Pontecorvo Chair of Pharmacogenomics Professor of Cardiovascular Genomics and Therapeutics Hypertension, Precision Medicine, Digital Health

Glasgow, Scotland
Joined April 2009
Our Pharmacogenomics Lead, and Pontecorvo Chair of Pharmacogenomics, Professor @sandp27, attended the Global Genomics Conference. He shared his insight on driving the health economic case for #genomics implementation in health systems, using the PHOENIX trial as a key exemplar.
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Sandosh Padmanabhan retweeted
The panel will be chaired by @John_H_McD, and the other panellists are Sandosh Padmanabhan (@sandp27) and Samantha Roberts (@SamRobertsNHS). For more details, registration and the full agenda: live.publicpolicyprojects.co… [2/2]
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From GWAS to novel mechanism and clinical trial - hypertension precision medicine. New research funded by the British Heart Foundation, and published in the journal Hypertension. Here are the details in 10 tweets. #umod #hypertension #gwas #torasemide ahajournals.org/doi/full/10.…
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We were delighted to have Professor @sandp27 speak at the @GenomicsEngland Research Summit this month. His talk, ‘On the road to #Pharmacogenomics Implementation in Scotland’, highlighted our PHOENIX project and its ambitions for a world-leading clinical trial in Glasgow.
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Sandosh Padmanabhan retweeted
💭 Machine learning may have potential for blood pressure classification and risk stratification in hypertensive patients in the absence of ambulatory blood pressure monitoring, but cannot replace it. Read more 👉 cjcopen.ca/article/S2589-790… @sandp27 #ML #ABPM #CJCO #OpenAccess
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Sandosh Padmanabhan retweeted
Hypertension is a risk factor in the development of CKD. This study suggests sodium bicarbonate supplementation does not adversely affect systolic BP or negatively influence antihypertensive medication requirements bit.ly/CJASN0119 @theCKDdietitian @sandp27 @GlasgowBP
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4/ The study highlights ML's potential but also its limitations. Larger, diverse studies are needed to improve accuracy and validate these findings. ABPM remains the gold standard for now, but ML could be a useful tool where ABPM isn't available.
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5/ Implementing ML in hypertension management could revolutionise treatment, especially in resource-poor settings. However, ethical deployment requires involving patients, healthcare providers, and stakeholders from the start. The journey is promising but requires careful steps.
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6/ More research is essential to refine ML models and ensure they can complement or even replace ABPM in the future. The potential to enhance hypertension management across diverse healthcare environments is immense.
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Sandosh Padmanabhan retweeted
CENTENNIAL PERSPECTIVE: Beyond Genome-Wide Scans: Advancing Hypertension Genomics Into the Future ahajrnls.org/3VfqVuu
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Mapping hypertension treatment and genomics. See how the nearly independent parallel paths of drug development, monogenic syndromes, and GWAS are converging to transform patient care. @HyperAHA ahajrnls.org/3VfqVuu #Centennial @munroe_patsy @UofGRegiusAnna @UofGSCMH
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Sandosh Padmanabhan retweeted
Our wonderful group of volunteers this morning to measure blood pressure for World Hypertension Day @UofGSCMH @MayMeasureOrg @BHFScotland @BHFCoREGlasgow @GlasgowBP We are here today from 9 - 12 and 1-4
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Sandosh Padmanabhan retweeted
❤️ الحمد لله Happy to announce that our new paper on Artificial Intelligence and Polypharmacy has just been published in @HealthcareMDPI_ Grateful to work with @sandp27 #Umm_AlQura_University #Glagow_University #Saudi_Vision_2030_Healthcare_Programs
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Sandosh Padmanabhan retweeted
@sandp27 discusses the #CPPrecisionmedicine article: Cardiovascular precision medicine – A pharmacogenomic perspective. Read the full article here: bit.ly/43HFrfz @UofGRegiusAnna #precisionmedicine #pharmacogenomics #genomics #pharmaceutical
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A warm welcome to @NgocLe2111, the new postdoctoral research assistant to the Pontecorvo Chair @UofGSCMH. With her outstanding expertise in mendelian randomisation and genomic analysis, she's set to make significant strides in pharmacogenomic research.
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Huge congratulations to Dr. Stefanie Lip for receiving the prestigious John Munro Medal from the Royal College of Physicians Edinburgh! An honor for her exceptional work as Deputy Lead Clin. Pharm @UofG, Medicines Safety Month and her innovative app for trainees and QIP.
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