@theMaxwellLabi
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Phage biologist focused on virus-host interactions and bacterial pathogenesis.
Toronto, Ontario
Joined January 2016
- Tweets2.2K
- Following225
- Followers1.8K
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Karen Maxwell retweeted
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases.
I'm trying to understand non-surgical chemo and targeted therapy options, new pathology markers to better diagnose subtypes/treatments, and any data on progression in pediatric patients. Please feel free to share – I’m trying to cast a wide net due to the rarity of this condition and how little is known.
People can contact me directly at my first name (as written in my profile) at octant.bio.
Karen Maxwell retweeted
New paper with @theMaxwellLab :
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication
doi.org/10.1128/mbio.02466-2…
Amazing work by @LandonGetz and team!
This Post is from an account that no longer exists. Learn more
There are people that submit their grants more than 8 minutes ahead of the deadline???
Karen Maxwell retweeted
🚨New preprint from our lab! We map the RNA interactions in E. coli infected by lambda, revealing an RNA-driven regulatory layer in phage-host dynamics. We find a phage-encoded sRNA hijacking host replication machinery, impacting the phage cycle.#microbiology #phages @MeetingRna
Phage-encoded small RNA hijacks host replication machinery to support the phage lytic cycle biorxiv.org/cgi/content/shor… #biorxiv_micrbio
Karen Maxwell retweeted
We’re here at @WCHospital for the #GairdnerScienceWeek Women of Gairdner Event!
High school students, researchers and local faculty are here with 2024 Canada Gairdner Award laureates Drs. Meghan Azad, Gagandeep Kang, and 2022 #GairdnerAwards winner Dr. Deborah Cook
Watch the webinar now! us02web.zoom.us/webinar/regi…
Karen Maxwell retweeted
Please RT. 1x postdoc and 1xPhD position available in our group to study the role of NLR-like proteins in cellular development and antibiotic production in Streptomyces.
Postdoc: shorturl.at/f8NTN
PhD position: shorturl.at/qCFmN
Email me for more information.
Karen Maxwell retweeted
This was a wonderful meeting @SPP2330 again! Great kick-off of our second funding period!
Amazing science going on in the phage field and great to see students/postdocs from the first funding period starting their independent labs.
@dfg_public, @fz_juelich, @HHU_de
Karen Maxwell retweeted
Julia Frunzke @FrunzkeLab opening the annual @SPP2330 meeting! Looking forward to 3 exciting days of science! @dfg_public
Karen Maxwell retweeted
We are ready to go for the Annual SPP2330 Meeting on “New Concepts in Prokaryotic Virus-host Interactions”! With a fantastic line up of speakers: Alexander Harms @AHarms485, Karen Maxwell @theMaxwellLab, Samuel Kilcher @SamuelKilcher, and Mathias Middelboe @mmiddelboe1
Karen Maxwell retweeted
Rare opportunity to join my team, as the @PLOSBiology in-house editorial team is growing!
It's a great team in a great journal, if I say so myself 😆
Please reach out if your have Qs & apply if interested!!
UK or US; assoc or senior
Please RT
us241.dayforcehcm.com/Candid…
Karen Maxwell retweeted
A supervisor, postdoc and the new PhD candidate
nitter.cf/i/status/1808987434752…
Karen Maxwell retweeted
Congratulations to @UofT_dlsph postdoc fellow @michelle_olding on receiving the 2024 EPIC Career Transition Award to lead an independent project looking at the role of prescribed safer supply programs in improving access to HIV and HCV care!
Read more: bit.ly/45x0Quk
Karen Maxwell retweeted
Anti-phage defence through inhibition of virion assembly
@theMaxwellLab @pramalpatel
#phages #antiphage #prophages #phagedefence
#bacteria #microbiology #virology
nature.com/articles/s41467-0…
This is definitely one of the longest running projects in the lab b/c we were stuck in a trap of thinking about Sie proteins blocking competing phages. But wasn't a satisfying answer to fit the biology we observed - kudos to @vee_coli for persevering and figuring it out!
New prepint alert @themaxwelllab! 📢 📢 📢 Superinfection exclusion (Sie) proteins aren’t just for defence – they also ensure the spread of viral progeny! Prophages that lack Sie proteins devour their young via a process we call the Kronos effect.
biorxiv.org/content/10.1101/…
Karen Maxwell retweeted
New prepint alert @themaxwelllab! 📢 📢 📢 Superinfection exclusion (Sie) proteins aren’t just for defence – they also ensure the spread of viral progeny! Prophages that lack Sie proteins devour their young via a process we call the Kronos effect.
biorxiv.org/content/10.1101/…
Karen Maxwell retweeted
I am thrilled to share our work on a novel prophage-encoded phage defence from @theMaxwellLab:
Anti-phage defence through inhibition of virion assembly
nature.com/articles/s41467-0…
This old dude band’s cover of Tiffany’s “I think we’re alone now” made.my.year.
Karen Maxwell retweeted
Out today in @MolMicroEditors:
Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in P aeruginosa
doi.org/10.1111/mmi.15202
With our 🇨🇦 friends @DezielEric and @theMaxwellLab
Karen Maxwell retweeted
Congratulations to Gary Bader, Benjamin Blencowe, Timothy Hughes and Mikko Taipale on their chair appointments! 👏
The appointments will support research in disease biomarkers, gene regulation and host-pathogen interactions. #UofT
Learn more 👉 uoft.me/ChairAppointments