Aram Chung retweeted
In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles nature.com/articles/s41587-0…
Aram Chung retweeted
Jang et al., Microfluidic Mechanical Reactivation of Senescent Stem Cells, Small (Wiley, 9 September 2026), Konkuk University and Korea University, Seoul; figures cited from the bioRxiv preprint version.
onlinelibrary.wiley.com/doi/…
Aram Chung retweeted
A study from @GDE_UTSW developed a polymer-lipid hybrid nanoparticle platform enabling programmable encapsulation and controlled organ-specific delivery of diverse RNA payloads. Learn more: go.nature.com/4zPsMbD.
Aram Chung retweeted
Microfluidics-mediated spatial control of mRNA lipid nanoparticles primes translation and enhances vaccine potency go.nature.com/4rpmX0I
Our recent work on microfluidic mechanical reactivation/rejuvenation of aged stem cells has been published in Small
Microfluidic Mechanical Reactivation of Senescent Stem Cells
onlinelibrary.wiley.com/doi/…
Aram Chung retweeted
Lipid nanoparticles chart path beyond the liver nature.com/articles/s41587-0…
[🔓read free with login]
Aram Chung retweeted
For readers interested in the potential of in vivo CAR-T cell therapies for cancer and autoimmune diseases, here's a comprehensive review by pioneers in the field
rdcu.be/koc33UDidsza
nature.com/articles/s41573-0…
Aram Chung retweeted
Excited to share that Spatial Hi-C-RNA is now out in @CellCellPress! It brings the 3D genome into spatial multi-omics by co-mapping chromatin architecture and gene expression in the same tissue section. Congrats to the whole team! cell.com/cell/fulltext/S0092…
Aram Chung retweeted
”Genome-wide CRISPR screening identifies cellular factors controlling nonviral genome editing efficiency”
Shivani Saxena, Meha Kabra [..] Krishanu Saha
Nat Commun. 2026-08-13.
doi.org/10.1038/s41467-026-7…
#CRISPR #DDS
Aram Chung retweeted
mRNA technology is one of the platforms being used for n-of-1 therapies. Read about its application in this and a range of other areas such as in vivo CAR-T cell therapies and cancer immunotherapies in this Review nature.com/articles/s41573-0…
rdcu.be/fteeb
Aram Chung retweeted
Multifunctional-engineered NK cells overcome tumor immunosuppression by combining PD-L1 and HLA-E targeting and endogenous IL15 production 🇮🇹
nature.com/articles/s41392-0…
Aram Chung retweeted
Single-cell spatial pharmacobiology identifies conserved stromal barriers to therapeutic antibody delivery in human solid tumors go.nature.com/4atBJML
Aram Chung retweeted
In cancer, activated T cells release abundant extracellular vesicles that transfer DNA to the nucleus of tumor and immune (dendritic) cells, turning tumors from cold to hot. An immunotherapy in the works. @Cancer_Cell
sciencedirect.com/science/ar…
sciencedirect.com/science/ar…
Aram Chung retweeted
CAR-X cell engineering dlvr.it/TSG6WV
Aram Chung retweeted
A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery go.nature.com/4ugPm9D
Aram Chung retweeted
Macrophage senescence is a central driver of chronic inflammation in aging and metabolic liver disease, and a tractable therapeutic target.
Aram Chung retweeted
In the latest issue! Hallmarks of cancer—Then and now, and beyond dlvr.it/TS4Plc
Aram Chung retweeted
A lysosomal barcoding strategy to quantify endosomal escape of nucleic acids in vivo assesses the performance of branched ionizable lipids for potent liver delivery #NBTNV go.nature.com/4s4X7P7
rdcu.be/fdfzQ
Aram Chung retweeted
Steady progress towards engineering immune cells in the body now for refractory myeloma , with major implications for many autoimmune diseases and cancers
nature.com/articles/s41591-0…
nature.com/articles/s41591-0…
Aram Chung retweeted
For readers interested in lipid nanoparticles for oligonucleotide delivery, here's an article covering 60 years of progress in the field
rdcu.be/fb9xD
nature.com/articles/s41573-0…


























