Being goofy and enjoying life

Seattle, WA
Joined June 2012
⚡️ “Allen Mouse Brain Common Coordinate Framework - Gallery” xitter.cf/i/moments/137156029758…
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After 20+ years at @AllenInstitute, I’m retiring. It’s been a privilege to have work alongside so many wonderful scientists, engineers, technicians, PMs and support staff in the pursuit of understanding the brain and sharing data and knowledge with the world.
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I am proud to have to play a part in this noble mission. Seeing our resources used in the wild and watching the next generation come through the ranks brings me immense joy. Thank you all, cheers and all the best!
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The data involved with this research is freely available to accelerate research and discovery. Browse the SEA-AD Brain Cell Atlas, made possible by a @NIHAging-funded collab with @UWMedicine & @KPWaResearch. 🔗 portal.brain-map.org/explore… #studyBRAIN
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📣NEXT WEEK! Join us @AllenInstitute for a night of storytelling that take you behind the scenes of Allen Institute science with @han_arbach, Ashwin Bhandiwad, Max DePartee, Rachel Hostetler & Rachel A McCue. 🎟️ Livestream & in-person tickets: ow.ly/skvC50Tannm
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Sharing🤯video to get you through Friday! Credit: @E_cross_B @Blender animation of the Allen Mouse Common Coordinate Framework (#CCF). Outer structures "explodes" out to reveal inner brain structures. @AllenInstitute
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We've begun rolling out anatomical annotations to the Allen Brain Cell Atlas! The first data set to support these annotations is the MERFISH Spatial Transcriptomics Dataset of a Single Adult Mouse Brain - registered to CCFv3. 🔗 knowledge.brain-map.org/abca…
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Whole, healthy human brain data is now on the ABC Atlas! Dataset incl. 3 million+ cells sampled from dissections from adult donors. Samples underwent snRNA sequencing and were clustered and categorized by neurotransmitter, region, and more. ABC Atlas: portal.brain-map.org/atlases…
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⭐New data are available on the Allen Brain Cell (ABC) Atlas The ABC Atlas provides a platform for visualizing multimodal single cell data across multiple whole-brain datasets simultaneously. #OpenScienceWeek. Visit: portal.brain-map.org/atlases…
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We are delighted to be working with @awscloud and #BRAINInitiative to create first of its kind cell types knowledge base spanning modalities, species and developmental stages and making these resources available to the research community! @AllenInstitute #studyBRAIN
With @awscloud, the @AllenInstitute is mapping the whole human brain and creating the largest open-source brain cell database in the world. The team is looking to leverage generative AI services like Amazon Bedrock to integrate foundation models into this first-of-its-kind platform to advance treatment for brain disorders. A true example of how #AI and #ML will change lives for the better. aboutamazon.com/news/aws/how…
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Congratulations @HongkuiZeng!
Congrats to our own @HongkuiZeng on being elected to @theNASciences! She was chosen for her contributions to society's understanding of mammalian brain cells and connections, and leading the development of #OpenScience data and tools. alleninstitute.org/news/hong…
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I asked a chat service to write a haiku about spatial transcriptomics ... Genes in space we see, Spatial transcriptomics tech, New insights we glean.
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On this day in 2014, we published the Allen Mouse Brain Connectivity Atlas, the first comprehensive, large-scale data set on how the brain of a mammal is wired. #Allen20 Learn more: reuters.com/article/us-scien… #NeuroTwitter
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Ed Lein kicking off the first #HMBA consortium meeting @AllenInstitute #BICAN #studyBrain
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Inhomogeneity correction required
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TFW you have to parse large unknown xml file just to prove a point
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the only people I’ve seen dismissing this insightful article are ones who don’t seem to understand compression very well the only surprise(?) is that it took a skilled writer and thinker, instead of one of us researchers, to make the case crystal clear newyorker.com/tech/annals-of…
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So glad that our cute little human brain schematic is finding reuse after all this time @AllenInstitute #openscience
‼️New preprint‼️ medrxiv.org/content/10.1101/… Disease progression modeling of: * 3⃣ TDP-43 proteinopathies (ALS, FTLD-TDP, LATE-NC) * Postmortem TDP-43 data from 22 🧠 regions * N = 571 donors We set out to create order from the progression patterns of these 3 proteinopathies? 1/13
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