@48HourDiscovery

Entrepreneurs bridging Biology, Chemistry, and Information Technology to overcome the fundamental rate-limiting steps in discovery of new functional molecules

 Edmonton, Alberta
Joined March 2018
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#LiGA liquid glycan array technology to discover glycan protein interactions is published on BioRvx
Ratmir Derda@RatmirDerda25 Mar 2020
DNA encoding of glycans on viral scaffold to use #ngs to study #glycobiology in vitro/in vivo and the role of #multivalency in #glycan interactions with #lectins, #siglecs, #antibodies at biorxiv.org/content/10.1101/… @derda_lab @MatthewMacaule4 @Lowarylab @jcpJim @Ccling @glyconet_nce

Genetically Encoded, Multivalent Liquid Glycan Array (LiGA)

The Central Dogma of Biology does not allow for the study of glycans using DNA sequencing. We report a “Liquid Glycan Array” (LiGA) platform comprising a library of DNA ‘barcoded’ M13 virions that...

biorxiv.org
48Hour Discovery retweeted
Research2Reality@r2rnow28 Nov 2017
{New post} By mixing billions of molecules in a flask, this @UAlberta spin off could make it faster than ever to find new drug candidates ow.ly/zUyE30gS0Zu @RatmirDerda #48hourdiscovery
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Standardization and sharing of biological data is critical to AI and synbio realizing its potential to solve the next big challenge @VectorInst @DonellyCentre #48hourdiscovery @nmagarvey1 #2018CanadaSynBio
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