@sciRPatel

Computational Immunologist | Data Scientist @UCSF | PhD '20 @Cornell | Father & Husband #Bioinformatics #Multiomics #SingleCell #Immunology #SystemsImmunology

profiles.ucsf.edu/ravi.patel
Joined July 2020
  • Tweets62
  • Following228
  • Followers133
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Ravi K. Patel retweeted
Aartik Sarma@AartikSarma28 Jun 2024
Steroids have *compartment-specific* effects in patients with COVID-19 ARDS! Results highlight importance of studying injured organs directly when possible @NatureComms with Lucile Neyton, @sciRPatel, @GabiFragiadakis and colleagues nature.com/articles/s41467-0…

Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19

Nature Communications - Dexamethasone has been used in the treatment of critically ill COVID-19 patients. Here the authors apply transcriptomics to investigate the effects of dexamethasone...

nature.com
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📢Greetings! We are accepting submissions for 'Systemic immune response through a multi-omic lens' @FrontImmunol Please share this with anyone working on #systemsImmunology #immunology #multiomics #integrativeAnalysis #infectiousdisease #autoimmunity frontiersin.org/research-top…

Frontiers | Unraveling Systemic Immune Responses Through Multi-Omics Integration

The field of immunology has long been focused on understanding the complex mechanisms by which the immune system defends the host against pathogens. However,...

frontiersin.org
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I am excited to share that our #IMPACC paper - Integrated longitudinal multi-omics study identifies immune programs associated with acute COVID-19 severity and mortality - was recently published in @jclinicalinvest. jci.org/articles/view/176640 #SystemsBiology #Bioinformatics [1/5]
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Ravi K. Patel retweeted
KattahLab@MikeKattahMD12 Mar 2024
Excited to share our manuscript on single-cell and spatial multi-omics of anti-integrin therapy in ulcerative colitis (UC) nature.com/articles/s41467-0…. This work was led by @ElviraMennillo, in collaboration with @alexis_combes, @GabiFragiadaks, and @drAOPisco 1/8
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Not at all jumping on the AI rodent band wagon, but delighted to announce the publication of our paper in @MucosalImmunol about why you lose your appetite when you have a cold pubmed.ncbi.nlm.nih.gov/3838… Including the coolest experiment I have ever done
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New research in mice finds that neonatal CD8+ T cells can undergo rapid chromatin remodeling, which supports their innate-like functions. Read more: scim.ag/607 @Cornell @CornellCFI
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Replying to @SciImmunology
This paper is beautiful ➡️ science.org/doi/10.1126/scii… To be paired with this vintage 💎 science.org/doi/10.1126/scie…
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A new @SciImmunology study describes why a subset of T cells behaves in a way that is more similar to innate immune cells, rather than responding like normal adaptive immune cells. Learn more: scim.ag/603
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How do neonates with primitive immune system survive in the world? We found: (1/5) @SciImmunology (in Rudd & Grimson labs; with Neva & Connor, fellow Tweeters @Oyeb2003 @CybelleTabilas @kristel_yee @eliataitwojno) #SingleCell #multiomics #neonatalImmunity scim.ag/5Z2

The gene regulatory basis of bystander activation in CD8+ T cells

A multi-omic analysis reveals distinct programs of bystander activation in CD8+ T cells produced at various stages of life.

science.org
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3) Neonatal CD8+ T-cells provide protection against bacterial, viral and parasitic pathogens. (4/5)
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4) 'Keep the child within us alive'. Highly reactive, innate-like T cells of childhood are also found in adulthood in both mice and humans, changing how we think about the T-cell biology in adults. (5/5)
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'Keep the child within us alive'. Highly reactive, innate-like T cells of childhood are also found in adulthood in both mice and humans, changing how we think about the T-cell biology in adults scim.ag/5Z2 @SciImmunology #SingleCell #multiomics #neonatalImmunity

The gene regulatory basis of bystander activation in CD8+ T cells

A multi-omic analysis reveals distinct programs of bystander activation in CD8+ T cells produced at various stages of life.

science.org
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How do neonates survive with primitive adaptive immune system? Read about the functionally diverse pool of CD8+ T-cells that may compensate for the primitive adaptive immune system of neonates. scim.ag/5Z2 @SciImmunology #SingleCell #multiomics #neonatalImmunity

The gene regulatory basis of bystander activation in CD8+ T cells

A multi-omic analysis reveals distinct programs of bystander activation in CD8+ T cells produced at various stages of life.

science.org
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Read about another fantastic collaboration of Rudd-Grimson lab on innate-like CD8+ T-cells in mice and humans.
Science Immunology@SciImmunology23 Feb 2024
A new study in mice describes the activation programs of neonatal innate-like CD8+ #TCells, spotlighting the roles of #TranscriptionFactors Bach2 and AP-1. Learn more: scim.ag/5Z2 @Cornell @CornellCFI
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The newest story from the Rudd lab is out! Read about how CD8+ T cells are more than just their T cell receptor! Congrats to @sciRPatel et al science.org/doi/10.1126/scii…

The gene regulatory basis of bystander activation in CD8+ T cells

A multi-omic analysis reveals distinct programs of bystander activation in CD8+ T cells produced at various stages of life.

science.org
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A new study in mice describes the activation programs of neonatal innate-like CD8+ #TCells, spotlighting the roles of #TranscriptionFactors Bach2 and AP-1. Learn more: scim.ag/5Z2 @Cornell @CornellCFI
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Excited to share a call for submission to a topic 'Systemic immune response through a multi-omic lens' @FrontImmunol. Please share this with anyone working on #systemsImmunology #immunology #multiomics #integrativeAnalysis #infectiousdisease #autoimmunity frontiersin.org/research-top…

Frontiers | Unraveling Systemic Immune Responses Through Multi-Omics Integration

The field of immunology has long been focused on understanding the complex mechanisms by which the immune system defends the host against pathogens. However,...

frontiersin.org
Pieter Meysman@chevaliersf24 Jan 2024
Delighted to join forces with @sciRPatel, @ElviraMennillo, and @JoannDArce as a Topic Editor for a #systems #immunology issue at @FrontImmunol. The first hurdle: finding contributors to showcase groundbreaking research in the field of #multiomics ! frontiersin.org/research-top…

Frontiers | Unraveling Systemic Immune Responses Through Multi-Omics Integration

The field of immunology has long been focused on understanding the complex mechanisms by which the immune system defends the host against pathogens. However,...

frontiersin.org
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Excited to present a team of fantastic co-editors @ElviraMennillo, @JoannDArce, & @Chevaliersf.
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