Proteins biochemistry and structural biology. Head of the cryo-EM unit @bengurionu
Israel
Joined May 2016
- Tweets702
- Following492
- Followers528
- Likes2.6K
Ran_Zalk_BGU_Cryo_EM retweeted
We proudly present our latest paper: “Ligand-induced activation of RyR1 in native membranes” RyR1 is a key protein in the excitation-contraction coupling of skeletal muscle and the largest membrane protein in humans. Paper here, thread below:
nature.com/articles/s41467-0…
What a privilege to be mentioned again alongside these authors.
nature.com/articles/s41467-0…
Ran_Zalk_BGU_Cryo_EM retweeted
Happy to share the results of our study of structural and functional regulation of GluA2 AMPA receptor by inhibitory auxiliary subunits GSG1L and TARP gamma5 and by epilepsy-associated disease mutations. @shantigangwar @MariaKarela3 @MKCMU
nature.com/articles/s41467-0…
Nice
!
Gating Mechanism of the Human Connexin 45 Gap Junction Channel biorxiv.org/content/10.64898…
Ran_Zalk_BGU_Cryo_EM retweeted
Officially out in Nature Communications: Structures of the most abundant AMPA receptor di-heteromer in the brain GluA1/A2 in the closed, open, and desensitized states! @shantigangwar @MariaKarela3 @LauraYen42 @MKCMU
nature.com/articles/s41467-0…
The assembly rules guiding hetero-oligomeric bacterioferritin organization and their evolutionary signature | PNAS pnas.org/doi/10.1073/pnas.25…
Ran_Zalk_BGU_Cryo_EM retweeted
Recently honored to host the UK Ambassador to Israel, Simon Walters (@simonwaltersuk), at our lab at Ben-Gurion University ! 🇮🇱🇬🇧 We had an insightful discussion about the challenges of Alzheimer’s disease. Thank you for supporting scientific cooperation! @bengurionu @ukinisrael
This looks very useful!
Flexible fitting of AlphaFold2-predicted models to cryo-EM density maps using elastic network models: a methodical affirmation academic.oup.com/bioinformat…
Ran_Zalk_BGU_Cryo_EM retweeted
A new paradigm for outer membrane protein biogenesis in the Bacteroidota
BAMの新しい複合体構造
nature.com/articles/s41586-0…
Ran_Zalk_BGU_Cryo_EM retweeted
🚨 Happy to share our new preprint in which we explore different layers of the phage-bacteria arms race.
The highlight: phage homing endonucleases attenuate bacterial defenses 🤯
A 🧵... (1/7)
#bacteriology #antiphage #T6SS
@TelAvivUni @TAUMedFaculty
biorxiv.org/content/10.1101/…
Very nice! Congrats @AlexanderSobol6 and team!
Ran_Zalk_BGU_Cryo_EM retweeted
Very excited to share our latest study uncovering a functional cross-talk between BRD4 and MITF on chromatin in melanoma cells. A fantastic collaboration with @bernstein_lab, now published in NAR Cancer.
👉 academic.oup.com/narcancer/a…
wow, congrats Ohad Medalia and team!
Ran_Zalk_BGU_Cryo_EM retweeted
Pre-print out from the @SternbergLab with our contribution on the structural side. Great effort from Matt, Egill Tanner and the rest of the team leaded by awesome Sam!
A 1 year effort on my side learning helical reconstruction by cryoEM... 👇
1/16 New pre-print from the Sternberg Lab!
We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77
Ran_Zalk_BGU_Cryo_EM retweeted
🔥🔥🔥🧬 Excited to share our latest paper @NatureComms. A metabolic transport pathway that senses/synchs glucose + Krebs cycle intermediates. rdcu.be/exMbS
🔬 🩺 #metabolism #diabetes #liver #bioenergetics . Kudos to Noa, Ahlam, Aharon & colleagues!
A fun collaboration with Niv Papo and team! @bengurionu on nanobody interactions with PSMA as a prostate cancer targeting approach, below two nanobodies bound to the same target! sciencedirect.com/science/ar…
Ran_Zalk_BGU_Cryo_EM retweeted
New study shows how bacteria evolved powered-up propellers imperial.ac.uk/news/265473/n… ... nature.com/articles/s41564-0…
