shows progress with 29% non-EUR ancestry, but more efforts are needed in LMICs science.org/doi/10.1126/scie…
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Alice Williamson retweeted
Moneeza K Siddiqui@KsMoneeza4 Mar 2024
The A-team (plus me!) are in #chiangmai and excited to deliver a 1 week course on genetic epidemiology at the #CMU Center of multidisciplinary technology for advanced medicine. Thailand ❤️ @MargheBigossi @AC_Williamson @Ladyroho @QMUL_CEG @QMUL_WIPH
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Alice Williamson retweeted
omicscience@omicscience1 Mar 2024
#Fasting shaped human evolution and is practiced by billions of people for #health and #religious reasons, but what happens to our body beyond shifting energy sources? What happens to our bodies in *7 days* w/o any food? nature.com/articles/s42255-0…
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Alice Williamson retweeted
omicscience@omicscience24 Jul 2023
🚨preprint alert🚨 We demonstrate how #Proteomics can improve preventive screening across >50 diseases in @uk_biobank with ~50k participants Massive improvements for severe diseases like multiple myeloma or non-Hodgkin lymphoma with ≤5(!) proteins medrxiv.org/content/10.1101/…

Proteomic prediction of common and rare diseases

Background For many diseases there are delays in diagnosis due to a lack of objective biomarkers for disease onset. Whether measuring thousands of proteins offers predictive information across a wide...

medrxiv.org
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#NatMetabPicks | In @NatureGenet from @AC_Williamson et al. (@QMUL): #GWAS of two oral GTT-derived measures of postprandial #insulin resistance discover 10 new loci. Functional characterization identifies 9 candidate genes implicated in regulating GLUT4. nature.com/articles/s41588-0…

Genome-wide association study and functional characterization identifies candidate genes for...

Nature Genetics - Genome-wide association analyses of two oral glucose tolerance test-derived measures of postprandial insulin resistance discover ten new loci. Functional characterization...

nature.com
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Dynamic measures of insulin action identify genetic determinants of dysglycemia | Nature Genetics nature.com/articles/s41588-0…
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How do we control our blood sugar after a meal or sugary drink? A new study has found genetic clues to help explain how this process can break down and increase our risk of developing type 2 diabetes. @IMS_MRL @MRC_Epid bit.ly/43MSvRu
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Excited to see our work on the genetic architecture of post-challenge insulin resistance out today in Nature Genetics: nature.com/articles/s41588-0… 1/6
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We couple this genetic analysis with functional follow-up of genes at the loci we identify in cellular assays and identify new genes implicated in insulin-stimulated glucose uptake and GLUT4 trafficking 5/6
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Read more here: nature.com/articles/s41588-0… 6/6
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Alice Williamson retweeted
omicscience@omicscience24 Feb 2023
Our work where we integrated #Genetics with #Proteomics to identify links to metabolic and a diverse range of diseases is now published in @NatMetabolism 👉 rdcu.be/c6fr6
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Alice Williamson retweeted
omicscience@omicscience10 Nov 2022
Many people are on a path to T2D without knowing, as they are being missed by current screening guidelines - isolated impaired glucose tolerance (iIGT). We identified a novel #proteomics test to help identify them. nature.com/articles/s41591-0…
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Alice Williamson retweeted
omicscience@omicscience10 Nov 2022
Exciting news! Our collaborative paper uncovering the extent of links between genetics, the metabolome and health has been published. ~1000 metabolites, ~20,000 people #Genetics #Metabolomics nature.com/articles/s41591-0… @MRC_Epid @CAMBRIDGE_CEU

Rare and common genetic determinants of metabolic individuality and their effects on human health

Nature Medicine - Analyses of the genetic architecture of the human plasma metabolome in two large population-based cohorts identify associations between genetically determined metabolite levels...

nature.com
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Excited to be in LA at #ASHG22 for 5 days filled with the latest in human genetics! Looking forward to sharing our work on the genetic architecture of post-prandial insulin resistance in the poster session on Wednesday afternoon (PB1392) 🧬
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