LEO Foundation Skin Immunology Research Center retweeted
Can a cancer exploit its environment and still resist treatment?
Yes, through co-existing malignant subclones!
Let me walk you through our latest study on how divergent evolution drives aggressiveness, and drug resistance of T cell cancer. 1/🧵
doi.org/10.1158/2159-8290.CD…

ALT Schematic figure showing divergent evolution of malignant subclones and how they migrate to different tissue compartments (blood vs skin), respond differently to extrinsic stimuli such as Staphylococcus aureus enterotoxins, and how subclones differ in their intrinsic resistance to anti-cancer drugs.
LEO Foundation Skin Immunology Research Center retweeted
Now online in @CD_AACR: Divergent Evolution of Malignant Subclones Maintains a Balance Between Induced Aggressiveness and Intrinsic Drug Resistance in T Cell Cancer - by @TerkildB, Niels Ødum and colleagues doi.org/10.1158/2159-8290.CD… @UCPH_Research @skinUCPH
Registration for the SIC summer school May 12-14 2025, in Hornbæk Denmark, opens on the 1st of December! Check sic.ku.dk/summerschool for preliminary programme. @jonatcoquet @LEOFondet
LEO Foundation Skin Immunology Research Center retweeted
Today we are excited to announce this year’s LEO Foundation Dr Abildgaard Fellows worth DKK 12 million. Congratulations to all four fellows on this incredible achievement. Read more here: shorturl.at/kV1JQ
Huge congratulations to Wenning Zheng at @skinucph for being awarded the Dr Abildgaard Fellowship! We look forward to following Wenning’s project over the next five years. @LEOFondet @liveidsmo @jonatcoquet
Bioinformatician Wenning Zheng, Postdoc at the @skinucph , University of Copenhagen, has been awarded the LEO Foundation Dr Abildgaard Fellowship, worth DKK 12 million.
Read more about her research here: leo-foundation.org/en/2024/1…
LEO Foundation Skin Immunology Research Center retweeted
Bioinformatician Wenning Zheng, Postdoc at the @skinucph , University of Copenhagen, has been awarded the LEO Foundation Dr Abildgaard Fellowship, worth DKK 12 million.
Read more about her research here: leo-foundation.org/en/2024/1…
LEO Foundation Skin Immunology Research Center retweeted
Congratulations to @skinucph on yet another successful #SICSpringtimeSchool!
The talented researchers were invited to an intense three-day learning experience on skin and immunological skin disease research.
Learn more about SIC: sic.ku.dk/
📸Kim Matthäi Leland
Highlights from @TerkildB and @ChellaKrishnaV study published in blood - check the thread for more details!
Can bacterial infections make cancer cells resistant to treatment? In Sézary Syndrome (SS), it turns out they can!
Want to know more? I will summarize some highlights from our recent study @BloodJournal below.
doi.org/10.1182/blood.202302…
New @BloodJournal study by @ChellaKrishnaV and @TerkildB from Niels Ødum’s group @skinucph show bacterial infections can make cancer cells resistance to anti-cancer drugs #Staphaureus #bacteria #CTCL #Cancer #drugresistance
Targeting bacteria, their toxins, and downstream signaling pathways in malignant T cells abrogate the induction of drug resistance. ow.ly/xrt850ReqcE #lymphoidneoplasia #immunobiologyandimmunotherapy
LEO Foundation Skin Immunology Research Center retweeted
I was ever so delighted for another opportunity to participate at #SICSpringtimeSchool. I formed a lot of new connections that may someday lead to fruitful collaborations, and I am honoured to say that my presentation won one of two prizes for best short talk. 🏅 🥳
LEO Foundation Skin Immunology Research Center retweeted
The Best Short Talk Award was definitely the icing on the cake! 🤩 Happy to bring the science from the @MMittelbrunn lab. Thanks from the bottom of my heart to @skinucph for such an inspiring experience at the #SICSpringtimeSchool 2024!
LEO Foundation Skin Immunology Research Center retweeted
@c_schlapbach kicking us off on day 3 of the SIC springtime school @skinucph
LEO Foundation Skin Immunology Research Center retweeted
Great couple of days in Denmark for skin immunology & more 🚲 🇩🇰 🍷 🧬 Thank you @skinucph @StridLab 🤍☺️ #sicspringtimeSchool
LEO Foundation Skin Immunology Research Center retweeted
@BekkerJensenLab kicking off day 2 at the SIC springtime school @skinucph
LEO Foundation Skin Immunology Research Center retweeted
Cosy atmosphere at the #SICSpringtimeSchool @skinucph
LEO Foundation Skin Immunology Research Center retweeted
@ejvillablanca presenting at the SIC Springtime school. Following on from Bill Agace to give us the intestinal barrier perspective @skinucph
Springtime School is finally here! Laura Mackay and Shawn Demehri have kicked off our first of five sessions. Follow our LinkedIn profile for live updates and insights over the coming three days!
📷@kimcml
LEO Foundation Skin Immunology Research Center retweeted
Charlotte Menne Bonefeld from the University of Copenhagen presents their Original Article published in Allergy
Meisser SS, Mitamura Y, Altunbulakli C, et al. Regulation of immune response genes in the skin of allergic and clinically tolerant individuals exposed to p-phenylenediamine. Allergy. 2024;
Read the article here: doi.org/10.1111/all.16031
Watch videos of recent discoveries: journalallergy.com and youtube.com/Allergy-TV
@skinucph @UCPH_health
youtube.com/watch?v=jRNPDsg3…
LEO Foundation Skin Immunology Research Center retweeted
Study from Professor Niels Ødum at @skinucph at @koebenhavns_uni published in @theJIDJournal! New substance can treat staphylococcus infections in people with skin lymphoma. Supported by LEO Foundation.
jidonline.org/article/S0022-…
@UCPH_Research @UCPH_health #dkforsk #dermtwitter
Congratulations to @TerkildB with his Dr Abildgaard Fellowship from @LEOFondet !
I am very excited and truly honored to receive one of the first three Dr Abildgaard Fellowships from @LEOFondet to establish my research group at @skinucph!
I am very grateful to the LEO Foundation for making this dream a reality!






























