@watson_group

Synthetic organic chemistry from the University of St Andrews. Many science, very research.

 St Andrews
watsongroup.wp.st-andrews.ac.uk
Joined June 2019
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Congratulations to @_marekvarga, whose preprint on serotonin-derived ORCAs is now live on ChemRxiv! Have a read: chemrxiv.org/engage/chemrxiv…

Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches of DNA Repair...

The base excision repair enzyme 8-oxoguanine DNA glycosylase 1 (OGG1) plays a central role in maintaining genome integrity and mediating cellular responses to oxidative stress. As such, it represents...

chemrxiv.org
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Another year, another successful group trip to Firbush!
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We have fully-funded PhD positions available in the group in the areas of boron chemistry and catalysis. Email Allan for informal enquiries!
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Really nice work from our colleagues in @TheJohnstonLab !
Angewandte Chemie@angew_chem13 Jan 2025
Enantioselective Synthesis of α-Aryl Ketones by a Cobalt-Catalyzed Semipinacol Rearrangement (Craig P. Johnston and co-workers) @TheJohnstonLab @StAndrewsChem #openaccess 🔓 onlinelibrary.wiley.com/doi/…

Enantioselective Synthesis of α‐Aryl Ketones by a Cobalt‐Catalyzed Semipinacol Rearrangement

A chiral cobalt-salen catalyst has been used under mild, oxidative conditions to generate a cobalt(IV)-bound intermediate that is sufficiently electrophilic to promote an enantioselective 1,2-aryl...

onlinelibrary.wiley.com
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Huge congratulations to @MashaMazhuga who bagged herself a presentation prize at last weeks PGR Symposium!
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Congratulations to John and Tom whose work on germanyl triazoles is now live in BJOC! @BeilsteinInst beilstein-journals.org/bjoc/…

Germanyl triazoles as a platform for CuAAC diversification and chemoselective orthogonal cross-co...

Beilstein-Institut

beilstein-journals.org
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A huge congratulations to the newly minted Dr McGuff on passing his viva yesterday to conclude a hugely successful PhD! @john_mcguff Big thanks to @RhPdCu and @SPThomasGroup for doing the honors!
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New paper in collaboration with our friends in the @BurleyResearch. Congrats to Fred and Andrea! @StAndrewsChem @watson_group pubs.acs.org/doi/10.1021/acs…

Reactivity Profiling for High-Yielding Ynamine-Tagged Oligonucleotide Click Chemistry Bioconjugat...

Abstract. The Cu-catalyzed azide–alkyne cycloaddition (CuAAC) reaction is a key ligation tool used to prepare bioconjugates. Despite the widespread utility

pubs.acs.org
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The current utility and future potential of multiborylated alkanes (@KaneACB, @D_Roberts95, @watson_group, @EPSRCboron): nature.com/articles/s41570-0… (@NatRevChem).
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The current utility and future potential of multiborylated alkanes nature.com/articles/s41570-0… A new Review article from @KaneACB @D_Roberts95 and Allan Watson (@watson_group) at @StAndrewsChem
There has been an accelerating trend to prepare multiborylated alkanes that possess two or more C(sp3)–B bonds but many of these compounds currently offer limited downstream synthetic value

ALT There has been an accelerating trend to prepare multiborylated alkanes that possess two or more C(sp3)–B bonds but many of these compounds currently offer limited downstream synthetic value

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C-B, or not to C-B - that is the question… Check out our review on the utility of multiborylated alkanes in @NatRevChem. Huge congratulations to @KaneACB and @D_Roberts95 for their fantastic efforts! @EPSRCboron @StAndrewsChem nature.com/articles/s41570-0…

The current utility and future potential of multiborylated alkanes

Nature Reviews Chemistry - Monoborylated alkanes display diverse reactivity and broad application; however, despite an increasing number of approaches to access them, multiborylated alkanes have...

nature.com
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Cool beans. Finally out. Congrats to @KaneACB and @D_Roberts95 eur01.safelinks.protection.o… @watson_group
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Watson Group retweeted
Kane Bastick@KaneACB26 Sep 2024
Implicit or explicit? That really is the question (for the synthetic potential of multiborylated alkanes), out now in @NaturePortfolio @NatRevChem (!) Huge thanks @allanjbwatson and @D_Roberts95 for the support on this ‘boron behemoth’ @watson_group tinyurl.com/3dkz34rt
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Really happy to see this out in @NatRevChem with @KaneACB & @allanjbwatson . If you’re interested in the reactivity of borylated alkanes, have a read: nature.com/articles/s41570-0…. @watson_group
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Excited to share that I've received funding from the RSC Inclusion and Diversity Fund to run a series of podcasts aimed primarily at the LGBTQIA+ STEM community. Please share this as widely as possible as I'm looking for podcast interviewees!!
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A great day at the 38th @RSC_HSG postgraduate symposium in Edinburgh (@EdinburghChem)! Group members Tom and @TimHilton98 were in attendance. Tom presented a poster on his work, while Tim presented a prize winning talk!
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Many thanks to the organisers at OSSC 2024! There were many fascinating discussions on chemistry, as well as insightful early career advise! Group members @MashaMazhuga, @TimHilton98, and Tom presented their posters, with Masha picking up a poster prize! #OSSC2024
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A fantastic trip down south for group members @MashaMazhuga, @TimHilton98, and Tom to meet with our @EPSRCboron collaborators in the @an_andrew_leach group! Fantastic discussions and great food, many thanks to Andrew for hosting! #collaborate
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Watson Group retweeted
Tim Hilton@TimHilton9811 Jul 2024
Delighted to have had the opportunity to present some of my work with @watson_group at 9th @EuChemS_Congres in Dublin! 👨‍🔬🇮🇪 Experienced some amazing chemistry talks, and had some brilliant discussions with other researchers, often with a Guinness.
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Fantastic day yesterday for the annual @RSCPerkin meeting, this year at @dundeeuni. Plenty of brilliant talks and posters, not least from our own @TimHilton98 and @MashaMazhuga! @DDU_Dundee @StAndrewsChem
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