Avantika Negi retweeted
We love seeing your creative interpretations 🦖
But our name is still Plasmidsaurus.
💚
Avantika Negi retweeted
Google Brain founder, Andrew Ng:
"Prompting will be dead in 6 months, graphs are what's replacing it."
In 2 hours at Stanford he shows how to build agents that work and improve entirely on their own.
The first 10 minutes cover what most $500 courses never do.
Watch the lecture first, then read the guide below on how to build a system that improves itself.
Avantika Negi retweeted
I am building an extremely sophisticated biomedical science application with GPT-6 Astra for analyzing flow cytometry data.
Flow cytometry is one of the most essential technologies in immunology. It allows us to analyze tens of thousands, or even millions, of individual cells from blood, tissues, or other samples, using fluorescently tagged antibodies that identify specific cell types and measure the proteins they express. It's like our window into the world of the cells.
For decades, labs like mine have paid thousands of dollars every year in subscription and licensing fees for commercial software to analyze these datasets. I have canceled all my subscriptions 😊
I have now almost built a fully functional, research-grade version of such an application with Astra! It already has a better UI/UX than many of the tools I have used, and my goal now is to make it even better than the leading commercial applications in this field!
I had in fact built earlier basic versions using previous Codex models, but this is the first time I have reached a version that works exactly the way I want it to, with the interface, analysis workflow, and features behaving almost perfectly. Previous versions took a lot of efforts with many bugs to deal with, with Astra you get what you ask for almost the first shot! It's just unbelievable!
And this is only one project. I have several other highly complex biological and biomedical software applications in my Astra pipeline. At this point, my main bottlenecks are basically token limits and the number of hours I can stay awake and massive coffee stocks! 😂
It is just incredible to think that scientific software that once required specialized development teams, years of engineering, and sometimes million dollar budgets can now be built by someone like me who has no software engineering experience!
With Astra you can just do things! ✨
Avantika Negi retweeted
Chi, Saeki, @yokomizo_t et al. demonstrate that 12-HHT-BLT2 signaling protects alveolar epithelial cells from pore-forming toxin-induced damage by promoting membrane repair, suggesting a new therapeutic strategy for bacterial infections. hubs.la/Q04wz4Nh0
#Biochemistry
Avantika Negi retweeted
Spatial-ATAC-Hi-C enables profiling chromatin accessibility and spatial organization, as shown in mouse and human brain samples.
nature.com/articles/s41592-0…
Claude Fable 5.1 is available everywhere today. Claude Mythos 5.1, our model for cyberdefenders and life scientists, is available through trusted access programs.
Read more: anthropic.com/claude-fable-a…
Avantika Negi retweeted
New analysis panel in NimbusImage let's you do flow cytometry-style gating on your objects!
Avantika Negi retweeted
Our September issue is now live!
nature.com/neuro/volumes/29/…
Avantika Negi retweeted
Raman Enhanced Delineation of Cell Atlases in Tissues (REDCAT) integrates stimulated Raman scattering microscopy and high-plex immunofluorescence to profile proteins, lipids, nuclear metabolites and redox metabolism in tissue.
nature.com/articles/s41592-0…
Avantika Negi retweeted
LLMs are allowing researchers to build software tools without support from software engineers.
nature.com/articles/s41592-0…
Avantika Negi retweeted
Our new paper in @NatureChemistry expands what chemistry living cells can perform, using engineered enzymes for unnatural biosynthesis to generate and transfer nitrenes, producing previously inaccessible nitrogenous compounds. Check it out: nature.com/articles/s41557-0…
Avantika Negi retweeted
A Perspective from Deininger, Caldarelli, Zernicka-Goetz, and Mikut examines the role of AI-based image analysis as applied to stem cell-derived models.
nature.com/articles/s41592-0…
Avantika Negi retweeted
De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics
nature.com/articles/s41467-0…
Avantika Negi retweeted
Fat storage in the body relies on specialized structures called lipid droplets. In a new Science study, researchers identified the microprotein adipogenin as a regulator of adipocyte lipid droplet size, revealing a key mechanism in lipid homeostasis.
Learn more in this week's issue: scim.ag/47FPKoj

ALT Lipid droplet growth is orchestrated by the seipin complex, which provides a structural platform for droplet nucleation and expansion. The microprotein adipogenin fine-tunes seipin’s conformation, remodeling its architecture to regulate lipid storage capacity. This modulation results in the formation of fewer but larger lipid droplets, revealing a key mechanism in lipid homeostasis.
Avantika Negi retweeted
Excited to share a new preprint from our lab: We identify calcium influx at ER-plasma membrane contact sites as a key mechanism regulating brown adipocyte thermogenesis and metabolic health.
biorxiv.org/content/10.64898…
Avantika Negi retweeted
This makes good sense 👇
Indeed, I recommend that students write a review paper that serves as Thesis Introduction and that their papers/preprints are pasted as Thesis Chapters in the required format.
Replying to @JSheltzer
Instead, I’d suggest a two-paper requirement: one must be research and the second could be a review, a methods paper, or an additional research article. Submitted, not necessarily accepted, preprints are fine, and the option to petition for an exemption on a case-by-case basis.
Avantika Negi retweeted
We, the Weizmann Institute of Science community, deeply mourn the passing of Prof. Ada Yonath of the Institute’s Chemical and Structural Biology Department. Prof. Yonath pioneered the study of the ribosome, the cell’s protein factory, and was awarded the 2009 Nobel Prize in Chemistry for her research in this field. Her decades-long scientific journey led to an understanding of how various antibiotics work, helping pave the way for the development of new antibiotics and the fight against antibiotic-resistant bacteria.
Yonath, the first Israeli woman scientist to win a Nobel Prize, also received dozens of other awards and honors, including the Israel Prize in Chemistry and the Wolf Prize in Chemistry. Prof. Yonath exemplified how scientific vision, the courage to choose a major scientific question and unwavering dedication to its pursuit can lead to extraordinary achievements and expand the boundaries of knowledge for the future of humanity.
May her memory be a blessing.
bit.ly/ada-yonath-eng
Avantika Negi retweeted
DNA in the nuclei of cancer cells videoed through a spinning disk confocal microscope. The first cell going through cell division got the assignment: one nucleus becomes two nuclei. The second cell, not so much. #CellBiology
Avantika Negi retweeted
Intact Actin: Tag called IntAct-U-ExM enables super-resolution of actin networks by expansion microscopy
📸 @anubhav_dhar et al @syncellbiolab @iiscbangalore in @PLOSBiology
➡️ bpod.org.uk/archive/2026/8/2… with @AntDLewis





























