
ALT Figure 8 - Summary and implications for the evolution of metamorphosis. (A) Summary of results obtained from knockdown of chinmo in the first nymphal instar of O. fasciatus. chinmo knockdown results in a reduction in the number of nymphal instars, and enhanced rate of wing pad growth and morphogenesis. Gray lines highlight proposed equivalent instars based on the nymphal and adult patterns. (B) Antagonistic roles of Chinmo and Br in regulating the rate of nymphal wing pad growth. Br promotes allometric growth, while Chinmo expression in the absence of Br leads to isometric growth. (C) Model for the interactions between Chinmo, Br and E93 on nymphal maturation and adult development. (D) The separation of Chinmo and Broad function may have led to the separation of isometric growth during the larval stage and allometric growth and differentiation during metamorphosis in holometabolous insects.





































