Biochemist. Coordinator @ciberdem @IISPereVirgili #Metabolomics Platform. Assistant Prof @etseURV. Affiliated member @IRBBarcelona. Former @scrippsresearch
Tarragona, Catalonia
Joined November 2011
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We’re excited to share our latest work "Improving MALDI Mass Spectrometry Imaging Performance: Low-Temperature Thermal Evaporation for Controlled Matrix Deposition and Improved Image Quality" | Journal of the American Society for Mass Spectrometry pubs.acs.org/doi/10.1021/jas… 🧵👇
Delighted and honored to have participated in this fascinating study led by @ManelEsteller
Excited to share our #multiomics study of who was the world's #oldest living person! Our research on this record-breaking #supercentenarian suggests that, under certain conditions, #aging and #disease can become decoupled—challenging the common belief that they are inherently linked. #longevity #science Enjoy!
biorxiv.org/content/10.1101/…
Oscar Yanes retweeted
ONLY 3 DAYS LEFT for computational biologists ...!
To apply for a PhD position
- on Metabolic Genome Regulation
- in Acute Myeloid Leukemia
- supervised by @tvavouri and me
- at @carrerasIJC
- in Barcelona, Spain
- part of @MSCActions HubMOL
hubmol.eu
Please RT!
🚀 New paper alert! 🚀 Happy to introduce #ChemEmbed, a deep learning framework for metabolite identification that enhances MS/MS data and leverages multidimensional molecular embeddings. A 🧵 on how it works ⬇️ #metabolomics #MachineLearning #DeepLearning
4/ The results:
✅ ChemEmbed ranks the correct metabolite #1 in 42% of cases in a test dataset.
✅ Finds the correct compound in the top 5 in 76% of cases
✅ Against external benchmarks CASMI 2016/2022, and ARUS dataset (human plasma & urine), ChemEmbed outperforms #sirius 6
5/ Want to learn more? 📄 Read our full paper on #bioRxiv: biorxiv.org/content/10.1101/…
#Metabolomics #MachineLearning #DeepLearning #MSMS We’d love to hear your thoughts!
This is another successful collaboration with @sees_lab at @universitatURV
I finally moved to #BlueSky #BlueskySocial Kind of funny to add this in X, but I'll end up quitting this platform. Here's my profile in BlueSky for those interested : bsky.app/profile/oyanes.bsky…
🔬 Read more about how LTE advances the field of MALDI-MSI, including crystal morphology, stability tests, and comparative analysis with spray-coating, in our new preprint: biorxiv.org/content/10.1101/… #MALDIMS #MassSpectrometry #Lipidomics
An ongoing study in our lab focuses on developing new matrices for MALDI-MSI of small molecules (m/z <400) using LTE deposition. We're minimizing matrix background interference while enhancing metabolite ionization and coverage, paving the way for #Spatial #Metabolomics
Oscar Yanes retweeted
I am thrilled to finally share our work on persister cancer cells: we identify distinctive features and actionable #vulnerabilities ⚡️of persister cancer cells (#DTP), and provide mechanistic insight into their low #inflammatory activity:
aacrjournals-org.sire.ub.edu…
👩🔬🧪🔎 ⬇️
Mai oblidaré el teu bon tracte i la confiança que vas dipositar en mi. Joan, sempre t'estaré agraït. DEP 🫶🏼
Amb profunda tristesa, lamentem comunicar la mort aquesta passada matinada del Dr. Joan Guinovart, fundador, exdirector, exinvestigador i professor emèrit de l’IRB Barcelona.
El Dr. Guinovart ha estat una figura clau en l’àmbit de la bioquímica, deixant una empremta inesborrable tant a nivell científic com de gestió. La seva intel.ligència, lideratge i el seu profund humanisme han estat fonamentals per a les persones que hem tingut la sort de compartir camí amb aquest home irrepetible i per al món de la recerca.
Expressem el nostre més sentit condol a la seva família, amics, companys i a tota la comunitat de l'IRB Barcelona.
Joan, la teva absència ens deixa un gran buit, però el teu llegat perdurarà per sempre.
Et recordarem sempre, capità.
