@tharagai

A Geriatrician with a blend of practicality & heuristic aptitude.

 Brisbane, Australia
Joined July 2009
  • Tweets4.8K
  • Following4.3K
  • Followers2K
343Media
I have 9 new followers from Singapore 🇸🇬, and more last week. See fedica.com/!tharagai
User report

ALT User report

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Kannan Natarajan retweeted
Andy Teodorczuk@andyteodorczuk8 Nov 2024
Andy Teodorczuk@andyteodorczuk8 Nov 2024
Bridget Riggs from ⁦@ANZDA_delirium⁩ explains that NuDesc may be more appropriate when assessing #delirium in a person from an Aboriginal and Torres Strait Islander background. “I see you are seeing something out there. Is it deadly?”
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Replying to @SyncopeJohn
@syncopejohn #HunterGeriatrics2024 #DevilInTheDetail @RoseAnnekenny1 #ECG #BBB #PosturalBP #RiskStratification #24BP #TTT #RecurrentSyncopeWithoutProdrome #UnawarenessOfHypotension #InjuriousSyncope #DrivingCritical differentiate VVS vs. #FND tinyurl.com/46tyzj2u
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#OrthostaticHypotension - #GeriatricianScalpel #Polypharmacy #Hydration #BalletToes #Fludrocortisone caveats ++ in older patients. #Midodrine #Beware #CerebroCardioVascular #Pyridostigmine #TolerabilityChallenges #Atomexetine #ShortTermBenefit #Salt - #NO tinyurl.com/y6467sj

Pyridostigmine bromide versus fludrocortisone in the treatment of orthostatic hypotension in...

Pyridostigmine bromide is inferior to fludrocortisone in the treatment of OH in PD. This trial provides first objective evidence of the efficacy of 0.2 mg/day fludrocortisone for OH in PD, causing...

pubmed.ncbi.nlm.nih.gov
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onlinelibrary.wiley.com/doi/… pubmed.ncbi.nlm.nih.gov/3260… pubmed.ncbi.nlm.nih.gov/2910…

Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension

Objective The efficacy and safety of 1-month atomoxetine and midodrine therapies were compared. Three-month atomoxetine and combination therapies were investigated for additional benefits. Methods ...

onlinelibrary.wiley.com
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#VVS management neurally mediated - explain the mechanism. Conservative - optimise H2O, evidence not good for compression garments. Abdominal binders not tolerated well by people at old age. Modest effects with meds. Simple things done well is much better than fancy things.
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academic.oup.com/eurheartj/a… @escardio
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Replying to @DrElieMatar
@DrElieMatar advised the audience to watch out for the evolving biological definitions in #LewyBodies #HunterGeriatrics2024 #alphasynuclein #NSDISS #TanyaSimuni #KenMarek @YNHH #SynNeurGe @GunterHoglinger #AnthonyLang @KBI_UHN (...1)
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#EkTan @dukenus talked about the genetic discoveries to clinical discoveries in #ParkinsonsDisease #HunterGeriatrics2024 #Cinpanemab #Prasinezumab #SmallMoleculeKinaseInhibitors
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genetic discoveries to clinical trials.
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Replying to @KRayChaudhuri1
@KRayChaudhuri1 master class on #Cholinergic subtype of #ParkinsonDisease & the system changes impacting cognition-other non motor factors #HunterGeriatrics2024 #Freezing #IdiopathicConstipation #CamPaIGN @padmakumarc2 @profsimonlewis @DrISubramanian
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sciencedirect.com/science/ar… #JacobHorsager pmc.ncbi.nlm.nih.gov/article…
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#VictorFung @movedisorder @kalialabs @GunterHoglinger @Anna_Sauerbier walked through the current understanding & complex challenges with the clinical vs. biological definitions of #ParkinsonsDisease #HunterGeriatrics2024 #SeedAmplificationAssay #AlphaSynnuclein #ProteinClearance
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Replying to @Sydney_Uni
@Sydney_Uni #ProfGlendaHalliday disentangling the #alphasynuclein #tauaggregates #FriendsOrFoes #HunterGeriatrics2024 Pathologically IIIr phenotypes but diff. temporal sequences. Prevalent #pTau deposition with age. #pTau seems more prevalent only in #LRRK2 #RNABP #seedingassays
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Foes!
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#ProfShenYangLim delineating the #PSP phenotype variation #HunterGeriatrics2024 @citynewcastle highlighting the works of @KRayChaudhuri1 @GunterHoglinger #ProfAdamBoxer @Brodmann87 #NormalPressureHydrocephalus harbinger for #PSP @AlbertoEspay #EthnicDifferences @kailashbhatia
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#ProfShenYangLim elaborating the genetic variants in #PSP #MAPT #GBA1 #LRRK2 thelancet.com/journals/laneu… @TheLancetNeuro #GP2 gp2.org/

Uncovering the genetic basis of Parkinson's disease globally: from discoveries to the clinic

Knowledge on the genetic basis of Parkinson's disease has grown tremendously since the discovery of the first monogenic form, caused by a mutation in α-synuclein, and with the subsequent identifica...

thelancet.com
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Replying to @DrEmHenderson
@DrEmHenderson sets agenda 4 #ParkinsonsDisease in #OlderAdults #complexity #courage #care #HunterGeriatrics2024 @citynewcastle #HealthRelated #QoL #SystematicReview #JanetvanUem @EmmaTenison t.ly/tTS97 @PdPrime #STRIPE trial. Watch #CHIEFPD t.ly/TipDi
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@PdPrime #RCT #StratifiedMDTCare #SinglePointOfAccess #IndividualisedGoalAttainment #WhatMatters Care can be #DiseaseModifying @TheLancet thelancet.com/journals/lance…

What next in Parkinson's disease?

More than 200 years since the publication of James Parkinson's An Essay on the Shaking Palsy (1817), many uncertainties regarding the progressive neurological disorder now known by his name remain....

thelancet.com
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Replying to @meera_agar
@meera_agar illustrates that distress in palliative care is complex and anchors @A_MacLullich @dhj_davis @ZoeTieges article @Age_and_Ageing guidance #HunterGeriatrics2024 @CityNewcastle #DistressThermometer #PROMIS
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doi.org/10.1093/ageing/afac2…

Three key areas in progressing delirium practice and knowledge: recognition and relief of distress,...

Abstract. Delirium presents formidable challenges: it affects one in four of older hospitalised adults, greatly elevates the risk of multiple short- and lo

academic.oup.com
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@victoriamgibson #HunterGeriatrics2024 @CityNewcastle explains how to better represent frailty when assessing surgical risk through the #CARESClinic Comprehensive Assessment REview & Shared-decision making experiences #HawkesBay @TeWhatuOra @HQSCNZ #Tewairuhi #TeaoMaori #kaumatua
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@vickymgibson #HunterGeriatrics2024 @CityNewcastle
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Is it time for @ICD11 coding #Frailty similar to #MultiMorbidity #HunterGeriatrics2024 @CityNewcastle @JKDhesi @TomPoulton @monashperiopmed @ANZCA @AislingFleury
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