PhD structural biologist @UofT studying #AMR antimicrobial resistance, #covid19 and protein engineering. #Science is the last best hope of humankind.

Toronto, Ontario
Joined February 2010
Inspiring little article.
How I learned to teach like a scientist Recently retired, this professor emeritus reflects on how she challenged students to think beyond facts. #AcademicChatter bit.ly/4bseH91
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We found one amino acid in particular that it’s important for the particular RNA methylation necessary for multi-drug resistance. We still have a lot more to learn about this enzyme, including experimental structure determination of a Cfr-RNA complex.
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Thanks to Michael Fruci @AAFC_Canada, @FujimoriLabUCSF, @UCalgary, the Center for Structural Biology of Infectious Diseases @microprofmom @NIAIDNews and @argonne! 🧵
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Interesting twist. It has long been known that addition of rRNA modifications can lead to AMR, it’s interesting to see the opposite is also true. I wonder if there are rRNA methylhydrolases out there that are undiscovered.
Antibiotic Resistance Can Emerge If Bacteria Lose rRNA Modifications Antibiotic resistance study explores a recently identified mechanism in bacteria: the shedding of methylation marks from ribosomal RNA. hubs.li/Q02ZYmCd0
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I’m looking forward to convening the session “New Insights into Molecular Mechanisms of AMR” and presenting my research at #ASMicrobe tomorrow morning! Closing out the meeting with a “bang” 😉
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Truth
The scale of this cartoon is way off, but if it was accurate, the last column would be less than 1 pixel
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Looks just about like most of my talks 😉
A quick pie chart that I totally didn't make at the last minute...
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Peter J Stogios retweeted
I enjoy meetings a lot more if no one can see what I'm doodling 🐍
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Peter J Stogios retweeted
I love writing meeting plans, I just wish they had more dragons in like other fantasy stories
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Peter J Stogios retweeted
"Interesting presentation but how do you think your imprinted polymer nanoparticles could be applied to the study of 1300s agrarian land use in Latvia?"
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We are working with @GoogleDeepMind to use #AI to do advanced modelling and analysis of several proteins identified as promising but unrealised targets for new #antibiotics 💊 gardp.org/gardp-google-deepm…
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I would love to know what percentage of my life is spent pressing “Report Spam” as I receive countless spam “conference invitations” and “journal invitations”. No I’m not interested in chairing a conference on a field of science I have never participated in any way ever.
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Peter J Stogios retweeted
Cyanobacteria invented photosynthesis billions of years ago. Now, scientists have fossil evidence of the structures needed to turn sunlight into chemical energy in some ancient cyanobacteria. sciencenews.org/article/bact…
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Congratulations! Yet another example of how basic science research is essential for development of products that benefit humanity—even when the researchers don’t know it at the time and exploring their curiosity—that’s how the best science works.
BREAKING NEWS The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
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Replying to @DanielGriffinMD
@DanielGriffinMD could I get your help with my experience with Paxlovid? I got symptomatic COVID, tested positive on rapid test, immediately started taking Paxlovid. After 6 days test was negative and my symptoms were gone. I felt good, tested negative two days in a row. Cont’d
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Two days after that, my symptoms came back, I’ve tested positive again for 3 says and I feel worse than the first days with Paxlovid. Vincent said I’m in the inflammatory phase, so that makes sense, but why am I getting virus replication again? Should I be worried? Thank you!
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