Biologist, amateur yogi, runner, experimental cook, #environmentalist, Postdoc @PennMedicine, ATPases, ubiquitin, DNA replication-repair

Philadelphia, PA, USA
Joined July 2014
Very excited to see our work on replisome proteostasis by 55LCC published in @CellCellPress . Great collaboration with @FoglizzoMartina @zeqiraj @RobertLDilley @arindam_datta1
We're excited to report a new mechanism of replisome proteostasis cell.com/cell/fulltext/S0092…. 55LCC ATPase/unfoldase complex dependent replisome turnover prevents chromosome instability. Great collaboration by @vidhya_k7 and @RobertLDilley with @FoglizzoMartina and @zeqiraj.
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The Zhang Lab website is online now: ztplab.com. We are interested in Genome Integrity Maintenance within Repetitive Sequences.
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Thrilled to share the first manuscript from Verma Lab! We uncover that cleavage of abasic sites represents a new approach to enhance PARP inhibitor sensitivity. Thankful to the perseverance and hard work of my students @natasha_m_r and @LindseyA2000 rdcu.be/dPbsT
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I’m thrilled to share that I will be joining Department of Radiation Oncoloy (and BMG) @UVA as AP this August. The Zhang Lab will study genome integrity maintenance within repetitive genome regions. I am grateful to the mentorship from postdoctoral supervisor@RogerRogergr and
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Our recent study was featured as cover story on Molecular Cell. @HaoyangJiang2 is not only great scientist, but also excellent artist.
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In the latest issue! The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity dlvr.it/T62wmd
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We are thrilled to share our latest studies showing how BLM helicase drives ALT (alternative lengthening of telomeres). A great teamwork with Dr. Haoyang Jiang @HaoyangJiang2; again, a lot of fun collaboration with Dr. Patrick Sung team @PatrickSungLab.
Please see our latest findings on how BLM helicase orchestrates the damage response that executes Alternative Lengthening of Telomeres. cell.com/molecular-cell/abst…. Great work from Haoyang @HaoyangJiang2 and Tianpeng @zhtianp2 in collaboration with Hardeep Kaur and Patrick Sung.
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Excited to report our findings on how BLM helicase promotes alternative lengthening of telomeres. Amazing teamwork with Tianpeng (@zhtianp2) and thank everyone from Roger’s lab (@RogerRogergr UPENN) and Patrick’s lab (@PatrickSungLab UTHSCSA)! doi.org/10.1016/j.molcel.202…
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Please see our latest findings on how BLM helicase orchestrates the damage response that executes Alternative Lengthening of Telomeres. cell.com/molecular-cell/abst…. Great work from Haoyang @HaoyangJiang2 and Tianpeng @zhtianp2 in collaboration with Hardeep Kaur and Patrick Sung.
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New research identifies a key quality-control mechanism in DNA replication ft. @RogerRogergr, @vidhya_k7, @RobertLDilley (@Penn_CBIO/ @PennCancer/ @PennGenomeInteg), @zeqiraj & @FoglizzoMartina (@UniversityLeeds) tinyurl.com/55rufukv
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Vidhya K retweeted
Now online! The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity dlvr.it/T51Ghw
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So delighted to see this beautiful work out! Well deserved recognition for all the hard work by @vidhya_k7 @RobertLDilley @RogerRogergr
We're excited to report a new mechanism of replisome proteostasis cell.com/cell/fulltext/S0092…. 55LCC ATPase/unfoldase complex dependent replisome turnover prevents chromosome instability. Great collaboration by @vidhya_k7 and @RobertLDilley with @FoglizzoMartina and @zeqiraj.
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Big thanks to @RogerRogergr and everyone in the Greenberg lab!
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We're excited to report a new mechanism of replisome proteostasis cell.com/cell/fulltext/S0092…. 55LCC ATPase/unfoldase complex dependent replisome turnover prevents chromosome instability. Great collaboration by @vidhya_k7 and @RobertLDilley with @FoglizzoMartina and @zeqiraj.
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Important work from Shane Harding and colleagues on the proteomic landscape of micronuclei:
Online Now: The proteomic landscape of genotoxic stress-induced micronuclei dlvr.it/T3N99F
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BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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Please RT! The 2nd ‘Genome Instability: Discovery to Personalized Medicine’ meeting in #Philadelphia is on Nov 3rd! Focusing on #DNArepair topics it spans basic research to drug development to clinical trials. Abstracts due Sept 15th! See link to register! noncredit.temple.edu/genomec… – at Philadelphia, PA
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