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JUST IN: JPMorgan helps Solana develop new system allowing financial institutions to settle trades onchain in seconds.
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NYC now legally requires companies to make cancelling a subscription as simple as signing up, the first US city to do so
"If you can sign up with a click, you must be able to cancel with one," Mayor Zohran Mamdani said
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MERCK $MRK AND MODERNA $MRNA JUST HIT THE FIRST POSITIVE PHASE 3 RESULT EVER FOR A PERSONALIZED CANCER VACCINE
Their Phase 3 INTerpath-001 trial found that "intismeran autogene, an mRNA therapy custom-built from each patient's own tumor mutations, combined with Merck's KEYTRUDA, significantly improved recurrence-free survival and distant metastasis-free survival versus KEYTRUDA alone in patients with completely resected stage IIB-IV melanoma."
This is the first Phase 3 readout ever for an individualized neoantigen therapy, and the first Phase 3 study to beat KEYTRUDA alone as a standard-of-care adjuvant treatment for resected melanoma.
Merck and Moderna will present full data at an upcoming medical meeting and begin talking with regulators about filing submissions.
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JUST IN: BlackRock believes allocating 1-2% to Bitcoin will improve long-term portfolio returns.
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$KO is having its best day since 2009 after its Q2 earnings report blew past investor expectations.
Coca-Cola Zero Sugar drove sales, with volume up 16% in the quarter. Right behind it were Diet Coke and Coca-Cola Light, up 7%.
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We all know the "Undo Send" button for those accidental, overzealous emails... but did you know you can customize how long it stays on screen? Give yourself up to 30 seconds of breathing room to catch that typo (because nobody’s perfect).
Settings ⚙️ ➔ General ➔ Undo Send
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U.S. dollar has lost roughly 28–30% of its purchasing power over the past six years, according to inflation data.
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Stanford has just leaked this free class that explains how claude and chatgpt work from the inside
The majority wastes 90% of its potential
Stanford teaches it to you in 1h50 minutes
Save this to favorites so you don’t lose it.
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My first interview with @sama, Co-Founder of @OpenAI.
0:04 How to start a startup
3:30 Trusting exponentials
4:57 Operating in chaotic environments
6:12 Learning to enjoy painful experiences
8:03 Creating abundant intelligence
11:15 Keeping core suppliers on OpenAI’s timelines
12:10 Invention of the joint-stock company
15:30 The best CEOs aren’t sociopaths
16:46 We are in the singularity
18:09 AI authoritarianism vs liberty
19:24 Texting 300-400 people a day
20:32 Having a small number of deep beliefs about the future
21:41 Critical path
22:25 Thinking about what’s next
23:38 Getting on planes in marginal situations
28:16 Buying lots of compute
30:51 Ambition
34:00 Google shouldn’t have let OpenAI survive
37:54 Having his life shot through a cannon after the launch of ChatGPT
41:20 The growth of Codex
42:02 The Death Star tweet
44:46 Status games and desire to be useful
47:57 Not being ambitious enough on compute investments
50:26 Execution
51:45 Ask for what you want
54:11 First few weeks of OpenAI
55:15 Shutting down Sora to focus on Codex
57:44 Designing beautiful products
59:01 Getting addicted to TikTok
1:01:03 Inventing a new device
1:02:53 Try to get better at your strengths
1:05:57 Masa is an n of 1
1:07:11 Real trends vs fake trends