@sciencethecat

senior scientist @HHMIJanelia. single particle tracking & #microscopy. @harvardccb PhD on enzymatic dynamics. https://xitter.cf/t.co/mvQvicc064

 Arlington, VA
scholar.google.com/citations?user=UzGfR3MAAAAJ&hl=en
Joined November 2008
  • Tweets2.1K
  • Following2.9K
  • Followers2.7K
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Brian English🔬 retweeted
Daniel Feliciano@DanielF46660275Sep 26
Multi-organelle signatures map cell-state diversity and metabolic adaptation in tissues | Science science.org/doi/10.1126/scie…

Multi-organelle signatures map cell-state diversity and metabolic adaptation in tissues

Cell-state diversity drives tissue adaptability, repair, and disease resilience, but capturing this complexity is a challenge. Current approaches rely on transcriptional profiling and overlook...

science.org
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Brian English🔬 retweeted
Andy Moore@aaandmooreSep 17
Thank you to the folks @NikonSmallWorld and this year's panel of judges for selecting my videos for the 2026 Nikon Small World in Motion competition! Have a look at all the winning videos at the link below.
Nikon Small World@NikonSmallWorldSep 16
Presenting... 🥁 ... The 2026 Nikon Small World in Motion winners! Congratulations to all of our winners, and thank you again to everyone who entered! The full gallery is available to view now: nikonsmallworld.com/gallerie…!
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Heloisa and I just got the next-gen Covid shot at Costco. mNEXSPIKE is a lower-dose (10 vs 50 mcg mRNA), more targeted option than Spikevax. It may also produce a stronger immune response, so get this one! @Heloisarts #covid #moderna @Costco
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Brian English🔬 retweeted
Bill Katz@wtkatzSep 3
Our male CNS paper is out in Cell.
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with @Heloisarts from our balcony, lots of clouds but we got a little lucky – at Arlington, VA
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What would it feel like to go with the flow inside a cell? A lovely new Current Biology Dispatch by Dyche Mullins on work led by Cathy & Jim Galbraith "expands our cellular imagination" to the cell's own sluices, pumps & dams. doi.org/10.1016/j.cub.2026.0… doi.org/10.1038/s41467-026-7…
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So grateful to @MullinsLab for the kind write-up — and truly lucky to have chased this from so many technical angles with @GalbraithLab & @Ulrike_Boehm.
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Brian English🔬 retweeted
C&J Galbraith@GalbraithLabJul 10
We were asked by @focalplane_jcs for the behind the paper story on our recent work uncovering Compartmentalized Cytoplasmic Tradewinds. Read about it here. (along with a new YouTube video). A great collaboration with @sciencethecat and @Ulrike_Boehm focalplane.biologists.com/20…

Cytoplasmic Tradewinds: How Cells Steer Proteins

Six imaging methods reveal cytoplasmic tradewinds: a hidden fluid flow that pushes soluble proteins using a leaky actin-myosin barrier.

focalplane.biologists.com
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Brian English🔬 retweeted
Derek Rae@RaeCommJun 16
We are so lucky to see Olise perform these feats of magic in the Bundesliga every week.
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All the countries I've lived in: 🇩🇪 (7:1 win) 🇸🇪 (5:1 win) 🇺🇸 (4:1 win) 🍀⚽🍀⚽🍀⚽ I'm clearly a lucky charm and I'm ready to accept immigration proposals.
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Brian English🔬 retweeted
Nature Methods@naturemethodsJun 12
Our June issue is live! 🎉 nature.com/nmeth/volumes/23/… On the cover, an absolutely gorgeous image of neurites and mitochondria in a brain organoid, captured using the MOSAIC microscope. Paper here: nature.com/articles/s41592-0…
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Brian English🔬 retweeted
SunneyXie@XieSunney14 May 2025
Congrats to Rita, Ji-Xin, Wei and Meng for the special issue of Nature Methods on vibrational imaging (nature.com/nmeth/volumes/22/…). Happy to share my account for the 25 years of Nonlinear Raman imaging. Thanks to all former group members and collaborators for their contributions.
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Happy Pride Month ❤️🤍🏳️‍🌈
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Brian English🔬 retweeted
Eric Betzig
@Eric_BetzigMay 22
Congrats to all 49 authors on the publication of our paper on the multimodal MOSAIC microscope, to be found here: nature.com/articles/s41592-0… A summary with movies I posted nearly a year ago can be found below.

A multimodal adaptive optical microscope for in vivo imaging from molecules to organisms

Nature Methods - MOSAIC is a versatile multimodal microscope that allows seamless transition between various light-sheet, two-photon, label-free and super-resolution modalities. It is demonstrated...

nature.com
Eric Betzig
@Eric_Betzig21 Jul 2025
1/ Better late than never, here’s a long thread of threads summarizing our MOSAIC preprint. If you’re curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If you’ve come for eye candy, there’s plenty of that too below. biorxiv.org/content/10.1101/…

A Multimodal Adaptive Optical Microscope For In Vivo Imaging from Molecules to Organisms

Understanding biological systems requires observing features and processes across vast spatial and temporal scales, spanning nanometers to centimeters and milliseconds to days, often using multiple...

biorxiv.org
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Brian English🔬 retweeted
Kevin Elliott@PunkgiMay 4
Replying to @deniswirtz @Stanford @Penn @Harvard @Cambridge_Uni @ETH_en @UMich @UCLA @UCSFimaging @MIT @salkinstitute
Heres the paper for those who don't want to wait: biorxiv.org/content/10.64898…

Whole organism 3D mapping reveals universal branching topology and biophysical optimization governs...

The vascular and nervous systems are transport networks essential for life, yet whether universal geometric and topological principles govern their formation remains unclear. The organism-wide...

biorxiv.org
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Brian English🔬 retweeted
C&J Galbraith@GalbraithLabApr 19
It all started with: (#2 in the series) New in @naturemethods: spontaneously blinking dyes for live cell super-res. No harsh cocktails or light. Watch Cathy and @sciencethecat apply the dyes. nature.com/articles/s41592-0… 2nd Nature family paper in two weeks🤯 nature.com/articles/s41467-0…
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Blinking dyes from the Lavis lab @HHMIJanelia @GalbraithLab @jonathangrimm @ohsunews #SOFI #PALM #OpenScience via @EurekAlert: eurekalert.org/news-releases…

New imaging tools help cancer researchers see inside living cells

A new study co-led by an Oregon Health & Science University researcher describes a breakthrough in microscopy tools that could dramatically expand how cancer biology labs study the inner workings of...

eurekalert.org
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Brian English🔬 retweeted
C&J Galbraith@GalbraithLabApr 3
Video explainer by @GalbraithLab with @sciencethecat @Ulrike_Boehm @HHMIJanelia @AICjanelia @MBLScience @OHSUNews @OHSUKnight
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What if cells have undiscovered methods for managing their internal logistics? Our recent work (@GalbraithLab, @sciencethecat & myself) challenges existing views on intracellular transportation 🔗 lnkd.in/dhMDgY5Q
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So excited to share this work that employs #FCS, TIRF, FRAP, SPT, SIM & #iPALM. Huge thanks to Cathy and Jim (@GalbraithLab), and @Ulrike_Boehm (the iPALM wizard) #OpenScience @HHMIJanelia #CellBiology #Cytoskeleton #SuperResolution #Microscopy @hhmi_science
OHSU Knight Cancer Institute@OHSUKnightMar 30
Scientists at @OHSUNews have uncovered an unknown system of internal “trade winds” that help cells move essential proteins to the front of the cell, reshaping how researchers understand cell migration, cancer spread and wound healing. #OHSUResearch: news.ohsu.edu/2026/03/30/ohs…

OHSU study uncovers internal cell ‘trade winds’ that drive movement and repair

Breakthrough research reveals that cells use directed fluid flows to push key proteins forward, offering new insights into cancer, immunity, wound healing.

news.ohsu.edu
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