@simoado

Affiliate Professor at @UniTrieste. Former postdoc in the Nitschke group @ChemCambridge. PhD in the @MarchesanLab @UniTrieste.

 Cambridge, England
Joined August 2011
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Not a bad way 2 start the week! Grateful to the @RoySocChem for supporting my research through an Research Fund grant. This grant will support my project, "Chiral AuNPs templated by self-assembling peptides for antimicrobial response". Looking forward 2 developing this work.🧪
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Our review on peptide-based supramolecular cages is finally out in @ChemicalScience #diamond #openacces🎉 Thanks to Prof. Nitschke and Prof. Marchesan for their support, and to @xuhy0914 for the jolly collaboration. @ChemCambridge and @DSCF_UniTS pubs.rsc.org/en/content/arti…

Peptide cages: bioinspired supramolecular architectures for next-generation applications

This review examines the design and synthesis of peptide-based supramolecular cages, highlighting the versatility and functional diversity achievable by in

pubs.rsc.org
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The review compares cages built entirely from peptides, where structure is encoded in the sequence, with hybrid architectures in which a pre-organised scaffold defines the shape and peptides add selectivity and responsiveness, highlighting opportunities across different fields.
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Simone Adorinni retweeted
Chemistry Europe@ChemEurope22 Jul 2025
#ChemBioChem Self-assembling peptides direct the synthesis and organisation of gold nanoparticles, with sequence and assembly conditions tuning morphology, chirality and properties (@simoado and co-workers) #openaccess 🔓 onlinelibrary.wiley.com/doi/…

Gold Nanoparticles Guided by Self‐Assembling Peptides: From Sequence to Superstructure

Self-assembling peptides act as versatile templates for gold nanoparticle (AuNP) synthesis. Their organization into discrete nanostructures or hydrogels enables control over AuNP morphology and...

chemistry-europe.onlinelibrary.wiley.com
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Thrilled to share my first paper doi.org/10.1002/cbic.2025003… as corresponding author in #ChemBioChem @ChemEurope. In this concept review we discuss how self-assembling peptides control gold nanoparticle nucleation growth and organisation.

Gold Nanoparticles Guided by Self‐Assembling Peptides: From Sequence to Superstructure

Self-assembling peptides act as versatile templates for gold nanoparticle (AuNP) synthesis. Their organization into discrete nanostructures or hydrogels enables control over AuNP morphology and...

chemistry-europe.onlinelibrary.wiley.com
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The second explores peptide gels as soft 3D matrices where NPs nucleation and growth occur in situ within a macroscopic yet nanostructured environment. This work illustrates how rational peptide design enables control over the structure and properties of peptide–AuNP materials.
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The review examines two complementary strategies for templating gold nanoparticles with self-assembling peptides. The first relies on discrete supramolecular assemblies that act as nanoscale scaffolds, enabling precise organisation and chirality transfer.
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Had a fantastic time in Glasgow for @Faraday_D on supramolecular gels, great to meet so many leaders in the field. Grateful to the organisers for the chance to present my work and to @SupraChem for the 1st Gen Travel Grant that made it possible!
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If you’d like to know more about the work I presented, carried out in collaboration with the Nitschke group at @ChemCambridge and the @MarchesanLab at @DSCF_UniTS, you can read our open-access paper here: doi.org/10.1002/anie.2024069….

Metal Ions Trigger the Gelation of Cysteine‐Containing Peptide‐Appended Coordination Cages

Three FeII4L4 metal-organic cages were fabricated via a L−D−L-tripeptide ligand with different sequences. The cages could form gels triggered by coordinating thiol groups of peripheral peptides...

onlinelibrary.wiley.com
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What a wonderful opportunity to be part of #EFMCISMC24 in Rome and to present my poster on AI and ML-based approaches for the design of new adenosine A2A antagonists in collaboration with @Evotec @MedChemLabUnits. Hope to see you at P467 stand! @EuroMedChem @UniTrieste
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I’m honoured to receive the prestigious Carlo Pedone Award 2024 for my PhD thesis. I would like to thank @itpeptsoc, its president Prof. Mangoni, the previous one Prof. Morelli and @EurPepSoc for the opportunity to present my thesis at 37th EPS and 14th IPS. #peptide #gel
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Last but not least, I would like to thank my supervisor Silvia Marchesan @MarchesanLab for her guidance and inspiration during these years.
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I am very honoured to have the opportunity to present at @SocChimIta National Congress this recently published paper doi.org/10.1002/anie.2024069… on @angew_chem, born from a collaboration between @MarchesanLab of @UniTrieste and #Nitschkegroup of @ChemCambridge.
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Honoured to write this piece for @Nature on the break-through by #GazitLab on #Selfhealing #glass from a simple #peptide — just add water nature.com/articles/d41586-0… @UniTrieste #materials #science #selfassembly

Self-healing glass from a simple peptide — just add water

Nature - A biomaterial with similar optical properties to conventional glass.

nature.com
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Happy to share the article relative to my master #thesis on #insulin fibrillation #inhibition. Thank you to my supervisor @MarchesanLab and @annagarfer for driving this work and to my cosupervisor @simoado for backing me up throughout the thesis. pubs.rsc.org/en/content/arti…

Insulin amyloid fibril formation reduction by tripeptide stereoisomers†

Insulin fibrillation is a problem for diabetic patients that can occur during storage and transport, as well as at the subcutaneous injection site, with lo

pubs.rsc.org
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A productive day at @elettrasincro to set the new Cryo stage for UV Resonance Raman spectroscopy with #BarbaraRossi #IUVS2.0
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Congrats to @annagarfer and @BeatriceRosetti for this interesting article on @nanoscale_rsc about inhibition of #insulin fibrillation. pubs.rsc.org/en/content/arti…

Insulin amyloid fibril formation reduction by tripeptide stereoisomers†

Insulin fibrillation is a problem for diabetic patients that can occur during storage and transport, as well as at the subcutaneous injection site, with lo

pubs.rsc.org
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And... Here it is!! Take a look to our contribution to the special issue in honor to il Prof. We're able to pattern graphene covalently using emulsions
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🥳 Congrats to @simoado 4 successfully defending hid #PhD in #Chemistry @DSCF_UniTS @UniTrieste @ the interface between #supramolecular chemistry & #nanomaterials!!! Well done!!! #gels #peptides #cages #selfassembly #composites #nanotechnology #materials #CNTs #nanotubes #carbon
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Finally Dr. in #chemistry. Thank you very much to my supervisor @MarchesanLab for her great support during all this #PhD 🧑‍🔬🎓#chemistry #supramolecularchemistry #peptide #MOCs #CNTs
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