Principal Product Manager @Dynatrace ex @Runecast CEO

Czech Republic
Joined May 2008
Stanimir Markov retweeted
With AlphaFold we mapped the protein universe - now with AlphaGenome Atlas we’re charting the human genome. It can predict the impact of all 9 billion possible single-letter DNA variants, helping scientists better understand disease. Freely available for academic research: alphagenome.google/atlas
We’re launching AlphaGenome Atlas: an AI-powered searchable database mapping the predicted impact of all 9 billion possible single-letter DNA changes. Here’s how it could help researchers better understand our biology 🧵
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Stanimir Markov retweeted
My cancer case is n=1. I'm not holding it up as a model, because most of what I did is not specifically replicable or scaleable. But it is a proof of concept that fully personalized medicine, built around one patient's own biology, is viable in ways it simply wasn't a few years ago. I have lived a version of the future of cancer care that I think is worth aspiring to more broadly. Many of the tools that made this future possible for me are getting better, faster, cheaper, and more accessible every year. I think what we need next is the infrastructure to deploy these tools, and the community willing to build this infrastructure, one patient at a time. I want to help that future arrive faster. I wrote an article in The Cancer Letter cancerletter.com/guest-edito… for the physicians and researchers closest to the patients who could benefit most from this approach, who also believe in this future. If you are working towards building the systems and practices that will make personalized medicine operationally real, we want to collaborate with you too.
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Stanimir Markov retweeted
Anyone who used a computer between 1985-2010. What’s the one game you still think about?
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Stanimir Markov retweeted
GitHub's former CEO gave his AI eyes. What happened next is equal parts hilarious and haunting
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Stanimir Markov retweeted
you can outsource your thinking but you cannot outsource your understanding
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I've never sen anything more accurate
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Stanimir Markov retweeted
VI. The Deepest Problem: Wants Are Infinite, Time Is Finite The most fundamental reason the lump-of-labor fallacy fails — in its AGI application as in all prior applications — is that human wants are effectively infinite and human time is absolutely finite. Even in a world where AGI can produce every good and service at near-zero cost, humans will still want things that are irreducibly scarce: other humans’ time and attention. A massage from another human. A meal cooked with love by a person who cares. A conversation with someone who genuinely listens. Live performance. Mentorship. Friendship. Community. Spiritual guidance. Teaching that is responsive to a specific child’s specific needs in real time. These things cannot be AGI-produced without losing the very quality that makes them valuable, because the value is constituted by the human origin. As AGI drives down the price of machine-produced goods and services, it increases the relative scarcity and therefore the relative value of genuine human connection and human time. The inevitable long-run consequence of AGI is not mass unemployment. It’s a massive repricing of human time upward, with employment shifting toward the domains where human presence is the product — and the expansion of service, care, craft, performance, and connection sectors to a scale that would dwarf current employment in those areas. Conclusion The AGI unemployment catastrophism is the Luddite fallacy wearing a PhD. It makes the same structural error every previous generation of technological catastrophists made — treating the quantity of work as fixed, ignoring the demand-creation and productivity-feedback mechanisms, conflating transitional friction with structural permanence, and ignoring comparative advantage and complementarity effects. The lump of labor fallacy is not a fringe economic insight. It is one of the most robustly empirically validated and theoretically grounded propositions in all of economics. The economy is not a fixed pie. Technology that increases productive capacity increases the size of the pie, and bigger pies employ more people doing more differentiated and higher-value work. AGI will disrupt. It will displace. It will create extraordinary transitional friction in specific occupations and geographies. It will reward people who adapt quickly and punish people who don’t. It will reshape the composition of employment radically. All of that is true and worth taking seriously. What it will not do — cannot do, given the basic logic of how market economies work — is produce permanent structural mass unemployment. The people making that argument are making a claim that has been empirically falsified ten times in a row over 250 years, grounded in a logical error that every serious economist since Bastiat has recognized as a fallacy. The burden of proof is entirely on them to explain what mechanism, precisely, breaks the demand-creation feedback loop that has operated without failure through every prior technological revolution in history. And “AGI is really really powerful this time” is not a mechanism. It’s just the Luddites in better clothes.
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Stanimir Markov retweeted
We are introducing EU Inc. To make building and growing a business across the EU faster, simpler, and smarter. 🔸 Start a company in less than 48 hours 🔸 No minimum capital requirement 🔸 Fully online and borderless
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Stanimir Markov retweeted
Agency > Intelligence I had this intuitively wrong for decades, I think due to a pervasive cultural veneration of intelligence, various entertainment/media, obsession with IQ etc. Agency is significantly more powerful and significantly more scarce. Are you hiring for agency? Are we educating for agency? Are you acting as if you had 10X agency? Grok explanation is ~close: “Agency, as a personality trait, refers to an individual's capacity to take initiative, make decisions, and exert control over their actions and environment. It’s about being proactive rather than reactive—someone with high agency doesn’t just let life happen to them; they shape it. Think of it as a blend of self-efficacy, determination, and a sense of ownership over one’s path. People with strong agency tend to set goals and pursue them with confidence, even in the face of obstacles. They’re the type to say, “I’ll figure it out,” and then actually do it. On the flip side, someone low in agency might feel more like a passenger in their own life, waiting for external forces—like luck, other people, or circumstances—to dictate what happens next. It’s not quite the same as assertiveness or ambition, though it can overlap. Agency is quieter, more internal—it’s the belief that you *can* act, paired with the will to follow through. Psychologists often tie it to concepts like locus of control: high-agency folks lean toward an internal locus, feeling they steer their fate, while low-agency folks might lean external, seeing life as something that happens *to* them.”
Intelligence is on tap now so agency is even more important
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Stanimir Markov retweeted
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Good morning Vegas! An exciting day at @Dynatrace Perform is about to start!
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My colleagues from #appsec have shared some more #security related dashboards. While its focused on #Dynatrace I think seeing the data we put on dashboards should help everyone More security related dashboards to be found on my GitHub: github.com/dynatrace-perfcli… – at Denver, CO
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Stanimir Markov retweeted
📢 We are happy to announce that we've won the following @TEISS Awards 2024! 🎉 🔒 Best Security #Compliance Product 🏆 🛡️ Best #VulnerabilityManagement Solution 🏆 Big congrats to all the winners and finalists shown here: hubs.li/Q02m1X2r0 #CSPM #CWPP #CNAPP
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Stanimir Markov retweeted
🔔 We’re looking forward to the next #RuneTalk #Meetup. See you tomorrow at 18:00 at Alterna Music Bar (Kounicova 506/48, Brno, Czech Republic). 🔔 Read more and secure your last-minute spot: hubs.ly/Q02jjsRd0
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Stanimir Markov retweeted
We're excited to share Runecast 6.9 🎉, which introduces even more enhancements for agentless scanning. Let’s dive in and explore what’s new! hubs.li/Q02l8scD0
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Stanimir Markov retweeted
Webinar 📢 Secure & Compliant Workloads Anywhere (deutsche) 🗓️ 15. Februar 2024, 11:00-12:00 CET 🎙️ Veranstaltet von der @PriantoGmbH, mit Vural Aybar, Runecast Sales Director 🛡️ #GRC/#Compliance für #DORA, #BSI, #TISAX und mehr 🔒 ➡️ Jetzt anmelden: hubs.li/Q02hnw0W0
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Stanimir Markov retweeted
Does your #ITsecurity team ignore #vulnerabilities with low CVSS score because of too many high-scoring ones to remediate? 🔥🙈 What if you could see low-scoring ones that are among #CISA's KEVs? 🔎⚙️ ➡️ Run your own #VulnerabilityAssessment today: hubs.li/Q02jlghl0
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Stanimir Markov retweeted
We are excited to announce the first session for our upcoming #RuneTalk meetup by Vasile Papp and Aylin Sali (@V4Virtual). They’ll delve into ethical cloning and non-invasive deep scanning, where they'll redefine system administration. Secure your spot: hubs.li/Q02jrQ6p0
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