Computational Biology PhD candidate at @BrownCCMB | Huerta-Sánchez lab | BSc Genomics @UNAM_MX | ancient and modern admixture, complex traits | she, her

Joined March 2020
Valeria Añorve-Garibay retweeted
Alessandro and I discussed this great paper science.org/doi/10.1126/scie… that investigates a deleterious genetic interaction that causes melanoma.
NEW content online! Discovering genetic interactions that cause melanoma in a non-model species bit.ly/4nSGDaF
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Valeria Añorve-Garibay retweeted
🇵🇹Our paper on Portugal's genetic history is now published in @GenomeBiology. We present the largest collection of ancient Portuguese genomes, with deeper analyses than our pre-print, revealing migrations, admixture and remarkable continuity doi.org/10.1186/s13059-025-0… @TeixeiraJoaoC
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Valeria Añorve-Garibay retweeted
Our paper is out! Happy to have collaborated with @mashaals , @emiliahsc and @valenomics on this project. Here we analyzed how stabilizing and directional selection cause problems to predict traits in ancient samples.
The paper is out in @AJHGNews!!! “Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples”. Read it here: kwnsfk27.r.eu-west-1.awstrac…
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Valeria Añorve-Garibay retweeted
Our work is out in AJHG "Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples." Great collaboration with @dortega_delv & @emiliahsc, led by talented @lcgejunam undergrad @valenomics, now a PhD student at @BrownCCMB.
The paper is out in @AJHGNews!!! “Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples”. Read it here: kwnsfk27.r.eu-west-1.awstrac…
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The paper is out in @AJHGNews!!! “Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples”. Read it here: kwnsfk27.r.eu-west-1.awstrac…
I am stoked to announce that my first first-author preprint is out!! 🎉 doi.org/10.1101/2024.09.10.6… I started this work as an undergrad student in @dortega_delv lab in collaboration with @mashaals and @emiliahsc. Summary ⬇️
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and endless thanks to @dortega_delv, @mashaals, and @emiliahsc for their support throughout this work!
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Valeria Añorve-Garibay retweeted
📣New from Añorve-Garibay et al! 📄Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples cell.com/ajhg/abstract/S0002…
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Valeria Añorve-Garibay retweeted
Honored and humbled to be mentioned for my contributions in human evolutionary genetics. Thanks @emiliahsc for the shout out to our work in this piece highlighting women’s contributions to science. nature.com/articles/s41562-0…
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Valeria Añorve-Garibay retweeted
Nice collaboration with Luliana Lonita-Laza's group at Columbia. "Fine-mapping in admixed populations using CARMA-X, with applications to Latin American studies" now out in @AJHGNews @scientist_ninja @valenomics authors.elsevier.com/c/1kqIJ…
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Valeria Añorve-Garibay retweeted
¡La convocatoria para el ingreso a la Licenciatura en Ciencias Genómicas que se imparte en el Campus Juriquilla de la UNAM ya está disponible! ¡A partir de hoy puedes registrarte para el proceso interno de ingreso y ser parte de la 8ava generación de la #LCGEJ! @lcgejunam 🧬🥼💻
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Valeria Añorve-Garibay retweeted
Dr. @lisatoafault shared so many wisdom pearls! Emilia and Rori share their lessons from this amazing conversation in the new bonus episode, out today! 🎧 pod.link/1715048894 Listen wherever you get your podcasts!
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Valeria Añorve-Garibay retweeted
Si me dieran a elegir, volvería a ser científica. También volvería a encontrar a las amigas para acompañarnos, aprender y desaprender cosas. Las abrazaría más. Elegiría siempre aprender del mundo y tratar de analizarlo hasta el nivel más pequeño, literalmente.
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Valeria Añorve-Garibay retweeted
Season Two starts NOW! 🚀 Dr. @MEOrive joins us for #WomenInScienceDay and shares her academic journey - from finding her path in science to earning tenure✨ This convo is full of honesty and thoughtful insights! Listen now! 🎧 pod.link/1715048894
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📢Online now! 📰Genome-wide maps of highly-similar intrachromosomal repeats that can mediate ectopic recombination in three human genome assemblies 🧑‍🤝‍🧑@cgonzagaj @CMBCarvalho & colleagues 👉bit.ly/3DBKbMt
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Valeria Añorve-Garibay retweeted
LIIGH investigator @cgonzagaj and @lcgejunam student Luis Fernandez-Luna in collaboration with investigators from @PNRIGenetics and @bcmhouston just published a new article cataloguing and analyzing highly similar repeated sequences in the human genome @HGGAdvances Read it here👇🏽
📢Online now! 📰Genome-wide maps of highly-similar intrachromosomal repeats that can mediate ectopic recombination in three human genome assemblies 🧑‍🤝‍🧑@cgonzagaj @CMBCarvalho & colleagues 👉bit.ly/3DBKbMt
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Valeria Añorve-Garibay retweeted
I am proud to share our latest paper📜 “The multi-scale complexity of human genetic variation beyond continental groups”, just pre-printed on @biorxivpreprint! Link Here ➡️biorxiv.org/cgi/content/shor…
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I am stoked to announce that my first first-author preprint is out!! 🎉 doi.org/10.1101/2024.09.10.6… I started this work as an undergrad student in @dortega_delv lab in collaboration with @mashaals and @emiliahsc. Summary ⬇️
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In addition, our simulations showed that both types of selection can hamper polygenic scores accuracy for traits like height and BMI, despite having complete genotype data and perfect effect size estimates. 6/7
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Natural selection can provoke substantial biases in predicting complex traits from ancient genomes using polygenic scores, so it’s crucial to consider its impact when predicting complex traits! 7/7
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